5C4J
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![BU of 5c4j by Molmil](/molmil-images/mine/5c4j) | Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G. | 登録日 | 2015-06-18 | 公開日 | 2015-08-26 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble. Mol.Cell, 59, 2015
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7Q5B
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![BU of 7q5b by Molmil](/molmil-images/mine/7q5b) | Cryo-EM structure of Ty3 retrotransposon targeting a TFIIIB-bound tRNA gene | 分子名称: | DNA (19-MER), DNA (31-MER), DNA (34-MER), ... | 著者 | Abascal-Palacios, G, Jochem, L, Pla-Prats, C, Beuron, F, Vannini, A. | 登録日 | 2021-11-03 | 公開日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes. Nat Commun, 12, 2021
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1EF4
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![BU of 1ef4 by Molmil](/molmil-images/mine/1ef4) | SOLUTION STRUCTURE OF THE ESSENTIAL RNA POLYMERASE SUBUNIT RPB10 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM | 分子名称: | DNA-DIRECTED RNA POLYMERASE, ZINC ION | 著者 | Mackereth, C.D, Arrowsmith, C.H, Edwards, A.M, Mcintosh, L.P, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2000-02-07 | 公開日 | 2000-06-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum. Proc.Natl.Acad.Sci.USA, 97, 2000
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8RBX
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![BU of 8rbx by Molmil](/molmil-images/mine/8rbx) | Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | 登録日 | 2023-12-05 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
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8A43
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![BU of 8a43 by Molmil](/molmil-images/mine/8a43) | Human RNA polymerase I | 分子名称: | DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ... | 著者 | Daiss, J.L, Pilsl, M, Straub, K, Bleckmann, A, Hoecherl, M, Heiss, F.B, Abascal-Palacios, G, Ramsay, E, Tluckova, K, Mars, J.C, Fuertges, T, Bruckmann, A, Rudack, T, Bernecky, C, Lamour, V, Panov, K, Vannini, A, Moss, T, Engel, C. | 登録日 | 2022-06-10 | 公開日 | 2022-08-31 | 最終更新日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | 主引用文献 | The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans. Life Sci Alliance, 5, 2022
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7NVR
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![BU of 7nvr by Molmil](/molmil-images/mine/7nvr) | Human Mediator with RNA Polymerase II Pre-initiation complex | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Rengachari, S, Schilbach, S, Aibara, S, Cramer, P. | 登録日 | 2021-03-15 | 公開日 | 2021-05-05 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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4BBS
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![BU of 4bbs by Molmil](/molmil-images/mine/4bbs) | Structure of an initially transcribing RNA polymerase II-TFIIB complex | 分子名称: | 5'-D(*AP*GP*CP*GP*CP*AP*GP*TP*TP*GP*TP*GP*CP*TP *AP*TP*GP*AP*TP*AP*TP*TP*TP*TP*TP*AP*TP)-3', 5'-D(*GP*GP*CP*AP*CP*AP*AP*CP*TP*GP*CP*GP*CP*TP)-3', 5'-R(*AP*UP*AP*UP*CP*AP)-3', ... | 著者 | Sainsbury, S, Niesser, J, Cramer, P. | 登録日 | 2012-09-27 | 公開日 | 2012-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure and Function of the Initially Transcribing RNA Polymerase II-TFIIB Complex Nature, 493, 2013
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4BBR
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![BU of 4bbr by Molmil](/molmil-images/mine/4bbr) | Structure of RNA polymerase II-TFIIB complex | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | 著者 | Sainsbury, S, Niesser, J, Cramer, P. | 登録日 | 2012-09-27 | 公開日 | 2012-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure and Function of the Initially Transcribing RNA Polymerase II-TFIIB Complex Nature, 493, 2013
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6TPS
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![BU of 6tps by Molmil](/molmil-images/mine/6tps) | |
4BY7
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![BU of 4by7 by Molmil](/molmil-images/mine/4by7) | elongating RNA Polymerase II-Bye1 TLD complex | 分子名称: | , 5'-D(*DAP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*DTP)-3', 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. | 登録日 | 2013-07-18 | 公開日 | 2013-09-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
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4BY1
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![BU of 4by1 by Molmil](/molmil-images/mine/4by1) | elongating RNA Polymerase II-Bye1 TLD complex soaked with AMPCPP | 分子名称: | 5'-D(*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP *TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*AP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ... | 著者 | Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. | 登録日 | 2013-07-17 | 公開日 | 2013-09-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
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4BXX
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![BU of 4bxx by Molmil](/molmil-images/mine/4bxx) | Arrested RNA polymerase II-Bye1 complex | 分子名称: | 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*AP*CP*CP*TP*GP *GP*TP*GP* BRUP*TP*GP*CP*TP*CP*TP*AP*AP*DC)-3', 5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP)-3', 5'-D(*GP*AP*GP*GP*TP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', ... | 著者 | Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. | 登録日 | 2013-07-16 | 公開日 | 2013-09-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.28 Å) | 主引用文献 | Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
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2B8K
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![BU of 2b8k by Molmil](/molmil-images/mine/2b8k) | 12-subunit RNA Polymerase II | 分子名称: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... | 著者 | Meyer, P.A, Ye, P, Zhang, M, Suh, M.H, Fu, J. | 登録日 | 2005-10-07 | 公開日 | 2006-06-20 | 最終更新日 | 2012-06-13 | 実験手法 | X-RAY DIFFRACTION (4.15 Å) | 主引用文献 | Phasing RNA Polymerase II Using Intrinsically Bound Zn Atoms: An Updated Structural Model. Structure, 14, 2006
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1WCM
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![BU of 1wcm by Molmil](/molmil-images/mine/1wcm) | Complete 12-Subunit RNA Polymerase II at 3.8 Angstrom | 分子名称: | DNA-DIRECTED RNA POLYMERASE II 13.6 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KD POLYPEPTIDE, ... | 著者 | Armache, K.-J, Mitterweger, S, Meinhart, A, Cramer, P. | 登録日 | 2004-11-17 | 公開日 | 2004-12-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structures of Complete RNA Polymerase II and its Subcomplex,Rpb4/7 J.Biol.Chem., 280, 2005
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1NIK
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![BU of 1nik by Molmil](/molmil-images/mine/1nik) | Wild Type RNA Polymerase II | 分子名称: | DNA-directed RNA polymerase I, II and III 23 kDa polypeptide, DNA-directed RNA polymerase II, ... | 著者 | Bushnell, D.A, Kornberg, R.D. | 登録日 | 2002-12-24 | 公開日 | 2003-04-29 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Complete, 12-subunit RNA Polymerase II at 4.1-A resolution: implications for the initiation of transcription. Proc.Natl.Acad.Sci.USA, 100, 2003
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1Y77
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![BU of 1y77 by Molmil](/molmil-images/mine/1y77) | Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP | 分子名称: | 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*T*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*G)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ... | 著者 | Kettenberger, H, Armache, K.-J, Cramer, P. | 登録日 | 2004-12-08 | 公開日 | 2005-01-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS Mol.Cell, 16, 2004
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1Y1W
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![BU of 1y1w by Molmil](/molmil-images/mine/1y1w) | Complete RNA Polymerase II elongation complex | 分子名称: | 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*AP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ... | 著者 | Cramer, P, Kettenberger, H, Armache, K.-J. | 登録日 | 2004-11-19 | 公開日 | 2005-01-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS Mol.Cell, 16, 2004
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1Y1V
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![BU of 1y1v by Molmil](/molmil-images/mine/1y1v) | Refined RNA Polymerase II-TFIIS complex | 分子名称: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... | 著者 | Kettenberger, H, Armache, K.-J, Cramer, P. | 登録日 | 2004-11-19 | 公開日 | 2004-12-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS. Mol.Cell, 16, 2004
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8HIL
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![BU of 8hil by Molmil](/molmil-images/mine/8hil) | A cryo-EM structure of B. oleracea RNA polymerase V at 3.57 Angstrom | 分子名称: | DNA-dependent RNA polymerase IV and V subunit 2, DNA-directed RNA polymerase V largest subunit, DNA-directed RNA polymerase subunit, ... | 著者 | Du, X, Xie, G, Hu, H, Du, J. | 登録日 | 2022-11-20 | 公開日 | 2023-03-22 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | Structure and mechanism of the plant RNA polymerase V. Science, 379, 2023
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8HIM
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![BU of 8him by Molmil](/molmil-images/mine/8him) | A cryo-EM structure of B. oleracea RNA polymerase V elongation complex at 2.73 Angstrom | 分子名称: | DNA (34-MER), DNA-directed RNA polymerase IV and V subunit 2, DNA-directed RNA polymerase V largest subunit, ... | 著者 | Hu, H, Xie, G, Du, X, Du, J. | 登録日 | 2022-11-21 | 公開日 | 2023-03-22 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure and mechanism of the plant RNA polymerase V. Science, 379, 2023
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3HOW
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![BU of 3how by Molmil](/molmil-images/mine/3how) | Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine | 分子名称: | 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... | 著者 | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | 登録日 | 2009-06-03 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
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3HOY
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![BU of 3hoy by Molmil](/molmil-images/mine/3hoy) | Complete RNA polymerase II elongation complex VI | 分子名称: | 5'-D(*CP*CP*AP*AP*GP*CP*TP*CP*AP*AP*G*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*TP*AP*CP*TP*AP*GP*TP*AP*CP*TP*GP*CP*C)-3', 5'-D(*CP*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*AP*GP*TP*AP*AP*AP*CP*TP*AP*GP*TP*AP*TP*T*GP*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP*T)-3', 5'-R(*UP*AP*UP*AP*UP*GP*CP*A*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*A)-3', ... | 著者 | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | 登録日 | 2009-06-03 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
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3HOX
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![BU of 3hox by Molmil](/molmil-images/mine/3hox) | Complete RNA polymerase II elongation complex V | 分子名称: | 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*AP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... | 著者 | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | 登録日 | 2009-06-03 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
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3HOU
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![BU of 3hou by Molmil](/molmil-images/mine/3hou) | Complete RNA polymerase II elongation complex I with a T-U mismatch | 分子名称: | 5'-D(*A*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*CP*A*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*U*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*U)-3', ... | 著者 | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | 登録日 | 2009-06-03 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
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3HOZ
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![BU of 3hoz by Molmil](/molmil-images/mine/3hoz) | Complete RNA polymerase II elongation complex IV with a T-U mismatch and a frayed RNA 3'-guanine | 分子名称: | 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*CP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*G)-3', ... | 著者 | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | 登録日 | 2009-06-03 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
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