4H2G
 
 | | Human ecto-5'-nucleotidase (CD73): crystal form II (open) in complex with adenosine | | 分子名称: | 5'-nucleotidase, ADENOSINE, CALCIUM ION, ... | | 著者 | Straeter, N, Knapp, K.M, Zebisch, M, Pippel, J. | | 登録日 | 2012-09-12 | | 公開日 | 2012-11-28 | | 最終更新日 | 2012-12-26 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal Structure of the Human Ecto-5'-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling.
Structure, 20, 2012
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4HD0
 | | Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair | | 分子名称: | DNA double-strand break repair protein Mre11, MANGANESE (II) ION | | 著者 | Limbo, O, Moiani, D, Kertokalio, A, Wyman, C, Tainer, J.A, Russell, P. | | 登録日 | 2012-10-01 | | 公開日 | 2012-10-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
Nucleic Acids Res., 40, 2012
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3V4Y
 | | Crystal Structure of the first Nuclear PP1 holoenzyme | | 分子名称: | GLYCEROL, MANGANESE (II) ION, Nuclear inhibitor of protein phosphatase 1, ... | | 著者 | Page, R, Peti, W, O'Connell, N.E, Nichols, S. | | 登録日 | 2011-12-15 | | 公開日 | 2012-10-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | | 主引用文献 | The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme.
Structure, 20, 2012
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4H1S
 | | Crystal Structure of a Truncated Soluble form of Human CD73 with Ecto-5'-Nucleotidase activity | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-nucleotidase, PHOSPHATE ION, ... | | 著者 | Heuts, D.P, Weissenborn, M.J, Olkhov, R.V, Shaw, A.M, Levy, C.W, Scrutton, N.S. | | 登録日 | 2012-09-11 | | 公開日 | 2012-10-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a soluble form of human CD73 with ecto-5'-nucleotidase activity.
Chembiochem, 13, 2012
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4G9J
 | | Protein Ser/Thr phosphatase-1 in complex with cell-permeable peptide | | 分子名称: | MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, synthetic peptide | | 著者 | Sukackaite, R, Chatterjee, J, Beullens, M, Bollen, M, Koehn, M, Hart, D.J. | | 登録日 | 2012-07-24 | | 公開日 | 2012-09-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Development of a Peptide that Selectively Activates Protein Phosphatase-1 in Living Cells.
Angew.Chem.Int.Ed.Engl., 51, 2012
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4DT2
 | | Crystal structure of red kidney bean purple acid phosphatase in complex with Maybridge fragment CC27209 | | 分子名称: | (2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)methanol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Feder, D, Hussein, W.M, Clayton, D.J, Kan, M, Schenk, G, McGeary, R.P, Guddat, L.W. | | 登録日 | 2012-02-20 | | 公開日 | 2012-09-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics.
Chem.Biol.Drug Des., 80, 2012
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4DSY
 | | Crystal structure of red kidney bean purple acid phosphatase in complex with Maybridge fragment CC24201 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-phenylpyridine-3-carboxylic acid, ... | | 著者 | Feder, D, Hussein, W.M, Clayton, D.J, Kan, M, Schenk, G, McGeary, R.P, Guddat, L.W. | | 登録日 | 2012-02-20 | | 公開日 | 2012-09-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics.
Chem.Biol.Drug Des., 80, 2012
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4FCX
 | | S.pombe Mre11 apoenzym | | 分子名称: | DNA repair protein rad32, MANGANESE (II) ION | | 著者 | Schiller, C.B, Lammens, K, Hopfner, K.P. | | 登録日 | 2012-05-25 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
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4FBW
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4FBQ
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4FBK
 | | Crystal structure of a covalently fused Nbs1-Mre11 complex with one manganese ion per active site | | 分子名称: | DNA repair and telomere maintenance protein nbs1,DNA repair protein rad32 CHIMERIC PROTEIN, MANGANESE (II) ION, SULFATE ION | | 著者 | Schiller, C.B, Lammens, K, Hopfner, K.P. | | 登録日 | 2012-05-23 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.379 Å) | | 主引用文献 | Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
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3TGH
 | | GAP50 the anchor in the inner membrane complex of Plasmodium | | 分子名称: | COBALT (II) ION, DIMETHYL SULFOXIDE, Glideosome-associated protein 50, ... | | 著者 | Bosch, J, Paige, M.H, Vaidya, A, Bergman, L, Hol, W.G.J. | | 登録日 | 2011-08-17 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum.
J.Struct.Biol., 178, 2012
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3ZTV
 | | Structure of Haemophilus influenzae NAD nucleotidase (NadN) | | 分子名称: | ADENOSINE, GLYCEROL, NAD NUCLEOTIDASE, ... | | 著者 | Garavaglia, S, Bruzzone, S, Cassani, C, Canella, L, Allegrone, G, Sturla, L, Mannino, E, Millo, E, De Flora, A, Rizzi, M. | | 登録日 | 2011-07-12 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The High-Resolution Crystal Structure of Periplasmic Haemophilus Influenzae Nad Nucleotidase Reveals a Novel Enzymatic Function of Human Cd73 Related to Nad Metabolism.
Biochem.J., 441, 2012
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3ZU0
 | | Structure of Haemophilus influenzae NAD nucleotidase (NadN) | | 分子名称: | NAD NUCLEOTIDASE, PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... | | 著者 | Garavaglia, S, Bruzzone, S, Cassani, C, Canella, L, Allegrone, G, Sturla, L, Mannino, E, Millo, E, De Flora, A, Rizzi, M. | | 登録日 | 2011-07-13 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | The High-Resolution Crystal Structure of Periplasmic Haemophilus Influenzae Nad Nucleotidase Reveals a Novel Enzymatic Function of Human Cd73 Related to Nad Metabolism.
Biochem.J., 441, 2012
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3T1I
 | | Crystal Structure of Human Mre11: Understanding Tumorigenic Mutations | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Double-strand break repair protein MRE11A, GLYCEROL, ... | | 著者 | Park, Y.B, Chae, J, Kim, Y, Cho, Y. | | 登録日 | 2011-07-22 | | 公開日 | 2011-11-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of human mre11: understanding tumorigenic mutations
Structure, 19, 2011
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3THN
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3THO
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3RL3
 | | Rat metallophosphodiesterase MPPED2 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GUANOSINE-5'-MONOPHOSPHATE, ... | | 著者 | Podobnik, M, Dermol, U. | | 登録日 | 2011-04-19 | | 公開日 | 2011-08-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
J.Mol.Biol., 412, 2011
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3RL4
 | | Rat metallophosphodiesterase MPPED2 G252H Mutant | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GUANOSINE-5'-MONOPHOSPHATE, ... | | 著者 | Podobnik, M, Dermol, U. | | 登録日 | 2011-04-19 | | 公開日 | 2011-08-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
J.Mol.Biol., 412, 2011
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3RL5
 | | Rat metallophosphodiesterase MPPED2 H67R Mutant | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Metallophosphoesterase MPPED2, ... | | 著者 | Podobnik, M, Dermol, U. | | 登録日 | 2011-04-19 | | 公開日 | 2011-08-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
J.Mol.Biol., 412, 2011
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3AV0
 | | Crystal structure of Mre11-Rad50 bound to ATP S | | 分子名称: | DNA double-strand break repair protein mre11, DNA double-strand break repair rad50 ATPase, GLYCEROL, ... | | 著者 | Lim, H.S, Kim, J.S, Cho, Y. | | 登録日 | 2011-02-18 | | 公開日 | 2011-05-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal Structure of the Mre11-Rad50-ATP S Complex: Understanding the Interplay between Mre11 and Rad50
To be Published
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3AUZ
 | | Crystal structure of Mre11 with manganese | | 分子名称: | DNA double-strand break repair protein mre11, GLYCEROL, MANGANESE (II) ION | | 著者 | Park, Y.B, Cho, Y. | | 登録日 | 2011-02-18 | | 公開日 | 2011-05-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.206 Å) | | 主引用文献 | Crystal Structure of the Mre11-Rad50-ATP S Complex: Understanding the Interplay between Mre11 and Rad50
To be Published
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3QG5
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2XMO
 | | The crystal structure of Lmo2642 | | 分子名称: | CALCIUM ION, FE (III) ION, LMO2642 PROTEIN, ... | | 著者 | Jeong, J.H, Kim, Y.G. | | 登録日 | 2010-07-28 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Functional Analysis of the Lmo2642 Cyclic Nucleotide Phosphodiesterase from Listeria Monocytogenes.
Proteins, 79, 2011
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3P71
 | | Crystal structure of the complex of LCMT-1 and PP2A | | 分子名称: | 5'-{[(3S)-3-amino-3-carboxypropyl](ethyl)amino}-5'-deoxyadenosine, DI(HYDROXYETHYL)ETHER, Leucine carboxyl methyltransferase 1, ... | | 著者 | Xing, Y, Stanevich, V, Satyshur, K.A, Jiang, L. | | 登録日 | 2010-10-11 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The Structural Basis for Tight Control of PP2A Methylation and Function by LCMT-1.
Mol.Cell, 41, 2011
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