Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004519 | molecular_function | endonuclease activity |
A | 0004520 | molecular_function | DNA endonuclease activity |
A | 0005634 | cellular_component | nucleus |
A | 0006302 | biological_process | double-strand break repair |
A | 0008296 | molecular_function | 3'-5'-DNA exonuclease activity |
A | 0016787 | molecular_function | hydrolase activity |
A | 0030145 | molecular_function | manganese ion binding |
A | 0030870 | cellular_component | Mre11 complex |
B | 0004519 | molecular_function | endonuclease activity |
B | 0004520 | molecular_function | DNA endonuclease activity |
B | 0005634 | cellular_component | nucleus |
B | 0006302 | biological_process | double-strand break repair |
B | 0008296 | molecular_function | 3'-5'-DNA exonuclease activity |
B | 0016787 | molecular_function | hydrolase activity |
B | 0030145 | molecular_function | manganese ion binding |
B | 0030870 | cellular_component | Mre11 complex |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE SO4 A 1501 |
Chain | Residue |
A | ASP1065 |
A | HOH1693 |
A | ILE1066 |
A | PHE1067 |
A | HIS1131 |
A | GLY1132 |
A | HIS1134 |
A | LEU1146 |
A | HOH1648 |
A | HOH1656 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 1502 |
Chain | Residue |
A | LYS1071 |
A | HOH1618 |
B | SER1073 |
B | ARG1074 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 1503 |
Chain | Residue |
A | SER1073 |
A | ARG1074 |
A | HOH1607 |
B | LYS1071 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MN A 1504 |
Chain | Residue |
A | ASP1025 |
A | HIS1027 |
A | ASP1065 |
A | HIS1250 |
A | HIS1252 |
site_id | AC5 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 B 1501 |
Chain | Residue |
B | ASP1065 |
B | ILE1066 |
B | PHE1067 |
B | HIS1131 |
B | GLY1132 |
B | HIS1134 |
B | LEU1146 |
B | HOH1640 |
B | HOH1657 |
site_id | AC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MN B 1502 |
Chain | Residue |
B | ASP1025 |
B | HIS1027 |
B | ASP1065 |
B | HIS1250 |
B | HIS1252 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor => ECO:0000255|PIRSR:PIRSR000882-1 |
Chain | Residue | Details |
A | HIS1134 | |
B | HIS1134 | |
Chain | Residue | Details |
A | ASP1025 | |
B | ASP1065 | |
B | ASN1133 | |
B | HIS1222 | |
B | HIS1250 | |
B | HIS1252 | |
A | HIS1027 | |
A | ASP1065 | |
A | ASN1133 | |
A | HIS1222 | |
A | HIS1250 | |
A | HIS1252 | |
B | ASP1025 | |
B | HIS1027 | |