PDB: 66324 件ウェブページステータス検索Chemie searchBIRD

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5B0W	Crystal structure of the 11-cis isomer of pharaonis halorhodopsin in the absence of halide ions 分子名称: 2,3-DI-O-PHYTANLY-3-SN-GLYCERO-1-PHOSPHORYL-3'-SN-GLYCEROL-1'-PHOSPHATE, BACTERIORUBERIN, Halorhodopsin, ... 著者 Kouyama, T, Chan, S.K. 登録日 2015-11-11 公開日 2016-07-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of the 11-cis Isomer of Pharaonis Halorhodopsin: Structural Constraints on Interconversions among Different Isomeric States Biochemistry, 55, 2016
2GFS	P38 Kinase Crystal Structure in complex with RO3201195 分子名称: Mitogen-Activated Protein Kinase 14, [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE 著者 Harris, S.F, Bertrand, J, Villasenor, A. 登録日 2006-03-23 公開日 2006-04-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.752 Å) 主引用文献 Discovery of S-[5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]-methanone (RO3201195), and Orally Bioavailable and Highly Selective Inhibitor of p38 Map Kinase J.Med.Chem., 49, 2006
4PZ1	Crystal structure of a sHIP (UniProt Id: Q99XU0) mutant from Streptococcus pyogenes 分子名称: CALCIUM ION, CHLORIDE ION, sHIP 著者 Wisniewska, M, Happonen, L, Frick, I.-M, Bjorck, L, Streicher, W, Malmstrom, J, Wikstrom, M. 登録日 2014-03-28 公開日 2015-03-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Functional and structural properties of a novel protein and virulence factor (Protein sHIP) in Streptococcus pyogenes. J.Biol.Chem., 289, 2014
2GZ3	Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with NADP and aspartate-semialdehyde 分子名称: (2R)-2-AMINO-4-OXOBUTANOIC ACID, Aspartate beta-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E. 登録日 2006-05-10 公開日 2006-08-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria. J.Biol.Chem., 281, 2006
8A8M	Structure of the MAPK p38alpha in complex with its activating MAP2K MKK6 分子名称: Dual specificity mitogen-activated protein kinase kinase 6, MAGNESIUM ION, Mitogen-activated protein kinase 14, ... 著者 Bowler, M.W, Juyoux, P, Pellegrini, E. 登録日 2022-06-23 公開日 2022-07-13 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Architecture of the MKK6-p38 alpha complex defines the basis of MAPK specificity and activation. Science, 381, 2023
7ZXS	Crystal structure of DPP9 in complex with a 4-oxo-b-lactam based inhibitor, A295 分子名称: 1,2-ETHANEDIOL, 2-ethyl-2-methanoyl-~{N}-[3-[[4-(quinolin-8-ylmethyl)piperazin-1-yl]methyl]phenyl]butanamide, DI(HYDROXYETHYL)ETHER, ... 著者 Ross, B, Huber, R. 登録日 2022-05-22 公開日 2022-09-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. Angew.Chem.Int.Ed.Engl., 61, 2022
4RYV	Crystal structure of yellow lupin LLPR-10.1A protein in complex with trans-zeatin 分子名称: (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol, Protein LLPR-10.1A, SULFATE ION 著者 Dolot, R, Michalska, K, Sliwiak, J, Bujacz, G, Sikorski, M.M, Jaskolski, M. 登録日 2014-12-17 公開日 2015-12-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Crystallographic and CD probing of ligand-induced conformational changes in a plant PR-10 protein. J.Struct.Biol., 193, 2016
4TW1	Crystal structure of the octameric pore complex of the Staphylococcus aureus Bi-component Toxin LukGH 分子名称: Possible leukocidin subunit 著者 Logan, D.T, Hakansson, M, Saline, M, Kimbung, R, Badarau, A, Rouha, H, Nagy, E. 登録日 2014-06-29 公開日 2014-11-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH. J.Biol.Chem., 290, 2015
1QPH	CRYSTAL STRUCTURE OF THE A-DNA DODECAMER GACCACGTGGTC 分子名称: 5'-D(P*GP*AP*CP*CP*AP*CP*GP*TP*GP*GP*TP*CP)-3' 著者 Raaijmakers, H, Suck, D, Mayer, C. 登録日 1999-05-25 公開日 1999-05-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure Analysis of the A-DNA Dodecamer GACCACGTGGTC To be Published
2LF7	Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to Q436 分子名称: Transcription factor ETV6 著者 Coyne III, H, Green, S.M, Graves, B.J, Mcintosh, L.P. 登録日 2011-06-28 公開日 2012-05-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain. J.Mol.Biol., 421, 2012
2LF8	Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to R458 分子名称: Transcription factor ETV6 著者 Coyne III, H, Green, S.M, Graves, B.J, Mcintosh, L.P. 登録日 2011-06-28 公開日 2012-05-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain. J.Mol.Biol., 421, 2012
6ZT8	X-ray structure of mutated arabinofuranosidase 分子名称: Alpha-L-arabinofuranosidase, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... 著者 Tandrup, T, Lo Leggio, L, Zhao, J, Bissaro, B, Barbe, S, Andre, I, Dumon, C, O'Donohue, M.J, Faure, R. 登録日 2020-07-17 公開日 2021-02-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Probing the determinants of the transglycosylation/hydrolysis partition in a retaining alpha-l-arabinofuranosidase. N Biotechnol, 62, 2021
6ZT6	X-ray structure of mutated arabinofuranosidase 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-L-arabinofuranosidase 著者 Tandrup, T, Lo Leggio, L, Zhao, J, Bissaro, B, Barbe, S, Andre, I, Dumon, C, O'Donohue, M.J, Faure, R. 登録日 2020-07-17 公開日 2021-02-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Probing the determinants of the transglycosylation/hydrolysis partition in a retaining alpha-l-arabinofuranosidase. N Biotechnol, 62, 2021
8A3A	MTH1 in complex with TH013074 分子名称: 4-(4-methylphenyl)-1~{H}-quinazolin-2-one, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION 著者 Liu, H, Scaletti, E, Stenmark, P. 登録日 2022-06-07 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 MTH1 in complex with TH013074 To Be Published
8A34	MTH1 in complex with TH013071 分子名称: 5-(2-phenylphenyl)-1H-pyrimidine-2,4-dione, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... 著者 Liu, H, Scaletti, E, Stenmark, P. 登録日 2022-06-07 公開日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 MTH1 in complex with TH013071 To Be Published
8AVA	Leukotriene A4 hydrolase in complex with 4-(4-benzylphenyl)-oxazol-2-amine 分子名称: 4-[4-(phenylmethyl)phenyl]-1,3-oxazol-2-amine, ACETATE ION, GLYCEROL, ... 著者 Teder, T, Haeggstrom, J.Z. 登録日 2022-08-26 公開日 2023-05-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.354 Å) 主引用文献 Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A 4 Hydrolase. Int J Mol Sci, 24, 2023
8AWH	Leukotriene A4 hydrolase in complex with 4-(4-Benzylphenyl)-selenazol-2-amine 分子名称: 4-[4-(phenylmethyl)phenyl]-1,3-selenazol-2-amine, ACETATE ION, GLYCEROL, ... 著者 Teder, T, Haeggstrom, J.Z. 登録日 2022-08-29 公開日 2023-05-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A 4 Hydrolase. Int J Mol Sci, 24, 2023
8AAV	Human heavy chain ferritin with introduced Cys residues modified with C10 ligand 分子名称: 2-bromanyl-N-decyl-ethanamide, FE (III) ION, Ferritin heavy chain, ... 著者 Boehler, H, Beck, T. 登録日 2022-07-03 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Assembly of chemically modified protein nanocages into 3D materials for the adsorption of uremic toxins. J Mater Chem B, 11, 2022
8B5S	Crystal Structure of P. aeruginosa WaaG in complex with UDP-glucose 分子名称: UDP-glucose:(Heptosyl) LPS alpha 1,3-glucosyltransferase WaaG, URIDINE-5'-DIPHOSPHATE, URIDINE-5'-DIPHOSPHATE-GLUCOSE 著者 Scaletti, E, Gustafsson Westergren, R, Stenmark, P. 登録日 2022-09-24 公開日 2023-10-04 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and functional insights into the Pseudomonas aeruginosa glycosyltransferase WaaG and the implications for lipopolysaccharide biosynthesis. J.Biol.Chem., 299, 2023
8B5Q	Crystal Structure of P. aeruginosa WaaG in complex with UMP 分子名称: UDP-glucose:(Heptosyl) LPS alpha 1,3-glucosyltransferase WaaG, URIDINE-5'-MONOPHOSPHATE 著者 Scaletti, E, Gustafsson Westergren, R, Stenmark, P. 登録日 2022-09-24 公開日 2023-10-04 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and functional insights into the Pseudomonas aeruginosa glycosyltransferase WaaG and the implications for lipopolysaccharide biosynthesis. J.Biol.Chem., 299, 2023
8BSE	CRYSTAL STRUCTURE OF SARS-COV-2 RECEPTOR BINDING DOMAIN (RBD) in complex with 1D1 Fab 分子名称: 1D1 FAB HEAVY CHAIN, 1D1 FAB LIGHT CHAIN, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Welin, M, Kimbung, Y.R, Focht, D, Pisitkun, T. 登録日 2022-11-25 公開日 2023-05-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Efficacy of the combination of monoclonal antibodies against the SARS-CoV-2 Beta and Delta variants. Plos One, 18, 2023
8BSF	CRYSTAL STRUCTURE OF SARS-COV-2 RECEPTOR BINDING DOMAIN (RBD-beta variant) in complex with 3D2 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3D2 FAB HEAVY CHAIN, 3D2 FAB LIGHT CHAIN, ... 著者 Welin, M, Kimbung, Y.R, Focht, D, Pisitkun, T. 登録日 2022-11-25 公開日 2023-05-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Efficacy of the combination of monoclonal antibodies against the SARS-CoV-2 Beta and Delta variants. Plos One, 18, 2023
8BAN	Secretagogin (mouse) in complex with its target peptide from SNAP-25 分子名称: CALCIUM ION, Green fluorescent protein,Synaptosomal-associated protein 25, Secretagogin 著者 Schnell, R, Szodorai, E. 登録日 2022-10-11 公開日 2024-04-03 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues. Proc.Natl.Acad.Sci.USA, 121, 2024
8BAV	Secretagogin (human) in complex with its target peptide from SNAP-25 分子名称: ACETATE ION, CALCIUM ION, Green fluorescent protein,Synaptosomal-associated protein 25, ... 著者 Schnell, R, Szodorai, E. 登録日 2022-10-12 公開日 2024-04-03 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues. Proc.Natl.Acad.Sci.USA, 121, 2024
8BLR	G13D mutant of KRAS4b (2-169) bound to GDP with the switch-I in fully open conformation 分子名称: GTPase KRas, N-terminally processed, GUANOSINE-5'-DIPHOSPHATE 著者 Moche, M, Jungholm, O, Strandback, E, Ampah-Korsah, H, Nyman, T, Orwar, O. 登録日 2022-11-10 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The 1.4 A crystal structure of K-Ras4A mutant G13D in open conformation To Be Published

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