PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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9EOW	The 5-terminal stem-loop RNA element of SARS-CoV-2 features highly dynamic structural elements that are sensitive to differences in cellular pH 分子名称: RNA (29-MER) 著者 Wacker, A, Schwalbe, H. 登録日 2024-03-15 公開日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 The 5'-terminal stem-loop RNA element of SARS-CoV-2 features highly dynamic structural elements that are sensitive to differences in cellular pH. Nucleic Acids Res., 2024
9EOU	Crystal Structure of the b1b2 domains from Human Neuropilin-1 in complex with a peptide. 分子名称: Neuropilin-1, Osteopontin 著者 Caing-Carlsson, R, Duelli, A, Walse, B. 登録日 2024-03-15 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis. Pharmacol Res, 205, 2024
9EOQ	Cryo-EM Structure of a 1033 Scaffold Base DNA Origami Nanostructure V4 and TBA 分子名称: DNA (42-MER), DNA (5'-D(P*AP*TP*AP*TP*AP*GP*CP*GP*TP*GP*GP*AP*AP*GP*T)-3') 著者 Ali, K, Georg, K, Volodymyr, M, Johanna, G, Maximilian, N.H, Lukas, K, Simone, C, Hendrik, D. 登録日 2024-03-15 公開日 2024-04-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.5 Å) 主引用文献 Designing Rigid DNA Origami Templates for Molecular Visualization Using Cryo-EM. Nano Lett., 24, 2024
9EOJ	Vertebrate microtubule-capping gamma-tubulin ring complex 分子名称: Gamma-tubulin complex component, Gamma-tubulin complex component 3 homolog, Gamma-tubulin complex component 6, ... 著者 Vermeulen, B.J.A, Pfeffer, S. 登録日 2024-03-15 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (17 Å) 主引用文献 gamma-TuRC asymmetry induces local protofilament mismatch at the RanGTP-stimulated microtubule minus end. Embo J., 43, 2024
9EOH	PHF type tau filament from in vitro V337M mutant 分子名称: Isoform Tau-F of Microtubule-associated protein tau 著者 Qi, C, Lovestam, S, Scheres, S.H.W, Michel, G. 登録日 2024-03-14 公開日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. Biorxiv, 2024
9EOG	PHF type tau filament from R406W mutant 分子名称: Microtubule-associated protein tau 著者 Qi, C, Scheres, S.H.W, Michel, G. 登録日 2024-03-14 公開日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. Biorxiv, 2024
9EOF	Structure of the human INTS5/8/10/15 subcomplex 分子名称: Integrator complex subunit 10, Integrator complex subunit 15, Integrator complex subunit 5, ... 著者 Razew, M, Galej, W.P. 登録日 2024-03-14 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (7.7 Å) 主引用文献 Structural basis of the Integrator complex assembly and association with transcription factors. Mol.Cell, 2024
9EOE	PHF type tau filament from V337M mutant 分子名称: Isoform Tau-F of Microtubule-associated protein tau 著者 Qi, C, Scheres, S.H.W, Michel, G. 登録日 2024-03-14 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. Biorxiv, 2024
9EOC	Structure of the Integrator arm module containing INTS10/13/14 subunits 分子名称: Integrator complex subunit 10, Integrator complex subunit 13, Integrator complex subunit 14, ... 著者 Razew, M, Galej, W.P. 登録日 2024-03-14 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of the Integrator complex assembly and association with transcription factors. Mol.Cell, 2024
9EO9	PHF type tau filament from V337M mutant 分子名称: Isoform Tau-F of Microtubule-associated protein tau 著者 Qi, C, Scheres, S.H.W, Michel, G. 登録日 2024-03-14 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. Biorxiv, 2024
9EO8	X-ray structure of the adduct formed upon reaction of picoplatin with bovine pancreatic ribonuclease (structure D) 分子名称: AMMONIA, CHLORIDE ION, PLATINUM (II) ION, ... 著者 Ferraro, G, Merlino, A. 登録日 2024-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A. Dalton Trans, 53, 2024
9EO7	PHF type tau filament from V337M mutant 分子名称: Isoform Tau-F of Microtubule-associated protein tau 著者 Qi, C, Scheres, S.H.W, Michel, G. 登録日 2024-03-14 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. Biorxiv, 2024
9EO5	X-ray structure of the adduct formed upon reaction of picoplatin with bovine pancreatic ribonuclease (structure C) 分子名称: AMMONIA, PLATINUM (II) ION, Ribonuclease pancreatic 著者 Ferraro, G, Merlino, A. 登録日 2024-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A. Dalton Trans, 53, 2024
9EO4	Outward-open structure of human dopamine transporter bound to cocaine 分子名称: CHLORIDE ION, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ... 著者 Nielsen, J.C, Salomon, K, Kalenderoglou, I.E, Bargmeyer, S, Pape, T, Shahsavar, A, Loland, C.J. 登録日 2024-03-14 公開日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 The molecular basis for cocaine binding to the human dopamine transporter To Be Published
9EO2	X-ray structure of the adduct formed upon reaction of picoplatin with lysozyme (structure B) 分子名称: ACETATE ION, GLYCEROL, Lysozyme C, ... 著者 Ferraro, G, Merlino, A. 登録日 2024-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A. Dalton Trans, 53, 2024
9EO0	Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 分子名称: Programmed cell death 1 ligand 1, SULFATE ION, ~{N}-[3-[3-[[5-[(2-hydroxyethylamino)methyl]pyridin-2-yl]carbonylamino]-2-methyl-phenyl]-2-methyl-phenyl]-5-[[3-(methylsulfonylamino)propylamino]methyl]pyridine-2-carboxamide 著者 Plewka, J, Hec, A, Sitar, T, Holak, T. 登録日 2024-03-14 公開日 2024-06-19 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Nonsymmetrically Substituted 1,1'-Biphenyl-Based Small Molecule Inhibitors of the PD-1/PD-L1 Interaction. Acs Med.Chem.Lett., 15, 2024
9ENZ	X-ray structure of the adduct formed upon reaction of picoplatin with lysozyme (structure A) 分子名称: ACETATE ION, AMMONIA, Lysozyme C, ... 著者 Ferraro, G, Merlino, A. 登録日 2024-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A. Dalton Trans, 53, 2024
9ENQ	HSV-1 DNA polymerase-processivity factor complex in exonuclease state active site with 1-bp DNA mismatch 分子名称: CALCIUM ION, DNA (46-MER), DNA (67-MER), ... 著者 Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. 登録日 2024-03-13 公開日 2024-05-29 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.12 Å) 主引用文献 Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 52, 2024
9ENP	HSV-1 DNA polymerase-processivity factor complex in exonuclease state with 1-bp DNA mismatch 分子名称: CALCIUM ION, DNA (46-MER), DNA (67-MER), ... 著者 Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. 登録日 2024-03-13 公開日 2024-05-29 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.12 Å) 主引用文献 Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 52, 2024
9ENF	Human pseudouridine synthase 3 (PUS3 D118A mutant) and two pre-tRNA-Arg 分子名称: pre-tRNA-Arg, tRNA pseudouridine(38/39) synthase 著者 Lin, T.-Y, Jezowski, J, Glatt, S. 登録日 2024-03-12 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 The molecular basis of tRNA selectivity by human pseudouridine synthase 3 (PUS3) Mol.Cell
9ENE	Human pseudouridine synthase 3 (PUS3 D118A mutant) and two tRNA-Arg 分子名称: tRNA pseudouridine(38/39) synthase, tRNA-Arg 著者 Lin, T.-Y, Jezowski, J, Glatt, S. 登録日 2024-03-12 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.15 Å) 主引用文献 The molecular basis of tRNA selectivity by human pseudouridine synthase 3 (PUS3) Mol.Cell, 2024
9END	Crystal structure of Methanopyrus kandleri malate dehydrogenase mutant 3 分子名称: CHLORIDE ION, Malate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Coquille, S, Roche, J, Girard, E, Madern, D. 登録日 2024-03-12 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Navigating the conformational landscape of an enzyme. Stabilization of a low populated conformer by evolutionary mutations triggers Allostery into a non-allosteric enzyme. To be published
9ENC	Human pseudouridine synthase 3 (PUS3 R116A mutant) and one tRNA-Gln 分子名称: tRNA pseudouridine(38/39) synthase, tRNA-Gln 著者 Lin, T.-Y, Jezowski, J, Glatt, S. 登録日 2024-03-12 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.36 Å) 主引用文献 The molecular basis of tRNA selectivity by human pseudouridine synthase 3 (PUS3) Mol.Cell
9ENB	Human pseudouridine synthase 3 (PUS3 R116A mutant) and two tRNA-Gln 分子名称: MAGNESIUM ION, tRNA pseudouridine(38/39) synthase, tRNA-Gln 著者 Lin, T.-Y, Jezowski, J, Glatt, S. 登録日 2024-03-12 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 The molecular basis of tRNA selectivity by human pseudouridine synthase 3 (PUS3) Mol.Cell
9EN6	Crystal structure of RNA G2C4 repeats - native model pH 6.5 分子名称: MAGNESIUM ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3') 著者 Mateja-Pluta, M, Kiliszek, A. 登録日 2024-03-12 公開日 2024-05-01 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (0.918 Å) 主引用文献 Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand. Nucleic Acids Res., 52, 2024

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