8RGE
| Serial synchrotron in plate room temperature structure of Lysozyme. | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Thompson, A.J, Hough, M.A, Sanchez-Weatherby, J, Williams, L.J, Sandy, J, Worrall, J.A.R. | 登録日 | 2023-12-13 | 公開日 | 2023-12-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Efficient in situ screening of and data collection from microcrystals in crystallization plates. Acta Crystallogr D Struct Biol, 80, 2024
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7AC4
| Structure of insulin collected by rotation serial crystallography on a COC membrane at a synchrotron source | 分子名称: | Insulin, R-1,2-PROPANEDIOL, SODIUM ION | 著者 | Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M. | 登録日 | 2020-09-09 | 公開日 | 2021-09-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Versatile microporous polymer-based supports for serial macromolecular crystallography. Acta Crystallogr D Struct Biol, 77, 2021
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7AC2
| Structure of Hen Egg White Lysozyme collected by rotation serial crystallography on a COC membrane at a synchrotron source | 分子名称: | CHLORIDE ION, Lysozyme, SODIUM ION | 著者 | Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M. | 登録日 | 2020-09-09 | 公開日 | 2021-09-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.507 Å) | 主引用文献 | Versatile microporous polymer-based supports for serial macromolecular crystallography. Acta Crystallogr D Struct Biol, 77, 2021
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8AFD
| CRYSTAL STRUCTURE OF BIT-BLOCKED KRAS-G12V-S39C IN COMPLEX WITH COMPOUND 20a | 分子名称: | (4~{S})-4-[3-(4-aminophenyl)-1,2,4-oxadiazol-5-yl]-2-azanyl-4-methyl-6,7-dihydro-5~{H}-1-benzothiophene-3-carbonitrile, 1H-benzimidazol-2-ylmethanethiol, GTPase KRas, ... | 著者 | Boettcher, J, Kessler, D. | 登録日 | 2022-07-16 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.633 Å) | 主引用文献 | Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS G12C Inhibitor. J.Med.Chem., 65, 2022
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5G5J
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7A9K
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7A9F
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8AJ4
| X-ray structure of lysozyme obtained upon reaction with [VIVO(malt)2] (Structure A') | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8,8-bis($l^{1}-oxidanyl)-2,2'-dimethyl-8,8'-spirobi[3$l^{4},7,9-trioxa-8$l^{6}-vanadabicyclo[4.3.0]nona-1(6),2,4-triene], Lysozyme, ... | 著者 | Paolillo, M, Merlino, A, Ferraro, G. | 登録日 | 2022-07-27 | 公開日 | 2022-11-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Multiple and Variable Binding of Pharmacologically Active Bis(maltolato)oxidovanadium(IV) to Lysozyme. Inorg.Chem., 61, 2022
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5GIB
| Succinic acid bound trypsin crystallized as dimer | 分子名称: | CALCIUM ION, Cationic trypsin, SUCCINIC ACID | 著者 | Kutumbarao, N.H.V, Manohar, R, KarthiK, L, Malathy, P, Gunasekaran, K, Velmurugan, D. | 登録日 | 2016-06-22 | 公開日 | 2016-08-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.697 Å) | 主引用文献 | Trypsin bound with Succinic acid To Be Published
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6U81
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7ADF
| SFX structure of dehaloperoxidase B in the ferric form | 分子名称: | Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Moreno Chicano, T, Ebrahim, A.E, Axford, D.A, Sherrell, D.A, Sugimoto, H, Tono, K, Owada, S, Worrall, J.W, Strange, R.W, Owen, R.L, Hough, M.A. | 登録日 | 2020-09-14 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | SFX structure of dehaloperoxidase B in the ferric form to be published
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8AJ3
| X-ray structure of lysozyme obtained upon reaction with [VIVO(malt)2] (Structure A) | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8,8,8,8-tetrakis($l^{1}-oxidanyl)-2-methyl-3,7,9-trioxa-8$l^{6}-vanadabicyclo[4.3.0]nona-1,5-diene, 8,8-bis($l^{1}-oxidanyl)-2,2'-dimethyl-8,8'-spirobi[3$l^{4},7,9-trioxa-8$l^{6}-vanadabicyclo[4.3.0]nona-1(6),2,4-triene], ... | 著者 | Paolillo, M, Merlino, A, Ferraro, G. | 登録日 | 2022-07-27 | 公開日 | 2022-11-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Multiple and Variable Binding of Pharmacologically Active Bis(maltolato)oxidovanadium(IV) to Lysozyme. Inorg.Chem., 61, 2022
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8AJ5
| X-ray structure of lysozyme obtained upon reaction with [VIVO(malt)2] (Structure B) | 分子名称: | ACETATE ION, Lysozyme, NITRATE ION, ... | 著者 | Paolillo, M, Merlino, A, Ferraro, G. | 登録日 | 2022-07-27 | 公開日 | 2022-11-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Multiple and Variable Binding of Pharmacologically Active Bis(maltolato)oxidovanadium(IV) to Lysozyme. Inorg.Chem., 61, 2022
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4QYH
| CHK1 kinase domain in complex with diazacarbazole GNE-783 | 分子名称: | 3-[4-(4-methylpiperazin-1-yl)phenyl]-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile, Serine/threonine-protein kinase Chk1 | 著者 | Wiesmann, C, Wu, P. | 登録日 | 2014-07-24 | 公開日 | 2014-12-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1. Bioorg.Med.Chem.Lett., 24, 2014
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6I7U
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5GKB
| Crystal Structure of Fatty Acid-Binding Protein in Brain Tissue of Drosophila melanogaster without citrate inside | 分子名称: | Fatty acid bindin protein, isoform B | 著者 | Cheng, Y.-Y, Huang, Y.-F, Lin, H.-H, Chang, W.W, Lyu, P.-C. | 登録日 | 2016-07-04 | 公開日 | 2017-07-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | The ligand-mediated affinity of brain-type fatty acid-binding protein for membranes determines the directionality of lipophilic cargo transport. Biochim Biophys Acta Mol Cell Biol Lipids, 1864, 2019
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7ADG
| Cocktail experiment G: fragments 216 and 338 at 90 mM concentration in complex with Endothiapepsin | 分子名称: | 2-(1H-imidazol-1-yl)-N-(trans-4-methylcyclohexyl)acetamide, ACETATE ION, DIMETHYL SULFOXIDE, ... | 著者 | Hassaan, E, Klebe, G, Heine, A, Schiebel, J, Koester, H. | 登録日 | 2020-09-14 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.0794636 Å) | 主引用文献 | Comparison of Cocktail Screening in X-Ray Crystallography vs NMR To Be Published
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4RCD
| Crystal structure of BACE1 in complex with a 2-aminooxazoline 4-azaxanthene inhibitor | 分子名称: | (5S)-7-(2-fluoropyridin-3-yl)-3-[(3-methyloxetan-3-yl)ethynyl]spiro[chromeno[2,3-b]pyridine-5,4'-[1,3]oxazol]-2'-amine, Beta-secretase 1, GLYCEROL, ... | 著者 | Whittington, D.A, Long, A.M. | 登録日 | 2014-09-15 | 公開日 | 2015-01-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Inhibitors of beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1): Identification of (S)-7-(2-Fluoropyridin-3-yl)-3-((3-methyloxetan-3-yl)ethynyl)-5'H-spiro[chromeno[2,3-b]pyridine-5,4'-oxazol]-2'-amine (AMG-8718). J.Med.Chem., 57, 2014
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7A9M
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8B02
| Crystal structure of the dsRBD domain of tRNA-dihydrouridine(20) synthase from Amphimedon queenslandica | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, DRBM domain-containing protein, ... | 著者 | Pecqueur, L, Faivre, B, Hamdane, D. | 登録日 | 2022-09-07 | 公開日 | 2022-11-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.676 Å) | 主引用文献 | Evolutionary Diversity of Dus2 Enzymes Reveals Novel Structural and Functional Features among Members of the RNA Dihydrouridine Synthases Family. Biomolecules, 12, 2022
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4RDS
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7ACP
| Serial synchrotron structure of dehaloperoxidase B | 分子名称: | Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Moreno Chicano, T, Ebrahim, A.E, Axford, D.A, Sherrell, D.A, Worrall, J.W, Strange, R.W, Owen, R.L, Hough, M.A. | 登録日 | 2020-09-11 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | SFX structure of dehaloperoxidase B in the ferric form to be published
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7ADQ
| Serial Laue crystallography structure of dehaloperoxidase B from Amphitrite ornata | 分子名称: | Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Moreno-Chicano, T.M, Ebrahim, A.E, Srajer, V, Henning, R.W, Doak, B.C, Trebbin, M, Monteiro, D.C.F, Hough, M.A. | 登録日 | 2020-09-15 | 公開日 | 2021-11-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature. Iucrj, 9, 2022
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7ADX
| SFX structure of dehaloperoxidase B in the oxyferrous form | 分子名称: | Dehaloperoxidase B, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Moreno Chicano, T, Ebrahim, A, Worrall, J.W, Axford, D.A, Owada, S, Tosha, T, Sugimoto, H, Strange, R.W, Owen, R.L, Hough, M.A. | 登録日 | 2020-09-16 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | SFX structure of dehaloperoxidase B from Amphitrite ornata in the oxyferrous form To Be Published
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7A1X
| KRASG12C GDP form in complex with Cpd1 | 分子名称: | 3-(imidazol-1-ylmethyl)-1~{H}-indole, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Mathieu, M, Steier, V. | 登録日 | 2020-08-14 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | KRAS G12C fragment screening renders new binding pockets. Small Gtpases, 13, 2022
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