PDB: 35756 件ウェブページステータス検索Chemie searchBIRD

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7XUG	cryo-EM structure of HK022 putRNA-less E.coli RNA polymerase elongation complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Hwang, S, Kang, J.Y. 登録日 2022-05-18 公開日 2022-08-10 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA. Nat Commun, 13, 2022
7XUI	Cryo-EM structure of sigma70 bound HK022 putRNA-associated E.coli RNA polymerase elongation complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Hwang, S, Kang, J.Y. 登録日 2022-05-18 公開日 2022-08-10 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.61 Å) 主引用文献 Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA. Nat Commun, 13, 2022
217D	CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN 分子名称: DISTAMYCIN A, DNA/RNA (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3'), MAGNESIUM ION 著者 Chen, X, Ramakrishnan, B, Sundaralingam, M. 登録日 1995-07-18 公開日 1996-01-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of B-form DNA-RNA chimers complexed with distamycin. Nat.Struct.Biol., 2, 1995
1L45	CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY 分子名称: T4 LYSOZYME 著者 Daopin, S, Matthews, B.W. 登録日 1991-01-28 公開日 1991-10-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability. J.Mol.Biol., 221, 1991
1GFG	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-12-04 公開日 2000-12-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability. J.Biol.Chem., 277, 2002
1GFR	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-12-04 公開日 2000-12-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability. J.Biol.Chem., 277, 2002
1L55	ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Nicholson, H, Matthews, B.W. 登録日 1991-05-06 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991
1LGV	Structure of a Human Bence-Jones Dimer Crystallized in U.S. Space Shuttle Mission STS-95: 100K 分子名称: IMMUNOGLOBULIN LAMBDA LIGHT CHAIN 著者 Terzyan, S.S, DeWitt, C.R, Ramsland, P.A, Bourne, P.C, Edmundson, A.B. 登録日 2002-04-16 公開日 2003-07-01 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Comparison of the three-dimensional structures of a human Bence-Jones dimer crystallized on Earth and aboard US Space Shuttle Mission STS-95 J.MOL.RECOG., 16, 2003
5CLE	Alkylpurine DNA glycosylase AlkD bound to DNA containing an abasic-site analog and a free 3-methyladenine nucleobase 分子名称: 3-METHYL-3H-PURIN-6-YLAMINE, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(3DR)P*AP*GP*TP*CP*CP*G)-3'), ... 著者 Mullins, E.A, Eichman, B.F. 登録日 2015-07-16 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions. Nature, 527, 2015
4PTG	Structure of a carboxamine compound (26) (2-{2-[(CYCLOPROPYLCARBONYL)AMINO]PYRIDIN-4-YL}-4-METHOXYPYRIMIDINE-5-CARBOXAMIDE) to GSK3b 分子名称: 2-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}-4-methoxypyrimidine-5-carboxamide, Glycogen synthase kinase-3 beta 著者 Lewis, H.A, Sivaprakasam, P, Kish, K, Pokross, M, Dubowchik, G.M. 登録日 2014-03-10 公開日 2015-04-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.361 Å) 主引用文献 Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorg.Med.Chem.Lett., 25, 2015
5CLV	Crystal Structure of KorA-operator DNA complex (KorA-OA) 分子名称: 5'-D(CP*CP*AP*AP*GP*TP*TP*TP*AP*GP*CP*TP*AP*AP*AP*CP*TP*TP*GP*GP*)-3', TrfB transcriptional repressor protein 著者 White, S.A, Hyde, E.I, Rajasekar, K.V. 登録日 2015-07-16 公開日 2016-04-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator. Nucleic Acids Res., 44, 2016
6KHD	Crystal structure of CLK1 in complex with CX-4945 分子名称: 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Dual specificity protein kinase CLK1 著者 Lee, J.Y, Yun, J.S, Jin, H, Chang, J.H. 登録日 2019-07-15 公開日 2019-10-02 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Basis for the Selective Inhibition of Cdc2-Like Kinases by CX-4945. Biomed Res Int, 2019, 2019
2CBL	N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE ON ZAP-70 分子名称: CALCIUM ION, PROTO-ONCOGENE CBL, ZAP-70 著者 Meng, W, Sawasdikosol, S, Burakoff, S.J, Eck, M.J. 登録日 1998-08-28 公開日 1999-05-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase. Nature, 398, 1999
1L69	MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Zhang, X, Matthews, B.W. 登録日 1991-09-23 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992
1GN9	Hybrid Cluster Protein from Desulfovibrio desulfuricans ATCC 27774 X-ray structure at 2.6A resolution using synchrotron radiation at a wavelength of 1.722A 分子名称: HYBRID CLUSTER PROTEIN, IRON/SULFUR CLUSTER, IRON/SULFUR/OXYGEN HYBRID CLUSTER 著者 Macedo, S, Mitchell, E.P, Romao, C.V, Cooper, S.J, Coelho, R, Liu, M.Y, Xavier, A.V, Legall, J, Bailey, S, Garner, D.C, Hagen, W.R, Teixeira, M, Carrondo, M.A, Lindley, P. 登録日 2001-10-04 公開日 2002-04-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Hybrid Cluster Proteins (Hcps) from Desulfovibrio Desulfuricans Atcc 27774 and Desulfovibrio Vulgaris (Hildenborough): X-Ray Structures at 1.25 A Resolution Using Synchrotron Radiation. J.Biol.Inorg.Chem., 7, 2002
5CL3	Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog (100% substrate at 4 hours) 分子名称: AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*AP*CP*TP*TP*TP*CP*GP*GP*G)-3') 著者 Mullins, E.A, Eichman, B.F. 登録日 2015-07-16 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.971 Å) 主引用文献 The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions. Nature, 527, 2015
5CL8	Alkylpurine DNA glycosylase AlkD bound to DNA containing an abasic site and a free nucleobase (100% product at 144 hours) 分子名称: 7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(ORP)P*AP*GP*TP*CP*CP*G)-3'), ... 著者 Mullins, E.A, Eichman, B.F. 登録日 2015-07-16 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions. Nature, 527, 2015
2C7I	Structure of protein Ta0514, putative lipoate protein ligase from T. acidophilum. 分子名称: PUTATIVE LIPOATE PROTEIN LIGASE 著者 Mcmanus, E, Perham, R.N, Luisi, B.F. 登録日 2005-11-24 公開日 2005-12-15 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of a Putative Lipoate Protein Ligase from Thermoplasma Acidophilum and the Mechanism of Target Selection for Post-Translational Modification. J.Mol.Biol., 356, 2006
1ZUI	Structural Basis for Shikimate-binding Specificity of Helicobacter pylori Shikimate Kinase 分子名称: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, PHOSPHATE ION, Shikimate kinase 著者 Cheng, W.C, Chang, Y.N, Wang, W.C. 登録日 2005-05-31 公開日 2006-05-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for shikimate-binding specificity of Helicobacter pylori shikimate kinase J.Bacteriol., 187, 2005
2CLQ	Structure of mitogen-activated protein kinase kinase kinase 5 分子名称: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5, STAUROSPORINE 著者 Bunkoczi, G, Salah, E, Fedorov, O, Pike, A, Gileadi, O, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Knapp, S. 登録日 2006-04-28 公開日 2006-05-09 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and Functional Characterization of the Human Protein Kinase Ask1. Structure, 15, 2007
1L85	SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME 著者 Eriksson, A.E, Matthews, B.W. 登録日 1992-01-21 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences. J.Mol.Biol., 229, 1993
1L8H	DNA PROTECTION AND BINDING BY E. COLI DPS PROTEIN 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA PROTECTION DURING STARVATION PROTEIN, POTASSIUM ION 著者 Luo, J, Liu, D, White, M.A, Fox, R.O. 登録日 2002-03-20 公開日 2003-06-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 DNA Protection and Binding by E. Coli Dps Protein To be Published
1FWC	KLEBSIELLA AEROGENES UREASE, C319A VARIANT AT PH 8.5 分子名称: NICKEL (II) ION, UREASE 著者 Pearson, M.A, Karplus, P.A. 登録日 1997-04-23 公開日 1997-10-15 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease. Biochemistry, 36, 1997
1KY1	METHIONINE CORE MUTANT OF T4 LYSOZYME 分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME 著者 Gassner, N.C, Baase, W.A, Mooers, B.H, Busam, R.D, Weaver, L.H, Lindstrom, J.D, Quillin, M.L, Matthews, B.W. 登録日 2002-02-01 公開日 2003-06-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability BIOPHYS.CHEM., 100, 2003
5CRA	Structure of the SdeA DUB Domain 分子名称: METHYL 4-AMINOBUTANOATE, Polyubiquitin-B, SULFATE ION, ... 著者 Sheedlo, M.J, Qiu, J, Luo, Z.Q, Das, C. 登録日 2015-07-22 公開日 2015-11-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination. Proc.Natl.Acad.Sci.USA, 112, 2015

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