4FBK

Crystal structure of a covalently fused Nbs1-Mre11 complex with one manganese ion per active site

Summary for 4FBK

Entry DOI	10.2210/pdb4fbk/pdb
Related	4FBQ 4FBW 4FCX
Descriptor	DNA repair and telomere maintenance protein nbs1,DNA repair protein rad32 CHIMERIC PROTEIN, SULFATE ION, MANGANESE (II) ION, ... (4 entities in total)
Functional Keywords	dna double-strand break repair, nuclease, schizosaccharomyces pombe, hydrolase, protein binding
Biological source	Schizosaccharomyces pombe More
Cellular location	Nucleus : Q09683
Total number of polymer chains	2
Total formula weight	107197.96
Authors	Schiller, C.B.,Lammens, K.,Hopfner, K.P. (deposition date: 2012-05-23, release date: 2012-06-20, Last modification date: 2024-02-28)
Primary citation	Schiller, C.B.,Lammens, K.,Guerini, I.,Coordes, B.,Feldmann, H.,Schlauderer, F.,Mockel, C.,Schele, A.,Strasser, K.,Jackson, S.P.,Hopfner, K.P. Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling. Nat.Struct.Mol.Biol., 19:693-700, 2012 Cited by PubMed: 22705791 DOI: 10.1038/nsmb.2323 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.379 Å)

Structure validation