6DBT
| Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | 分子名称: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBU
| Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | 分子名称: | CALCIUM ION, Forward strand RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBV
| Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | 分子名称: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.29 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBO
| Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | 分子名称: | CALCIUM ION, Forward strand of substrate RSS DNA, Recombination activating gene 1 - MBP chimera, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBW
| Cryo-EM structure of RAG in complex with 12-RSS substrate DNA | 分子名称: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBX
| Cryo-EM structure of RAG in complex with 12-RSS substrate DNA | 分子名称: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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7UPN
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6CVP
| Human Aprataxin (Aptx) R199H bound to RNA-DNA, AMP and Zn product complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... | 著者 | Schellenberg, M.J, Williams, R.S, Tumbale, P.S. | 登録日 | 2018-03-28 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
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6CVS
| Human Aprataxin (Aptx) L248M bound to DNA, AMP and Zn product | 分子名称: | ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ... | 著者 | Schellenberg, M.J, Tumbale, P.S, Williams, R.S. | 登録日 | 2018-03-28 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
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6CVR
| Human Aprataxin (Aptx) S242N bound to RNA-DNA, AMP and Zn product complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... | 著者 | Schellenberg, M.J, Tumbale, P.S, Williams, R.S. | 登録日 | 2018-03-28 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
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6CVQ
| Human Aprataxin (Aptx) H201Q bound to RNA-DNA, AMP and Zn product complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ... | 著者 | Schellenberg, M.J, Tumbale, P.S, Williams, R.S. | 登録日 | 2018-03-28 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
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6CVO
| Human Aprataxin (Aptx) bound to nicked RNA-DNA, AMP and Zn product complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ... | 著者 | Schellenberg, M.J, Tumbale, P.P, Williams, R.S. | 登録日 | 2018-03-28 | 公開日 | 2018-08-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
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6CVT
| Human Aprataxin (Aptx) V263G bound to RNA-DNA, AMP and Zn product complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... | 著者 | Schellenberg, M.J, Tumbale, P.S, Williams, R.S. | 登録日 | 2018-03-28 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.941 Å) | 主引用文献 | Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
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3U7F
| Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTCp) | 分子名称: | Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... | 著者 | Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. | 登録日 | 2011-10-13 | 公開日 | 2011-12-14 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108, 2011
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3U7G
| Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp) | 分子名称: | Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... | 著者 | Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. | 登録日 | 2011-10-13 | 公開日 | 2011-12-14 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108, 2011
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3U7H
| Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTTp) | 分子名称: | Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... | 著者 | Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. | 登録日 | 2011-10-13 | 公開日 | 2011-12-14 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108, 2011
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4CI1
| Structure of the DDB1-CRBN E3 ubiquitin ligase bound to thalidomide | 分子名称: | DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Thalidomide, ... | 著者 | Fischer, E.S, Boehm, K, Thoma, N.H. | 登録日 | 2013-12-05 | 公開日 | 2014-07-16 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide. Nature, 512, 2014
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4M6F
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4WHV
| E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B | 分子名称: | E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ... | 著者 | Hodge, C.D, Edwards, R.A, Glover, J.N.M. | 登録日 | 2014-09-23 | 公開日 | 2015-09-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (8.3 Å) | 主引用文献 | RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment. J.Biol.Chem., 291, 2016
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7LT3
| NHEJ Long-range synaptic complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (30-MER), DNA (31-MER), ... | 著者 | He, Y, Chen, S. | 登録日 | 2021-02-18 | 公開日 | 2021-04-14 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural basis of long-range to short-range synaptic transition in NHEJ. Nature, 593, 2021
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7KZV
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7KZT
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7KZS
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2ZO2
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2ZO0
| mouse NP95 SRA domain DNA specific complex 1 | 分子名称: | DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), E3 ubiquitin-protein ligase UHRF1 | 著者 | Hashimoto, H, Horton, J.R, Cheng, X. | 登録日 | 2008-05-05 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix Nature, 455, 2008
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