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6DBT
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BU of 6dbt by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs
分子名称: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBU
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BU of 6dbu by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs
分子名称: CALCIUM ION, Forward strand RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBV
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BU of 6dbv by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs
分子名称: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4.29 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBO
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BU of 6dbo by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs
分子名称: CALCIUM ION, Forward strand of substrate RSS DNA, Recombination activating gene 1 - MBP chimera, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBW
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BU of 6dbw by Molmil
Cryo-EM structure of RAG in complex with 12-RSS substrate DNA
分子名称: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBX
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BU of 6dbx by Molmil
Cryo-EM structure of RAG in complex with 12-RSS substrate DNA
分子名称: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ...
著者Wu, H, Liao, M, Ru, H, Mi, W.
登録日2018-05-03
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
7UPN
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BU of 7upn by Molmil
Maedi visna virus Vif in complex with CypA and E3 ubiquitin ligase
分子名称: Elongin-B, Elongin-C, Peptidyl-prolyl cis-trans isomerase A, ...
著者Hu, Y, Xiong, Y.
登録日2022-04-16
公開日2023-01-25
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for recruitment of host CypA and E3 ubiquitin ligase by maedi-visna virus Vif.
Sci Adv, 9, 2023
6CVP
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BU of 6cvp by Molmil
Human Aprataxin (Aptx) R199H bound to RNA-DNA, AMP and Zn product complex
分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ...
著者Schellenberg, M.J, Williams, R.S, Tumbale, P.S.
登録日2018-03-28
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease.
EMBO J., 37, 2018
6CVS
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BU of 6cvs by Molmil
Human Aprataxin (Aptx) L248M bound to DNA, AMP and Zn product
分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ...
著者Schellenberg, M.J, Tumbale, P.S, Williams, R.S.
登録日2018-03-28
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease.
EMBO J., 37, 2018
6CVR
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BU of 6cvr by Molmil
Human Aprataxin (Aptx) S242N bound to RNA-DNA, AMP and Zn product complex
分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ...
著者Schellenberg, M.J, Tumbale, P.S, Williams, R.S.
登録日2018-03-28
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease.
EMBO J., 37, 2018
6CVQ
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BU of 6cvq by Molmil
Human Aprataxin (Aptx) H201Q bound to RNA-DNA, AMP and Zn product complex
分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ...
著者Schellenberg, M.J, Tumbale, P.S, Williams, R.S.
登録日2018-03-28
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease.
EMBO J., 37, 2018
6CVO
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BU of 6cvo by Molmil
Human Aprataxin (Aptx) bound to nicked RNA-DNA, AMP and Zn product complex
分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ...
著者Schellenberg, M.J, Tumbale, P.P, Williams, R.S.
登録日2018-03-28
公開日2018-08-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease.
EMBO J., 37, 2018
6CVT
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BU of 6cvt by Molmil
Human Aprataxin (Aptx) V263G bound to RNA-DNA, AMP and Zn product complex
分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ...
著者Schellenberg, M.J, Tumbale, P.S, Williams, R.S.
登録日2018-03-28
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.941 Å)
主引用文献Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease.
EMBO J., 37, 2018
3U7F
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BU of 3u7f by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTCp)
分子名称: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
著者Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
登録日2011-10-13
公開日2011-12-14
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U7G
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BU of 3u7g by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)
分子名称: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
著者Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
登録日2011-10-13
公開日2011-12-14
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U7H
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BU of 3u7h by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTTp)
分子名称: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
著者Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
登録日2011-10-13
公開日2011-12-14
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
4CI1
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BU of 4ci1 by Molmil
Structure of the DDB1-CRBN E3 ubiquitin ligase bound to thalidomide
分子名称: DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Thalidomide, ...
著者Fischer, E.S, Boehm, K, Thoma, N.H.
登録日2013-12-05
公開日2014-07-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide.
Nature, 512, 2014
4M6F
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BU of 4m6f by Molmil
Dimer of the G-Segment Invertase bound to a DNA substrate
分子名称: DNA-invertase, gix site analog
著者Ritacco, C.J, Wang, J, Steitz, T.A.
登録日2013-08-09
公開日2014-03-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.99 Å)
主引用文献Exploiting large non-isomorphous differences for phase determination of a G-segment invertase-DNA complex.
Acta Crystallogr.,Sect.D, 70, 2014
4WHV
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BU of 4whv by Molmil
E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B
分子名称: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ...
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-09-23
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (8.3 Å)
主引用文献RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
J.Biol.Chem., 291, 2016
7LT3
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BU of 7lt3 by Molmil
NHEJ Long-range synaptic complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (30-MER), DNA (31-MER), ...
著者He, Y, Chen, S.
登録日2021-02-18
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis of long-range to short-range synaptic transition in NHEJ.
Nature, 593, 2021
7KZV
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BU of 7kzv by Molmil
Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in closed state
分子名称: DNA (29-MER), E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, ...
著者Wang, S.L, Pavletich, N.P.
登録日2020-12-10
公開日2021-03-10
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
7KZT
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BU of 7kzt by Molmil
Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in intermediate state
分子名称: DNA (22-MER), E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, ...
著者Wang, S.L, Pavletich, N.P.
登録日2020-12-10
公開日2021-03-10
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
7KZS
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BU of 7kzs by Molmil
Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in open state
分子名称: DNA (25-MER), E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, ...
著者Wang, S.L, Pavletich, N.P.
登録日2020-12-10
公開日2021-03-10
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
2ZO2
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BU of 2zo2 by Molmil
Mouse NP95 SRA domain non-specific DNA complex
分子名称: DNA (5'-D(*DAP*DAP*DCP*DTP*DGP*DCP*DGP*DCP*DAP*DGP*DTP*DT)-3'), E3 ubiquitin-protein ligase UHRF1, PHOSPHATE ION
著者Hashimoto, H, Horton, J.R, Cheng, X.
登録日2008-05-05
公開日2008-09-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
Nature, 455, 2008
2ZO0
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BU of 2zo0 by Molmil
mouse NP95 SRA domain DNA specific complex 1
分子名称: DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), E3 ubiquitin-protein ligase UHRF1
著者Hashimoto, H, Horton, J.R, Cheng, X.
登録日2008-05-05
公開日2008-09-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
Nature, 455, 2008

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件を2024-11-06に公開中

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