6TNN
 
 | | Mini-RNase III (Mini-III) bound to 50S ribosome with precursor 23S rRNA | | 分子名称: | 50S ribosomal protein L10, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Oerum, S, Dendooven, T, Gilet, L, Catala, M, Degut, C, Trinquier, A, Barraud, P, Luisi, B, Condon, C, Tisne, C. | | 登録日 | 2019-12-09 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs.
Mol.Cell, 80, 2020
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5AGJ
 | | Crystal structure of the LeuRS editing domain of Candida albicans in complex with the adduct AN2690-AMP | | 分子名称: | POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE | | 著者 | Zhao, H, Palencia, A, Seiradake, E, Ghaemi, Z, Luthey-Schulten, Z, Cusack, S, Martinis, S.A. | | 登録日 | 2015-02-02 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism.
Acs Chem.Biol., 10, 2015
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7XGF
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1D78
 | | HIGH RESOLUTION REFINEMENT OF THE HEXAGONAL A-DNA OCTAMER D(GTGTACAC) AT 1.4 ANGSTROMS RESOLUTION | | 分子名称: | DNA (5'-D(*GP*TP*GP*TP*AP*CP*AP*C)-3') | | 著者 | Thota, N, Li, X.H, Bingman, C.A, Sundaralingam, M. | | 登録日 | 1992-06-12 | | 公開日 | 1993-04-15 | | 最終更新日 | 2023-03-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | High-resolution refinement of the hexagonal A-DNA octamer d(GTGTACAC) at 1.4 A.
Acta Crystallogr.,Sect.D, 49, 1993
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5SNU
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8RF0
 | | WT-CGS sample in nanodisc | | 分子名称: | Cyclic beta-(1,2)-glucan synthase NdvB, URIDINE-5'-DIPHOSPHATE-GLUCOSE, beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose, ... | | 著者 | Sedzicki, J, Ni, D, Lehmann, F, Stahlberg, H, Dehio, C. | | 登録日 | 2023-12-12 | | 公開日 | 2024-03-20 | | 最終更新日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure-function analysis of the cyclic beta-1,2-glucan synthase from Agrobacterium tumefaciens.
Nat Commun, 15, 2024
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8YZD
 | | Structure of JN.1 RBD protein in complex with ACE2. | | 分子名称: | Angiotensin-converting enzyme 2, Spike glycoprotein,Fibritin,fusion protein | | 著者 | Wang, Y.J, Zhang, X, Sun, L. | | 登録日 | 2024-04-06 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-07-23 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3.
Nat Commun, 15, 2024
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2APR
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8YZE
 | | The JN.1 spike protein (S) in complex with ACE2. | | 分子名称: | Angiotensin-converting enzyme 2, Spike glycoprotein,Fibritin,Expression Tag | | 著者 | Wang, Y.J, Zhang, X, Sun, L. | | 登録日 | 2024-04-06 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-07-23 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3.
Nat Commun, 15, 2024
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8GLP
 | | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) | | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. | | 登録日 | 2023-03-22 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (1.67 Å) | | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
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6ZTQ
 | | Cryo-EM structure of respiratory complex I from Mus musculus inhibited by piericidin A at 3.0 A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Bridges, H.R, Blaza, J.N, Agip, A.N.A, Hirst, J. | | 登録日 | 2020-07-20 | | 公開日 | 2020-10-21 | | 最終更新日 | 2025-04-09 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of inhibitor-bound mammalian complex I.
Nat Commun, 11, 2020
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1KIZ
 | | D100E trichodiene synthase complexed with pyrophosphate | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | | 著者 | Rynkiewicz, M.J, Cane, D.E, Christianson, D.W. | | 登録日 | 2001-12-03 | | 公開日 | 2002-03-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | X-ray crystal structures of D100E trichodiene synthase and its pyrophosphate complex reveal the basis for terpene product diversity.
Biochemistry, 41, 2002
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4A8I
 | | Protein crystallization and microgravity: glucose isomerase crystals grown during the PCDF-PROTEIN mission | | 分子名称: | 1,2-ETHANEDIOL, COBALT (II) ION, XYLOSE ISOMERASE | | 著者 | Decanniere, K, Patino-Lopez, L.-D, Sleutel, M, Evrard, C, Van De Weerdt, C, Haumont, E, Gavira, J.A, Otalora, F, Maes, D. | | 登録日 | 2011-11-21 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Protein Crystallization and Microgravity: Glucose Isomerase Crystals Grown During the Pcdf-Protein Mission
To be Published
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4HCF
 | | Crystal Structure of Uncharacterized Cupredoxin-like Domain Protein Cupredoxin_1 with Copper Bound from Bacillus anthracis | | 分子名称: | COPPER (II) ION, Cupredoxin 1, SULFATE ION | | 著者 | Kim, Y, Maltseva, N, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-09-29 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.703 Å) | | 主引用文献 | Crystal Structure of Uncharacterized Cupredoxin-like Domain Protein Cupredoxin_1 with Copper Bound from Bacillus anthracis
To be Published
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4H6C
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8Z6Q
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1FO3
 | | CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH KIFUNENSINE | | 分子名称: | ALPHA1,2-MANNOSIDASE, CALCIUM ION, KIFUNENSINE, ... | | 著者 | Vallee, F, Karaveg, K, Moremen, K.W, Herscovics, A, Howell, P.L. | | 登録日 | 2000-08-24 | | 公開日 | 2001-01-17 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
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7XUR
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3JWQ
 | | Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafil | | 分子名称: | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, MAGNESIUM ION, ZINC ION, ... | | 著者 | Barren, B, Gakhar, L, Muradov, H, Boyd, K.K, Ramaswamy, S, Artemyev, N.O. | | 登録日 | 2009-09-18 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit
Embo J., 28, 2009
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7G9T
 | | PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z18618496 | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, Serine protease NS3, ... | | 著者 | Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. | | 登録日 | 2023-07-03 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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5AAE
 | | Aurora A kinase bound to an imidazopyridine inhibitor (14d) | | 分子名称: | 3-((4-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)-1H-pyrazol-1-yl)methyl)-5-methylisoxazole, AURORA KINASE A | | 著者 | McIntyre, P.J, Bayliss, R. | | 登録日 | 2015-07-24 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | 7-(Pyrazol-4-Yl)-3H-Imidazo[4,5-B]Pyridine-Based Derivatives for Kinase Inhibition: Co-Crystallisation Studies with Aurora-A Reveal Distinct Differences in the Orientation of the Pyrazole N1-Substituent.
Bioorg.Med.Chem.Lett., 25, 2015
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7G9Y
 | | PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z2678251369 | | 分子名称: | 1,2-ETHANEDIOL, 2-tert-butyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. | | 登録日 | 2023-07-03 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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8CF5
 | | Translocation intermediate 1 (TI-1) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | | 登録日 | 2023-02-02 | | 公開日 | 2023-09-20 | | 最終更新日 | 2025-10-01 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
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1RPC
 | | SOLUTION STRUCTURE OF RP 71955, A NEW 21 AMINO ACID TRICYCLIC PEPTIDE ACTIVE AGAINST HIV-1 VIRUS | | 分子名称: | Tricyclic peptide RP 71955 | | 著者 | Frechet, D, Guitton, J.D, Herman, F, Faucher, D, Helynck, G, Monegier Du Sorbier, B, Ridoux, J.P, James-Surcouf, E, Vuilhorgne, M. | | 登録日 | 1993-08-31 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-11-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of RP 71955, a new 21 amino acid tricyclic peptide active against HIV-1 virus.
Biochemistry, 33, 1994
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5WG1
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