2I0L
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![BU of 2i0l by Molmil](/molmil-images/mine/2i0l) | X-ray crystal structure of Sap97 PDZ2 bound to the C-terminal peptide of HPV18 E6. | 分子名称: | Disks large homolog 1, peptide E6 | 著者 | Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M. | 登録日 | 2006-08-10 | 公開日 | 2007-02-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein. J.Virol., 81, 2007
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7A9Q
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![BU of 7a9q by Molmil](/molmil-images/mine/7a9q) | Racemic compound of RNA duplexes. | 分子名称: | RNA (5'-R(*(0C)P*(0C)P*(0G)P*(0C)P*(0C)P*(0U)P*(0G)P*(0G))-3'), RNA (5'-R(*(0C)P*(0U)P*(0G)P*(0G)P*(0G)P*(0C)P*(0G)P*(0G))-3'), RNA (5'-R(*CP*CP*GP*CP*CP*UP*GP*G)-3'), ... | 著者 | Rypniewski, W. | 登録日 | 2020-09-02 | 公開日 | 2021-05-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.185 Å) | 主引用文献 | Broken symmetry between RNA enantiomers in a crystal lattice. Nucleic Acids Res., 49, 2021
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6ZPF
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![BU of 6zpf by Molmil](/molmil-images/mine/6zpf) | Racemic compound of RNA duplexes. | 分子名称: | RNA (5'-R(*(0C)P*(0C)P*(0G)P*(0C)P*(0C)P*(0U)P*(0G)P*(0G))-3'), RNA (5'-R(*(0C)P*(0U)P*(0G)P*(0G)P*(0G)P*(0C)P*(0G)P*(0G))-3'), RNA (5'-R(*CP*CP*GP*CP*CP*UP*GP*G)-3'), ... | 著者 | Rypniewski, W. | 登録日 | 2020-07-08 | 公開日 | 2021-05-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.442 Å) | 主引用文献 | Broken symmetry between RNA enantiomers in a crystal lattice. Nucleic Acids Res., 49, 2021
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6S6U
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6ZRL
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![BU of 6zrl by Molmil](/molmil-images/mine/6zrl) | Racemic compound of RNA duplexes. | 分子名称: | RNA (5'-R(*(0C)P*(0C)P*(0G)P*(0C)P*(0C)P*(0U)P*(0G)P*(0G))-3'), RNA (5'-R(*(0C)P*(0U)P*(0G)P*(0G)P*(0G)P*(0C)P*(0G)P*(0G))-3'), RNA (5'-R(*CP*CP*GP*CP*CP*UP*GP*G)-3'), ... | 著者 | Rypniewski, W. | 登録日 | 2020-07-13 | 公開日 | 2021-05-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Broken symmetry between RNA enantiomers in a crystal lattice. Nucleic Acids Res., 49, 2021
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6ZY5
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![BU of 6zy5 by Molmil](/molmil-images/mine/6zy5) | Cryo-EM structure of the Human topoisomerase II alpha DNA-binding/cleavage domain in State 1 | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2020-07-30 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
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2BTJ
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5XJV
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![BU of 5xjv by Molmil](/molmil-images/mine/5xjv) | Two intermediate states of conformation switch in dual specificity phosphatase 13a | 分子名称: | Dual specificity protein phosphatase 13 isoform A, PHOSPHATE ION | 著者 | Wei, C.H, Min, H.G, Chun, H.J, Ryu, S.E. | 登録日 | 2017-05-04 | 公開日 | 2018-04-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Two intermediate states of the conformational switch in dual specificity phosphatase 13a Pharmacol. Res., 128, 2018
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6ZWI
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![BU of 6zwi by Molmil](/molmil-images/mine/6zwi) | Human butyrylcholinesterase in complex with ((6-((2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienamido)hexyl)triphenylphosphonium bromide) | 分子名称: | (2~{E},4~{E})-5-(1,3-benzodioxol-5-yl)-~{N}-[6-(triphenyl-$l^{5}-phosphanyl)hexyl]penta-2,4-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Da Silva, O, Nachon, F, Dias, J, Brazzolotto, X. | 登録日 | 2020-07-28 | 公開日 | 2021-06-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases. Antioxidants (Basel), 10, 2021
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4ZCD
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![BU of 4zcd by Molmil](/molmil-images/mine/4zcd) | Renalase in complex with NAD+ | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Silvaggi, N.R, Moran, G.R, Roman, J.V. | 登録日 | 2015-04-15 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.6605 Å) | 主引用文献 | Bacterial Renalase: Structure and Kinetics of an Enzyme with 2- and 6-Dihydro-beta-NAD(P) Oxidase Activity from Pseudomonas phaseolicola. Biochemistry, 54, 2015
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6RK2
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![BU of 6rk2 by Molmil](/molmil-images/mine/6rk2) | Complex structure of virulence factor SghA mutant with its substrate SAG | 分子名称: | 2-(alpha-L-altropyranosyloxy)benzoic acid, Beta-glucosidase | 著者 | Ye, F.Z, Wang, C, Chang, C.Q, Zhang, L.H, Gao, Y.G. | 登録日 | 2019-04-30 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Agrobacteria reprogram virulence gene expression by controlled release of host-conjugated signals. Proc.Natl.Acad.Sci.USA, 116, 2019
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6RKG
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![BU of 6rkg by Molmil](/molmil-images/mine/6rkg) | 1.32 A RESOLUTION OF SPOROSARCINA PASTEURII UREASE INHIBITED IN THE PRESENCE OF NBPTO AT pH 7.5 | 分子名称: | 1,2-ETHANEDIOL, DIAMIDOPHOSPHATE, NICKEL (II) ION, ... | 著者 | Mazzei, L, Cianci, M, Benini, S, Ciurli, S. | 登録日 | 2019-04-30 | 公開日 | 2020-03-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | The Impact of pH on Catalytically Critical Protein Conformational Changes: The Case of the Urease, a Nickel Enzyme. Chemistry, 25, 2019
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6RKW
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![BU of 6rkw by Molmil](/molmil-images/mine/6rkw) | CryoEM structure of the complete E. coli DNA Gyrase complex bound to a 130 bp DNA duplex | 分子名称: | (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA (58-MER), DNA (62-MER), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2019-04-30 | 公開日 | 2019-11-06 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nat Commun, 10, 2019
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6S7F
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4ZFA
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![BU of 4zfa by Molmil](/molmil-images/mine/4zfa) | Cytochrome P450 wild type from BM3 with bound PEG | 分子名称: | 1,2-ETHANEDIOL, Bifunctional P-450/NADPH-P450 reductase, NICKEL (II) ION, ... | 著者 | Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. | 登録日 | 2015-04-21 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.765 Å) | 主引用文献 | Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
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4ZGX
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![BU of 4zgx by Molmil](/molmil-images/mine/4zgx) | Structure of aldosterone synthase (CYP11B2) in complex with (+)-(R)-N-(4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide | 分子名称: | Cytochrome P450 11B2, mitochondrial, N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide, ... | 著者 | Kuglstatter, A, Joseph, C. | 登録日 | 2015-04-24 | 公開日 | 2015-10-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys. J.Med.Chem., 58, 2015
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2L9B
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![BU of 2l9b by Molmil](/molmil-images/mine/2l9b) | Heterodimer between Rna14p monkeytail domain and Rna15p hinge domain of the yeast CF IA complex | 分子名称: | mRNA 3'-end-processing protein RNA14, mRNA 3'-end-processing protein RNA15 | 著者 | Moreno-Morcillo, M, Minvielle-Sebastia, L, Fribourg, S, Mackereth, C.D. | 登録日 | 2011-02-07 | 公開日 | 2011-04-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Locked Tether Formation by Cooperative Folding of Rna14p Monkeytail and Rna15p Hinge Domains in the Yeast CF IA Complex. Structure, 19, 2011
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4ZIX
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![BU of 4zix by Molmil](/molmil-images/mine/4zix) | Structure of HEWL using Serial Femtosecond Crystallography of Soluble Proteins in Lipidic Cubic Phase | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Fromme, R, Ishchenko, A, Metz, M, Roy-Chowdhury, S, Basu, S, Boutet, S, Fromme, P, White, T.A, Barty, A, Spence, J.C.H, Weierstall, U, Liu, W, Cherezov, V. | 登録日 | 2015-04-28 | 公開日 | 2015-08-12 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Serial Femtosecond Crystallography of Soluble Proteins in Lipidic Cubic Phase IUCrJ, 2, 2015
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6RHQ
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![BU of 6rhq by Molmil](/molmil-images/mine/6rhq) | Crystal Structure of Two-Domain Laccase mutant I170A from Streptomyces griseoflavus | 分子名称: | COPPER (II) ION, GLYCEROL, SULFATE ION, ... | 著者 | Gabdulkhakov, A.G, Tishchenko, T.V, Kolyadenko, I.A. | 登録日 | 2019-04-22 | 公開日 | 2019-07-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Investigations of Accessibility of T2/T3 Copper Center of Two-Domain Laccase fromStreptomyces griseoflavusAc-993. Int J Mol Sci, 20, 2019
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5XMG
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4ZO6
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![BU of 4zo6 by Molmil](/molmil-images/mine/4zo6) | Crystal Structure of mutant (D270A) beta-glucosidase from Listeria innocua in complex with cellobiose | 分子名称: | GLYCEROL, Lin1840 protein, MAGNESIUM ION, ... | 著者 | Nakajima, M, Yoshida, R, Miyanaga, A, Abe, K, Takahashi, Y, Sugimoto, N, Toyoizumi, H, Nakai, H, Kitaoka, M, Taguchi, H. | 登録日 | 2015-05-06 | 公開日 | 2016-05-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Functional and Structural Analysis of a beta-Glucosidase Involved in beta-1,2-Glucan Metabolism in Listeria innocua Plos One, 11, 2016
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6RTT
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![BU of 6rtt by Molmil](/molmil-images/mine/6rtt) | Piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus complexed with picolinic acid | 分子名称: | GLYCEROL, PYRIDINE-2-CARBOXYLIC ACID, SULFATE ION, ... | 著者 | Hasse, D, Huelsemann, J, Carlsson, G, Andersson, I. | 登録日 | 2019-05-26 | 公開日 | 2019-12-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure and mechanism of piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus. Acta Crystallogr D Struct Biol, 75, 2019
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2BXF
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![BU of 2bxf by Molmil](/molmil-images/mine/2bxf) | Human serum albumin complexed with diazepam | 分子名称: | 7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE, SERUM ALBUMIN | 著者 | Ghuman, J, Zunszain, P.A, Petitpas, I, Bhattacharya, A.A, Curry, S. | 登録日 | 2005-07-26 | 公開日 | 2005-09-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural Basis of the Drug-Binding Specificity of Human Serum Albumin. J.Mol.Biol., 353, 2005
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6RUA
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![BU of 6rua by Molmil](/molmil-images/mine/6rua) | Structure of recombinant human butyrylcholinesterase in complex with a coumarin-based fluorescent probe linked to sulfonamide type inhibitor. | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Coquelle, N, Knez, D, Brus, B, Gobec, S, Colletier, J.P. | 登録日 | 2019-05-27 | 公開日 | 2020-01-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes. J Enzyme Inhib Med Chem, 35, 2020
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6RKS
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![BU of 6rks by Molmil](/molmil-images/mine/6rks) | E. coli DNA Gyrase - DNA binding and cleavage domain in State 1 without TOPRIM insertion | 分子名称: | (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA Strand 1, DNA Strand 2, ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2019-04-30 | 公開日 | 2019-11-06 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nat Commun, 10, 2019
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