3T1I

Crystal Structure of Human Mre11: Understanding Tumorigenic Mutations

Summary for 3T1I

• Entry DOI: 10.2210/pdb3t1i/pdb
• Descriptor: Double-strand break repair protein MRE11A, MANGANESE (II) ION, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (5 entities in total)
• Functional Keywords: dna repair, mrn complex, metallophosphatase, exonuclease, endonuclease, rad50, nbs1, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (By similarity): P49959
• Total number of polymer chains: 4
• Total formula weight: 201428.71

Authors

Park, Y.B.,Chae, J.,Kim, Y.,Cho, Y. (deposition date: 2011-07-22, release date: 2011-11-30)

• Primary citation: Park, Y.B.,Chae, J.,Kim, Y.,Cho, Y.; Crystal structure of human mre11: understanding tumorigenic mutations; Structure, 19:1591-1602, 2011; PubMed: 22078559; DOI: 10.1016/j.str.2011.09.010

Experimental method

X-RAY DIFFRACTION (3 Å)