2GZ3

Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with NADP and aspartate-semialdehyde

Summary for 2GZ3

Entry DOI	10.2210/pdb2gz3/pdb
Related	2GYY 2GZ1 2GZ2
Descriptor	Aspartate beta-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2R)-2-AMINO-4-OXOBUTANOIC ACID, ... (4 entities in total)
Functional Keywords	dehydrogenase, aspartate pathway, oxidoreductase
Biological source	Streptococcus pneumoniae
Total number of polymer chains	4
Total formula weight	163596.12
Authors	Faehnle, C.R.,Le Coq, J.,Liu, X.,Viola, R.E. (deposition date: 2006-05-10, release date: 2006-08-15, Last modification date: 2023-08-30)
Primary citation	Faehnle, C.R.,Le Coq, J.,Liu, X.,Viola, R.E. Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria. J.Biol.Chem., 281:31031-31040, 2006 Cited by PubMed: 16895909 DOI: 10.1074/jbc.M605926200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation