6S53
 
 | | Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ... | | 著者 | Kiss, L, Boland, A, Neuhaus, D, James, L.C. | | 登録日 | 2019-06-30 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Nat Commun, 10, 2019
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3K9P
 | | The crystal structure of E2-25K and ubiquitin complex | | 分子名称: | Ubiquitin, Ubiquitin-conjugating enzyme E2 K | | 著者 | Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H. | | 登録日 | 2009-10-16 | | 公開日 | 2010-09-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285, 2010
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4X57
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5AIE
 | | Not4 ring domain in complex with Ubc4 | | 分子名称: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 4, UBIQUITIN-CONJUGATING ENZYME E2 4, ZINC ION | | 著者 | Bhaskar, V, Basquin, J, Conti, E. | | 登録日 | 2015-02-12 | | 公開日 | 2015-04-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Architecture of the Ubiquitylation Module of the Yeast Ccr4-not Complex.
Structure, 23, 2015
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1A3S
 | | HUMAN UBC9 | | 分子名称: | UBC9 | | 著者 | Naismith, J.H, Giraud, M. | | 登録日 | 1998-01-23 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of ubiquitin-conjugating enzyme 9 displays significant differences with other ubiquitin-conjugating enzymes which may reflect its specificity for sumo rather than ubiquitin.
Acta Crystallogr.,Sect.D, 54, 1998
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7R71
 | | Crystal Structure of the UbArk2C-UbcH5b~Ub complex | | 分子名称: | Ubiquitin, Ubiquitin,E3 ubiquitin-protein ligase RNF165, Ubiquitin-conjugating enzyme E2 D2, ... | | 著者 | Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L. | | 登録日 | 2021-06-24 | | 公開日 | 2022-03-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C.
Nat Commun, 13, 2022
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6UMP
 | | Crystal structure of MavC in complex with substrate mimic in P65 space group | | 分子名称: | MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N | | 著者 | Puvar, K, Iyer, S, Luo, Z.Q, Das, C. | | 登録日 | 2019-10-10 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
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2XWU
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2H2Y
 | | Crystal structure of ubiquitin conjugating enzyme E2 from plasmodium falciparum | | 分子名称: | Ubiquitin-conjugating enzyme | | 著者 | Qiu, W, Dong, A, Zhao, Y, Lew, J, Kozieradski, I, Sundararajan, E, Melone, M, Wasney, G, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | | 登録日 | 2006-05-19 | | 公開日 | 2006-06-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
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2NVU
 | | Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltose binding protein/NEDD8-activating enzyme E1 catalytic subunit chimera, ... | | 著者 | Huang, D.T, Hunt, H.W, Zhuang, M, Ohi, M.D, Holton, J.M, Schulman, B.A. | | 登録日 | 2006-11-13 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
Nature, 445, 2007
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9B5E
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6FGA
 | | Crystal structure of TRIM21 E3 ligase, RING domain in complex with its cognate E2 conjugating enzyme UBE2E1 | | 分子名称: | E3 ubiquitin-protein ligase TRIM21, GLYCEROL, Ubiquitin-conjugating enzyme E2 E1, ... | | 著者 | Anandapadamanaban, M, Moche, M, Sunnerhagen, M. | | 登録日 | 2018-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | E3 ubiquitin-protein ligase TRIM21-mediated lysine capture by UBE2E1 reveals substrate-targeting mode of a ubiquitin-conjugating E2.
J.Biol.Chem., 294, 2019
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5HPT
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5JNE
 | | E2-SUMO-Siz1 E3-SUMO-PCNA complex | | 分子名称: | E3 SUMO-protein ligase SIZ1,Ubiquitin-like protein SMT3, GLYCEROL, Proliferating cell nuclear antigen, ... | | 著者 | Lima, C.D, Streich Jr, F.C. | | 登録日 | 2016-04-29 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Capturing a substrate in an activated RING E3/E2-SUMO complex.
Nature, 536, 2016
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5NKZ
 | | Crystal structure of H. polymorpha ubiquitin conjugating enzyme Pex4p in complex with soluble domain of Pex22p | | 分子名称: | Peroxin 22, Ubiquitin-conjugating enzyme E2-21 kDa | | 著者 | Danda, N, Lunev, S, Ali, A, Groves, M.R, Williams, C. | | 登録日 | 2017-04-03 | | 公開日 | 2018-01-24 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.
Biochem. Biophys. Res. Commun., 496, 2018
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8ODR
 | | Mimetic of UBC9-SUMO1 | | 分子名称: | SULFATE ION, SUMO-conjugating enzyme UBC9, Small ubiquitin-related modifier 1 | | 著者 | Coste, F, Goffinont, S, Suskiewicz, M.J. | | 登録日 | 2023-03-09 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural insights into the regulation of the human E2∼SUMO conjugate through analysis of its stable mimetic.
J.Biol.Chem., 299, 2023
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6KL4
 | | Crystal structure of MavC-UBE2N-Ub | | 分子名称: | MavC, Ub, Ubiquitin-conjugating enzyme E2 N | | 著者 | Ouyang, S, Guan, H. | | 登録日 | 2019-07-29 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC.
Adv Sci, 7, 2020
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9B5J
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1FBV
 | | STRUCTURE OF A CBL-UBCH7 COMPLEX: RING DOMAIN FUNCTION IN UBIQUITIN-PROTEIN LIGASES | | 分子名称: | SIGNAL TRANSDUCTION PROTEIN CBL, SULFATE ION, UBIQUITIN-CONJUGATING ENZYME E12-18 KDA UBCH7, ... | | 著者 | Zheng, N, Wang, P, Jeffrey, P.D, Pavletich, N.P. | | 登録日 | 2000-07-17 | | 公開日 | 2000-08-30 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases.
Cell(Cambridge,Mass.), 102, 2000
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1Q34
 | | Crystal structures of two UBC (E2) enzymes of the ubiquitin-conjugating system in Caenorhabditis elegans | | 分子名称: | Ubiquitin-conjugating enzyme E2-21.5 kDa | | 著者 | Schormann, N, Lin, G, Li, S, Symersky, J, Qiu, S, Finley, J, Luo, D, Stanton, A, Carson, M, Luo, M, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2003-07-28 | | 公開日 | 2003-08-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of two UBC (E2) enzymes of the ubiquitin-conjugating system in Caenorhabditis elegans
To be Published
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2C2V
 | | Crystal structure of the CHIP-UBC13-UEV1a complex | | 分子名称: | STIP1 homology and U box-containing protein 1, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 1 | | 著者 | Zhang, M, Roe, S.M, Pearl, L.H. | | 登録日 | 2005-09-30 | | 公開日 | 2005-11-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex.
Mol. Cell, 20, 2005
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6QH3
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6CP2
 | | SidC in complex with UbcH7~Ub | | 分子名称: | Polyubiquitin-B, SidC, Ubiquitin-conjugating enzyme E2 L3 | | 著者 | Wasilko, D.J, Huang, Q, Mao, Y. | | 登録日 | 2018-03-13 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Insights into the ubiquitin transfer cascade catalyzed by theLegionellaeffector SidC.
Elife, 7, 2018
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2OXQ
 | | Structure of the UbcH5 :CHIP U-box complex | | 分子名称: | CHLORIDE ION, STIP1 homology and U-Box containing protein 1, Ubiquitin-conjugating enzyme E2D 1 | | 著者 | Xu, Z, Nix, J.C, Devlin, K.I, Misra, S. | | 登録日 | 2007-02-20 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes.
Bmc Struct.Biol., 8, 2008
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6KFP
 | | Crystal structure of MavC ternary complex | | 分子名称: | MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N | | 著者 | Mu, Y, Wang, Y, Han, Y, Li, D, Feng, Y. | | 登録日 | 2019-07-08 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
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