PDB: 1712 件ウェブページステータス検索Chemie searchBIRD

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6UCI	Transcription factor DeltaFosB bZIP domain self-assembly, oxidized form 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Protein fosB 著者 Yin, Z, Machius, M, Rudenko, G. 登録日 2019-09-16 公開日 2020-01-15 最終更新日 2020-07-01 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Self-assembly of the bZIP transcription factor Delta FosB. Curr Res Struct Biol, 2, 2020
1UEF	Crystal Structure of Dok1 PTB Domain Complex 分子名称: 13-mer peptide from Proto-oncogene tyrosine-protein kinase receptor ret, Docking protein 1 著者 Shi, N, Ye, S, Liu, Y, Zhou, W, Ding, Y, Lou, Z, Qiang, B, Yan, J, Rao, Z. 登録日 2003-05-14 公開日 2004-05-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain J.Biol.Chem., 279, 2004
1P5T	Crystal Structure of Dok1 PTB Domain 分子名称: Docking protein 1 著者 Shi, N, Ye, S, Liu, Y, Zhou, W, Ding, Y, Lou, Z, Qiang, B, Yuan, J, Rao, Z. 登録日 2003-04-28 公開日 2004-02-17 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain J.BIOL.CHEM., 279, 2004
7QU1	Machupo virus GP1 glycoprotein in complex with Fab fragment of antibody MAC1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab MAC1 heavy chain, Fab MAC1 light chain, ... 著者 Ng, W.M, Sahin, M, Krumm, S.A, Seow, J, Zeltina, A, Harlos, K, Paesen, G, Pinschewer, D.D, Doores, K.J, Bowden, T.A. 登録日 2022-01-17 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies. Mbio, 13, 2022
1PGT	CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE S-TRANSFERASE P1-1[V104] COMPLEXED WITH S-HEXYLGLUTATHIONE 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE, S-HEXYLGLUTATHIONE 著者 Ji, X. 登録日 1997-02-17 公開日 1997-09-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure and function of the xenobiotic substrate-binding site and location of a potential non-substrate-binding site in a class pi glutathione S-transferase. Biochemistry, 36, 1997
7QU2	Junin virus GP1 glycoprotein in complex with Fab fragment of antibody JUN1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab JUN1 heavy chain, ... 著者 Ng, W.M, Sahin, M, Krumm, S.A, Seow, J, Zeltina, A, Harlos, K, Paesen, G, Pinschewer, D.D, Doores, K.J, Bowden, T.A. 登録日 2022-01-17 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies. Mbio, 13, 2022
1PX6	A folding mutant of human class pi glutathione transferase, created by mutating aspartate 153 of the wild-type protein to asparagine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Glutathione S-transferase P 著者 Kong, G.K.-W, Polekhina, G, McKinstry, W.J, Parker, M.W, Dragani, B, Aceto, A, Paludi, D, Principe, D.R, Mannervik, B, Stenberg, G. 登録日 2003-07-02 公開日 2003-07-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The multi-functional role of a highly conserved aspartic acid residue in glutathione transferase P1-1 To be Published
1PX7	A folding mutant of human class pi glutathione transferase, created by mutating aspartate 153 of the wild-type protein to glutamate 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLUTATHIONE, ... 著者 Kong, G.K.-W, Polekhina, G, McKinstry, W.J, Parker, M.W, Dragani, B, Aceto, A, Paludi, D, Principe, D.R, Mannervik, B, Stenberg, G. 登録日 2003-07-02 公開日 2003-07-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 The multi-functional role of a highly conserved aspartic acid residue in glutathione transferase P1-1 To be Published
1OZJ	Crystal structure of Smad3-MH1 bound to DNA at 2.4 A resolution 分子名称: SMAD 3, Smad binding element, ZINC ION 著者 Chai, J, Wu, J.-W, Yan, N, Massague, J, Pavletich, N.P, Shi, Y. 登録日 2003-04-09 公開日 2004-03-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Features of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA binding. J.Biol.Chem., 278, 2003
7S1N	N-Aromatic-Substituted Indazole Derivatives as Brain Penetrant and Orally Bioavailable JNK3 Inhibitors 分子名称: 4-[5-(2-chloro-6-fluoroanilino)-6-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl]-N-(oxetan-3-yl)thiophene-2-carboxamide, Mitogen-activated protein kinase 10 著者 Park, H. 登録日 2021-09-02 公開日 2021-11-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 N -Aromatic-Substituted Indazole Derivatives as Brain-Penetrant and Orally Bioavailable JNK3 Inhibitors. Acs Med.Chem.Lett., 12, 2021
1KBN	Glutathione transferase mutant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, GLYCEROL, ... 著者 Rossjohn, J, Parker, M.W. 登録日 2001-11-06 公開日 2003-11-11 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Glutathione transferase mutant To be Published
1LBK	Crystal structure of a recombinant glutathione transferase, created by replacing the last seven residues of each subunit of the human class pi isoenzyme with the additional C-terminal helix of human class alpha isoenzyme 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Glutathione S-transferase class pi chimaera (CODA), ... 著者 Kong, G.K.W, Micaloni, C, Mazzetti, A.P, Nuccetelli, M, Antonini, G, Stella, L, McKinstry, W.J, Polekhina, G, Rossjohn, J, Federici, G, Ricci, G, Parker, M.W, Lo Bello, M. 登録日 2002-04-04 公開日 2002-04-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences. J.Mol.Biol., 325, 2003
1MD4	A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to valine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, pi glutathione transferase 著者 Kong, G.K.-W, Dragani, B, Aceto, A, Cocco, R, Mannervik, B, Stenberg, G, McKinstry, W.J, Polekhina, G, Parker, M.W. 登録日 2002-08-06 公開日 2002-08-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1 J.Biol.Chem., 278, 2003
2GSS	HUMAN GLUTATHIONE S-TRANSFERASE P1-1 IN COMPLEX WITH ETHACRYNIC ACID 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ETHACRYNIC ACID, GLUTATHIONE S-TRANSFERASE P1-1, ... 著者 Oakley, A.J, Rossjohn, J, Parker, M.W. 登録日 1996-10-29 公開日 1997-11-12 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate. Biochemistry, 36, 1997
2J9H	Crystal structure of human glutathione-S-transferase P1-1 cys-free mutant in complex with S-hexylglutathione at 2.4 A resolution 分子名称: GLUTATHIONE S-TRANSFERASE P, S-HEXYLGLUTATHIONE 著者 Tars, K, Hegazy, U.M, Hellman, U, Mannervik, B. 登録日 2006-11-08 公開日 2006-11-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Modulating Catalytic Activity by Unnatural Amino Acid Residues in a Gsh-Binding Loop of Gst P1-1. J.Mol.Biol., 376, 2008
5DAL	Crystal Structure of human Glutathione Transferase Pi complexed with a metalloid in the presence of Glutathione 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Di-glutathione-PhenylArsine, GLUTATHIONE, ... 著者 Parker, L.J, Parker, M.W, Morton, C.J. 登録日 2015-08-20 公開日 2016-12-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics To Be Published
5DJL	Structure of WT Human Glutathione Transferase in complex with cisplatin in the presence of glutathione. 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONATE ION, ... 著者 Parker, L.J. 登録日 2015-09-02 公開日 2016-11-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A structure-based mechanism of cisplatin resistance mediated by Glutathione Transferase P1-1 Proc.Natl.Acad.Sci.USA, 2019
5DDL	Crystal Structure of WT Human Glutathione Transferase Pi soaked with a metalloid then back-soaked with glutathione 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Di-glutathione-PhenylArsine, ... 著者 Parker, L.J, Parker, M.W, Morton, C.J. 登録日 2015-08-25 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics To Be Published
5DAK	Crystal Structure of human Glutathione Transferase Pi complexed with a metalloid in the absence of Glutathione 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ARSENIC, Glutathione S-transferase P 著者 Parker, L.J, Parker, M.W, Morton, C.J. 登録日 2015-08-20 公開日 2016-12-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics To Be Published
5DCG	Crystal Structure of WT Apo Human Glutathione Transferase Pi 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Glutathione S-transferase P, ... 著者 Parker, L.J, Parker, M.W, Morton, C.J. 登録日 2015-08-24 公開日 2016-12-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics To Be Published
5DJM	Structure of WT Human Glutathione Transferase in complex with cisplatin in the absence of glutathione. 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Glutathione S-transferase P, PLATINUM (II) ION 著者 Parker, L.J. 登録日 2015-09-02 公開日 2016-11-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A structure-based mechanism of cisplatin resistance mediated by Glutathione Transferase P1-1 Proc.Natl.Acad.Sci.USA, 2019
2GLR	MOLECULAR STRUCTURE AT 1.8 ANGSTROMS OF MOUSE LIVER CLASS PI GLUTATHIONE S-TRANSFERASE COMPLEXED WITH S-(P-NITROBENZYL)GLUTATHIONE AND OTHER INHIBITORS 分子名称: GLUTATHIONE S-TRANSFERASE YFYF, S-HEXYLGLUTATHIONE 著者 Parraga, A, Garcia-Saez, I, Coll, M. 登録日 1994-05-04 公開日 1994-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular structure at 1.8 A of mouse liver class pi glutathione S-transferase complexed with S-(p-nitrobenzyl)glutathione and other inhibitors. J.Mol.Biol., 237, 1994
3U88	Crystal structure of human menin in complex with MLL1 and LEDGF 分子名称: (4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol, CHOLIC ACID, GLYOXYLIC ACID, ... 著者 Huang, J, Wan, B, Lei, M. 登録日 2011-10-16 公開日 2012-02-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature, 482, 2012
3TTJ	Crystal Structure of JNK3 complexed with CC-359, a JNK inhibitor for the prevention of ischemia-reperfusion injury 分子名称: 9-cyclopentyl-N~8~-(2-fluorophenyl)-N~2~-(4-methoxyphenyl)-9H-purine-2,8-diamine, Mitogen-activated protein kinase 10 著者 Plantevin-Krenitsky, V, Delgado, M, Nadolny, L, Sahasrabudhe, K, Ayala, S, Clareen, S, Hilgraf, R, Albers, R, Kois, A, Hughes, K, Wright, J, Nowakowski, J, Sudbeck, E, Ghosh, S, Bahmanyar, S, Chamberlain, P, Muir, J, Cathers, B.E, Giegel, D, Xu, L, Celeridad, M, Moghaddam, M, Khatsenko, O, Omholt, P, Katz, J, Pai, S, Fan, R, Tang, Y, Shirley, M.A, Benish, B, Blease, K, Raymon, H, Bhagwat, S, Bennett, B, Satoh, Y. 登録日 2011-09-14 公開日 2012-01-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury. Bioorg.Med.Chem.Lett., 22, 2012
3U84	Crystal Structure of Human Menin 分子名称: Menin 著者 Huang, J, Wan, B, Lei, M. 登録日 2011-10-15 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature, 482, 2012

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