7JMD
 
 | Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 1 | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | 著者 | Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | 登録日 | 2020-07-31 | 公開日 | 2020-09-09 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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6CCE
 
 | Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Kanglemycin A | 分子名称: | 1,2-ETHANEDIOL, DNA (57-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | 登録日 | 2018-02-07 | 公開日 | 2018-08-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018
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4QSA
 
 | Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, Carbonic anhydrase 2, ... | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | 登録日 | 2014-07-03 | 公開日 | 2015-01-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | Intrinsic Thermodynamics and Structure Correlation of Benzenesulfonamides with a Pyrimidine Moiety Binding to Carbonic Anhydrases I, II, VII, XII, and XIII Plos One, 9, 2014
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6W18
 
 | Structure of S. pombe Arp2/3 complex in inactive state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1, ... | 著者 | Shaaban, M, Nolen, B.J, Chowdhury, S. | 登録日 | 2020-03-03 | 公開日 | 2020-08-12 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state. Nat.Struct.Mol.Biol., 27, 2020
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6W1U
 
 | RT XFEL structure of Photosystem II 400 microseconds after the second illumination at 2.09 Angstrom resolution | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | 著者 | Ibrahim, M, Fransson, T, Chatterjee, R, Cheah, M.H, Hussein, R, Lassalle, L, Sutherlin, K.D, Young, I.D, Fuller, F.D, Gul, S, Kim, I.-S, Simon, P.S, de Lichtenberg, C, Chernev, P, Bogacz, I, Pham, C, Orville, A.M, Saichek, N, Northen, T.R, Batyuk, A, Carbajo, S, Alonso-Mori, R, Tono, K, Owada, S, Bhowmick, A, Bolotovski, R, Mendez, D, Moriarty, N.W, Holton, J.M, Dobbek, H, Brewster, A.S, Adams, P.D, Sauter, N.K, Bergmann, U, Zouni, A, Messinger, J, Kern, J, Yachandra, V.K, Yano, J. | 登録日 | 2020-03-04 | 公開日 | 2020-05-20 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Untangling the sequence of events during the S2→ S3transition in photosystem II and implications for the water oxidation mechanism. Proc.Natl.Acad.Sci.USA, 117, 2020
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5AMD
 
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6CE1
 
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6CCV
 
 | Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Rifampicin | 分子名称: | 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | 登録日 | 2018-02-07 | 公開日 | 2018-08-15 | 最終更新日 | 2024-12-25 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018
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7JMA
 
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7JFN
 
 | Crystal Structure of Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein from Brucella ovis, closed conformation | 分子名称: | 1,2-ETHANEDIOL, NITRATE ION, POTASSIUM ION, ... | 著者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2020-07-17 | 公開日 | 2020-07-29 | 最終更新日 | 2024-11-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein from Brucella ovis, closed conformation to be published
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4TOB
 
 | 1.95A resolution structure of BfrB (Q151L) from Pseudomonas aeruginosa | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bacterioferritin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lovell, S, Battaile, K.P, Yao, H, Kumar, R, Eshelman, K, Rivera, M. | 登録日 | 2014-06-05 | 公開日 | 2015-02-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Concerted motions networking pores and distant ferroxidase centers enable bacterioferritin function and iron traffic. Biochemistry, 54, 2015
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4TQ0
 
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7JJF
 
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6CFM
 
 | Crystal Structure of the Human vaccinia-related kinase bound to a propynyl-pteridinone inhibitor | 分子名称: | (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7,8-dimethyl-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5H)-one, CHLORIDE ION, GLYCEROL, ... | 著者 | Counago, R.M, dos Reis, C.V, de Souza, G.P, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | 登録日 | 2018-02-15 | 公開日 | 2018-03-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal Structure of the Human vaccinia-related kinase bound to a propynyl-pteridinone inhibitor To Be Published
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7JJU
 
 | Crystal structure of en exoribonuclease-resistant RNA (xrRNA) from Potato leafroll virus (PLRV) | 分子名称: | CACODYLATE ION, Guanidinium, IRIDIUM HEXAMMINE ION, ... | 著者 | Steckelberg, A.-L, Vicens, Q, Auffinger, P, Costantino, D.C, Nix, J.C, Kieft, J.S. | 登録日 | 2020-07-27 | 公開日 | 2020-09-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | 主引用文献 | The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold. Rna, 26, 2020
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7JKC
 
 | Sheep Connexin-46 at 1.9 angstroms resolution by CryoEM | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | 著者 | Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | 登録日 | 2020-07-28 | 公開日 | 2020-09-09 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (1.9 Å) | 主引用文献 | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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7JMX
 
 | Crystal structure of a SARS-CoV-2 cross-neutralizing antibody COVA1-16 Fab | 分子名称: | ACETATE ION, COVA1-16 heavy chain, COVA1-16 light chain, ... | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | 登録日 | 2020-08-03 | 公開日 | 2020-10-14 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity. Immunity, 53, 2020
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7TZC
 
 | A drug and ATP binding site in type 1 ryanodine receptor | 分子名称: | (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Melville, Z, Dridi, H, Yuan, Q, Reiken, S, Anetta, W, Liu, Y, Clarke, O.B, Marks, A.R. | 登録日 | 2022-02-15 | 公開日 | 2022-05-18 | 最終更新日 | 2024-11-13 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | A drug and ATP binding site in type 1 ryanodine receptor. Structure, 30, 2022
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6CHT
 
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4RZF
 
 | Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant | 分子名称: | GLYCEROL, Nuclear receptor subfamily 4 group A member 1 | 著者 | Li, F, Tian, X, Li, A, Li, L, Liu, Y, Chen, H, Wu, Q, Lin, T. | 登録日 | 2014-12-21 | 公開日 | 2015-03-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation. Nat.Chem.Biol., 11, 2015
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6YKL
 
 | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11k | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6YKU
 
 | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11f | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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4KPB
 
 | Crystal structure of cytochrome P450 BM-3 R47E mutant | 分子名称: | Cytochrome P450 BM-3, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sadre-Bazzaz, K, Catalano, J, McDermott, A.E, Tong, L. | 登録日 | 2013-05-13 | 公開日 | 2013-07-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Evidence: A Single Charged Residue Affects Substrate Binding in Cytochrome P450 BM-3. Biochemistry, 52, 2013
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6VVG
 
 | Structure of the Cydia pomonella Granulovirus kinase, PK-1 | 分子名称: | ADENOSINE MONOPHOSPHATE, Arginine kinase | 著者 | Oliver, M.R, Horne, C.R, Keown, J.R, Murphy, J.M, Metcalf, P. | 登録日 | 2020-02-17 | 公開日 | 2021-02-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory alpha C helix. Nat Commun, 12, 2021
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7W1Y
 
 | Human MCM double hexamer bound to natural DNA duplex (polyAT/polyTA) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (49-MER), ... | 著者 | Li, J, Dong, J, Dang, S, Zhai, Y. | 登録日 | 2021-11-21 | 公開日 | 2023-02-08 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | The human pre-replication complex is an open complex. Cell, 186, 2023
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