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5Z27
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Crystal structure of highly active BTUO mutant P287G without dehydration
分子名称: 1,2-ETHANEDIOL, 8-AZAXANTHINE, OXYGEN MOLECULE, ...
著者Hibi, T, Itoh, T, Nishiya, Y.
登録日2017-12-29
公開日2019-01-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Flexibility of a Distal Interface Loop Modulates Water Network in the Active Site of Bacillus sp. TB-90 Urate Oxidase
to be published
3OGH
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BU of 3ogh by Molmil
Crystal structure of yciE protein from E. coli CFT073, a member of ferritine-like superfamily of diiron-containing four-helix-bundle proteins
分子名称: CHLORIDE ION, FE (III) ION, MAGNESIUM ION, ...
著者Nocek, B, Bigelow, L, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2010-08-16
公開日2010-09-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of yciE protein from E. coli CFT073, a member of ferritine-like superfamily of diiron-containing four-helix-bundle proteins
To be Published
3OJG
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BU of 3ojg by Molmil
Structure of an inactive lactonase from Geobacillus kaustophilus with bound N-butyryl-DL-homoserine lactone
分子名称: FE (III) ION, N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide, Phosphotriesterase, ...
著者Xue, B, Chow, J.Y, Tung, A, Robinson, R.C.
登録日2010-08-22
公開日2010-10-27
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily
J.Biol.Chem., 285, 2010
3PEB
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BU of 3peb by Molmil
The Structure of a Creatine_N Superfamily domain of a dipeptidase from Streptococcus thermophilus.
分子名称: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Dipeptidase, ...
著者Cuff, M.E, Mack, J.C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2010-10-25
公開日2010-11-03
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献The Structure of a Creatine_N Superfamily domain of a dipeptidase from Streptococcus thermophilus.
TO BE PUBLISHED
4FGT
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Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes inactive conformation of the enzyme.
分子名称: CG peptide, SULFATE ION, Thymidylate synthase
著者Tochowicz, A, Finer-Moore, J, Stroud, R.M, Costi, M.P.
登録日2012-06-04
公開日2013-03-06
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Alanine mutants of the interface residues of human thymidylate synthase decode key features of the binding mode of allosteric anticancer peptides.
J.Med.Chem., 58, 2015
2L66
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BU of 2l66 by Molmil
The DNA-recognition fold of Sso7c4 suggests a new member of SpoVT-AbrB superfamily from archaea.
分子名称: Transcriptional regulator, AbrB family
著者Hsu, C.-H, Wang, A.H.-J.
登録日2010-11-17
公開日2011-09-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The DNA-recognition fold of Sso7c4 suggests a new member of SpoVT-AbrB superfamily from archaea.
Nucleic Acids Res., 39, 2011
4JXR
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BU of 4jxr by Molmil
Crystal structure of a GNAT superfamily phosphinothricin acetyltransferase (Pat) from Sinorhizobium meliloti in complex with AcCoA
分子名称: ACETYL COENZYME *A, Acetyltransferase, CITRATE ANION, ...
著者Majorek, K.A, Cooper, D.R, Porebski, P.J, Konina, K, Ahmed, M, Stead, M, Hillerich, B, Seidel, R, Bonanno, J.B, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2013-03-28
公開日2013-05-15
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal structure of a GNAT superfamily phosphinothricin acetyltransferase (Pat) from Sinorhizobium meliloti in complex with AcCoA
To be Published
4KFC
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BU of 4kfc by Molmil
Crystal structure of a hyperactive mutant of response regulator KdpE complexed to its promoter DNA
分子名称: KDP operon transcriptional regulatory protein KdpE, Promoter DNA
著者Kumar, S, Narayanan, A, Yernool, D.A.
登録日2013-04-26
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献An asymmetric heterodomain interface stabilizes a response regulator-DNA complex.
Nat Commun, 5, 2014
4Z81
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BU of 4z81 by Molmil
Crystal structure of AMA4 DI-DII-EGF1 from Toxoplasma gondii
分子名称: EGF family domain-containing protein, GLYCEROL
著者Parker, M.L, Boulanger, M.J.
登録日2015-04-08
公開日2015-12-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
4K2H
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BU of 4k2h by Molmil
Crystal structure of C103A mutant of DJ-1 superfamily protein STM1931 from Salmonella typhimurium
分子名称: Intracellular protease/amidase, ZINC ION
著者Shumilin, I.A, Niedzialkowska, E, Domagalski, M.J, Stam, J, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-04-09
公開日2013-04-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of C103A mutant of DJ-1 superfamily protein STM1931 from Salmonella typhimurium
TO BE PUBLISHED
4B6P
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BU of 4b6p by Molmil
Structure of Mycobacterium tuberculosis Type II Dehydroquinase inhibited by (2S)-2-Perfluorobenzyl-3-dehydroquinic acid
分子名称: (1R,2S,4S,5R)-2-(2,3,4,5,6-pentafluorophenyl)methyl-1,4,5-trihydroxy-3-oxocyclohexane-1-carboxylic acid, 3-DEHYDROQUINATE DEHYDRATASE, SULFATE ION
著者Otero, J.M, Llamas-Saiz, A.L, Lence, E, Tizon, L, Peon, A, Prazeres, V.F.V, Lamb, H, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J.
登録日2012-08-14
公開日2012-12-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanistic basis of the inhibition of type II dehydroquinase by (2S)- and (2R)-2-benzyl-3-dehydroquinic acids.
ACS Chem. Biol., 8, 2013
4HOR
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BU of 4hor by Molmil
Crystal Structure of Full-Length Human IFIT5 with 5`-triphosphate Oligocytidine
分子名称: Interferon-induced protein with tetratricopeptide repeats 5, MAGNESIUM ION, RNA (5'-R(*(CTP)P*CP*CP*CP*C)-3')
著者Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B.
登録日2012-10-22
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.861 Å)
主引用文献Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
1EZ4
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BU of 1ez4 by Molmil
CRYSTAL STRUCTURE OF NON-ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS PENTOSUS AT 2.3 ANGSTROM RESOLUTION
分子名称: LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Uchikoba, H, Fushinobu, S, Wakagi, T, Konno, M, Taguchi, H, Matsuzawa, H.
登録日2000-05-10
公開日2001-12-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of non-allosteric L-lactate dehydrogenase from Lactobacillus pentosus at 2.3 A resolution: specific interactions at subunit interfaces.
Proteins, 46, 2002
3CG6
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BU of 3cg6 by Molmil
Crystal structure of Gadd45 gamma
分子名称: Growth arrest and DNA-damage-inducible 45 gamma
著者Schrag, J.D, Jiralerspong, S, Banville, M, Jaramillo, M.L, O'Connor-McCourt, M.D.
登録日2008-03-05
公開日2008-04-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure and dimerization interface of GADD45gamma.
Proc.Natl.Acad.Sci.Usa, 105, 2008
4HOT
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BU of 4hot by Molmil
Crystal Structure of Full-Length Human IFIT5 with 5`-triphosphate Oligoadenine
分子名称: Interferon-induced protein with tetratricopeptide repeats 5, MAGNESIUM ION, RNA (5'-R(*(ATP)P*AP*AP*A)-3')
著者Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B.
登録日2012-10-22
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
4I4K
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BU of 4i4k by Molmil
Streptomyces globisporus C-1027 9-membered enediyne conserved protein SgcE6
分子名称: CITRIC ACID, GLYCEROL, PENTAETHYLENE GLYCOL, ...
著者Kim, Y, Bigelow, L, Clancy, S, Babnigg, J, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-11-27
公開日2012-12-12
最終更新日2016-12-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027.
J Antibiot (Tokyo), 69, 2016
4HOQ
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BU of 4hoq by Molmil
Crystal Structure of Full-Length Human IFIT5
分子名称: Interferon-induced protein with tetratricopeptide repeats 5
著者Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B.
登録日2012-10-22
公開日2013-01-23
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
3RON
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BU of 3ron by Molmil
Crystal Structure and Hemolytic Activity of the Cyt1Aa Toxin from Bacillus thuringiensis subsp. israelensis
分子名称: Type-1Aa cytolytic delta-endotoxin
著者Cohen, S, Albeck, S, Ben-Dov, E, Cahan, R, Firer, M, Zaritsky, A, Dym, O, Israel Structural Proteomics Center (ISPC)
登録日2011-04-26
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Cyt1Aa Toxin: Crystal Structure Reveals Implications for Its Membrane-Perforating Function.
J.Mol.Biol., 413, 2011
4HOS
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BU of 4hos by Molmil
Crystal Structure of Full-Length Human IFIT5 with 5`-triphosphate Oligouridine
分子名称: Interferon-induced protein with tetratricopeptide repeats 5, RNA (5'-R(*(UTP)P*UP*UP*U)-3'), SODIUM ION
著者Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B.
登録日2012-10-22
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
2CBJ
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BU of 2cbj by Molmil
Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc
分子名称: CHLORIDE ION, HYALURONIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE
著者Rao, F.V, Dorfmueller, H.C, Villa, F, Allwood, M, Eggleston, I.M, van Aalten, D.M.F.
登録日2006-01-05
公開日2006-02-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis.
EMBO J., 25, 2006
3IE5
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BU of 3ie5 by Molmil
Crystal structure of Hyp-1 protein from Hypericum perforatum (St John's wort) involved in hypericin biosynthesis
分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Michalska, K, Fernandes, H, Sikorski, M.M, Jaskolski, M.
登録日2009-07-22
公開日2009-11-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.688 Å)
主引用文献Crystal structure of Hyp-1, a St. John's wort protein implicated in the biosynthesis of hypericin
J.Struct.Biol., 169, 2010
4QXG
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BU of 4qxg by Molmil
Antigen binding fragment of an anti IFNAR1 antibody
分子名称: Fab, heavy chain, IgG1, ...
著者Oganesyan, V.Y, Dall'Acqua, W.F.
登録日2014-07-20
公開日2015-02-25
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis for antagonistic activity of anifrolumab, an anti-interferon-alpha receptor 1 antibody.
MAbs, 7, 2015
4Z80
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BU of 4z80 by Molmil
Crystal structure of Toxoplasma gondii AMA4 DI-DII-EGF1 in complex with a 33 aa TgRON2L1 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytoadherence-linked asexual protein, EGF family domain-containing protein, ...
著者Parker, M.L, Boulanger, M.J.
登録日2015-04-08
公開日2015-12-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
2CBI
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BU of 2cbi by Molmil
Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase
分子名称: CHLORIDE ION, GAMMA-BUTYROLACTONE, GLYCEROL, ...
著者Rao, F.V, Dorfmueller, H.C, Villa, F, Allwood, M, Eggleston, I.M, van Aalten, D.M.F.
登録日2006-01-04
公開日2006-02-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis.
EMBO J., 25, 2006
3ZK7
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BU of 3zk7 by Molmil
CRYSTAL STRUCTURE OF PNEUMOCOCCAL SURFACE ANTIGEN PSAA IN THE METAL-FREE, OPEN STATE
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN
著者Counago, R.M, Ween, M.P, Bajaj, M, Zuegg, J, Cooper, M.A, McEwan, A.G, Paton, J.C, Kobe, B, McDevitt, C.A.
登録日2013-01-22
公開日2013-11-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Imperfect coordination chemistry facilitates metal ion release in the Psa permease.
Nat. Chem. Biol., 10, 2014

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