4OQ8
| Satellite Tobacco Mosaic Virus Refined to 1.4 A Resolution using icosahedral constraints | 分子名称: | Coat protein, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Larson, S.B, Day, J.S, McPherson, A. | 登録日 | 2014-02-07 | 公開日 | 2014-09-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Satellite tobacco mosaic virus refined to 1.4 angstrom resolution. Acta Crystallogr.,Sect.D, 70, 2014
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4XMM
| Structure of the yeast coat nucleoporin complex, space group C2 | 分子名称: | Antibody 57 heavy chain, Antibody 57 light chain, Nucleoporin NUP120, ... | 著者 | Stuwe, T, Correia, A.R, Lin, D.H, Paduch, M, Lu, V.T, Kossiakoff, A.A, Hoelz, A. | 登録日 | 2015-01-14 | 公開日 | 2015-03-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (7.384 Å) | 主引用文献 | Nuclear pores. Architecture of the nuclear pore complex coat. Science, 347, 2015
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5K3M
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4XAO
| Crystal structure of the hPXR-LBD obtained in presence of the pesticide trans-nonachlor | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ISOPROPYL ALCOHOL, Nuclear receptor subfamily 1 group I member 2 | 著者 | Delfosse, V, Huet, T, Bourguet, W. | 登録日 | 2014-12-15 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds. Nat Commun, 6, 2015
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6HWT
| Crystal structure of p38alpha in complex with a reduced photoswitchable 2-Azothiazol-based Inhibitor (compound 31) | 分子名称: | 3-(2,5-dimethoxyphenyl)-~{N}-[4-[4-(4-fluorophenyl)-2-(2-phenylhydrazinyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | 著者 | Mueller, M.P, Rauh, D. | 登録日 | 2018-10-15 | 公開日 | 2019-04-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | 2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach. Photochem. Photobiol. Sci., 18, 2019
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6KPD
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4FV5
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4FV8
| Crystal Structure of the ERK2 complexed with E63 | 分子名称: | 1,2-ETHANEDIOL, 6-({4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]-5-(phenylamino)pyrimidin-2-yl}amino)-1,2-dihydro-3H-indazol-3-one, Mitogen-activated protein kinase 1, ... | 著者 | Kang, Y.N, Stuckey, J.A, Xie, X. | 登録日 | 2012-06-29 | 公開日 | 2012-08-29 | 最終更新日 | 2014-09-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the ERK2 complexed with E63 TO BE PUBLISHED
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5K1B
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4A75
| The Lin28b Cold shock domain in complex with hexathymidine. | 分子名称: | 5'-D(*TP*TP*TP*TP*TP*TP)-3', LIN28 COLD SHOCK DOMAIN, THIOCYANATE ION | 著者 | Mayr, F, Schuetz, A, Doege, N, Heinemann, U. | 登録日 | 2011-11-11 | 公開日 | 2012-09-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The Lin28 Cold-Shock Domain Remodels Pre-Let-7 Microrna. Nucleic Acids Res., 40, 2012
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6AHX
| Copper-Sensing Operon Regulator Protein (CsoRGz) | 分子名称: | Putative cytosolic protein | 著者 | Normi, M.Y, Mangavelu, A, Sayangku, A.A, Jonet, M.A, Adam, T.C.L, Ali, M.S.M, Rahman, R.N.Z.R.A, Salleh, A.B. | 登録日 | 2018-08-21 | 公開日 | 2019-10-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallization, Structural Determination and Analysis of Copper-sensing Operon Regulator Protein (CsoRGz) of Geobacillus zalihae Strain T1 To Be Published
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6KZI
| Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine derivatives | 分子名称: | 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine, Serine/threonine-protein kinase pim-1 | 著者 | Zhang, W, Wan, X, Li, W, Xie, Y, Huang, N. | 登録日 | 2019-09-24 | 公開日 | 2020-03-04 | 最終更新日 | 2021-03-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. J.Chem.Inf.Model., 60, 2020
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4FV0
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6OD0
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6L15
| Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | 分子名称: | 7-chloranyl-5-[3-[(3~{S})-piperidin-3-yl]propyl]pyrido[3,4-b][1,4]benzoxazine, Serine/threonine-protein kinase pim-1 | 著者 | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | 登録日 | 2019-09-27 | 公開日 | 2020-05-27 | 最終更新日 | 2020-07-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. J.Chem.Inf.Model., 60, 2020
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5JS1
| Human Argonaute2 Bound to an siRNA | 分子名称: | MAGNESIUM ION, PHENOL, Protein argonaute-2, ... | 著者 | Schirle, N.T, MacRae, I.J. | 登録日 | 2016-05-07 | 公開日 | 2016-07-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | 主引用文献 | Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide. J.Am.Chem.Soc., 138, 2016
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5K6E
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4OHT
| Crystal structure of succinic semialdehyde dehydrogenase from Streptococcus pyogenes in complex with NADP+ as the cofactor | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Succinate-semialdehyde dehydrogenase | 著者 | Park, S.A, Jang, E.H, Chi, Y.M, Lee, K.S. | 登録日 | 2014-01-18 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Kinetic and Structural Characterization for Cofactor Preference of Succinic Semialdehyde Dehydrogenase from Streptococcus pyogenes. Mol.Cells, 37, 2014
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7B3D
| Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with AMP at position -4 (structure 3) | 分子名称: | RNA (5'-R(P*CP*UP*AP*CP*GP*CP*AP*GP*UP*G)-3'), RNA (5'-R(P*UP*GP*CP*AP*CP*UP*GP*CP*GP*UP*AP*G)-3'), SARS-CoV-2 RNA-dependent RNA polymerase nsp12, ... | 著者 | Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. | 登録日 | 2020-11-30 | 公開日 | 2020-12-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nat Commun, 12, 2021
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6L12
| Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | 分子名称: | 4-[(2-chloranylphenoxazin-10-yl)methyl]cyclohexan-1-amine, Serine/threonine-protein kinase pim-1 | 著者 | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | 登録日 | 2019-09-27 | 公開日 | 2020-05-27 | 最終更新日 | 2020-07-08 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. J.Chem.Inf.Model., 60, 2020
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4XYI
| Mis16 with H4 peptide | 分子名称: | Histone H4, Kinetochore protein Mis16 | 著者 | An, S, Kim, H, Cho, U.-S. | 登録日 | 2015-02-02 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Mis16 Independently Recognizes Histone H4 and the CENP-ACnp1-Specific Chaperone Scm3sp. J.Mol.Biol., 427, 2015
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7AS4
| Recombinant human gTuRC | 分子名称: | Actin, cytoplasmic 1, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Serna, M, Fernandez-Leiro, R, Llorca, O. | 登録日 | 2020-10-26 | 公開日 | 2021-01-20 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | 主引用文献 | Assembly of the asymmetric human gamma-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase. Sci Adv, 6, 2020
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6OSW
| An order-to-disorder structural switch activates the FoxM1 transcription factor | 分子名称: | Forkhead box M1 | 著者 | Marceau, A.H, Rubin, S.M, Nerli, S, McShane, A.C, Sgourakis, N.G. | 登録日 | 2019-05-02 | 公開日 | 2019-05-29 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | An order-to-disorder structural switch activates the FoxM1 transcription factor. Elife, 8, 2019
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7AXC
| Crystal structure of the hPXR-LBD in complex with ferutinine | 分子名称: | GLYCEROL, ISOPROPYL ALCOHOL, Nuclear receptor subfamily 1 group I member 2, ... | 著者 | Granell, M, Delfosse, V, Bourguet, W. | 登録日 | 2020-11-09 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc.Natl.Acad.Sci.USA, 118, 2021
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7AXJ
| Crystal structure of the hPXR-LBD in complex with estradiol and clotrimazole | 分子名称: | 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, ESTRADIOL, Nuclear receptor subfamily 1 group I member 2 | 著者 | Delfosse, V, Granell, M, Blanc, P, Bourguet, W. | 登録日 | 2020-11-09 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc.Natl.Acad.Sci.USA, 118, 2021
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