PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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7PPG	CRYSTAL STRUCTURE OF NAMPT IN COMPLEX WITH COMPOUND 9 分子名称: 1,2-ETHANEDIOL, N-[4-[(4R)-1-cyclopentyl-4-methyl-6-oxidanylidene-4,5-dihydropyridazin-3-yl]phenyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide, Nicotinamide phosphoribosyltransferase, ... 著者 Hillig, R.C. 登録日 2021-09-13 公開日 2022-06-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 A Novel NAMPT Inhibitor-Based Antibody-Drug Conjugate Payload Class for Cancer Therapy. Bioconjug.Chem., 33, 2022
8TC7	Human asparaginyl-tRNA synthetase, apo form 分子名称: Asparagine--tRNA ligase, cytoplasmic, CHLORIDE ION, ... 著者 Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. 登録日 2023-06-30 公開日 2024-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nat Commun, 15, 2024
5BKC	Crystal structure of AAD-1 in complex with (R)-diclofop, Mn(II), and 2-oxoglutarate 分子名称: (2R)-2-{4-[(3,5-dichloropyridin-2-yl)oxy]phenoxy}propanoic acid, (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, 2-OXOGLUTARIC ACID, ... 著者 Chekan, J.R, Nair, S.K. 登録日 2019-06-02 公開日 2019-06-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proc.Natl.Acad.Sci.USA, 116, 2019
5BNR	E. coli Fabh with small molecule inhibitor 2 分子名称: 1-{5-[2-fluoro-5-(hydroxymethyl)phenyl]pyridin-2-yl}piperidine-4-carboxylic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 3 著者 Kazmirski, S.L, McKinney, D.C. 登録日 2015-05-26 公開日 2016-05-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Antibacterial FabH Inhibitors with Mode of Action Validated in Haemophilus influenzae by in Vitro Resistance Mutation Mapping. Acs Infect Dis., 2, 2016
2ZWE	Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 40 minutes 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2008-12-03 公開日 2009-12-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase To be Published
1NU2	Crystal structure of the murine Disabled-1 (Dab1) PTB domain-ApoER2 peptide-PI-4,5P2 ternary complex 分子名称: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Disabled homolog 1, peptide derived from murine Apolipoprotein E Receptor-2 著者 Stolt, P.C, Jeon, H, Song, H.K, Herz, J, Eck, M.J, Blacklow, S.C. 登録日 2003-01-30 公開日 2003-04-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Origins of Peptide Selectivity and Phosphoinositide Binding Revealed by Structures of Disabled-1 PTB Domain Complexes Structure, 11, 2003
5BMM	Src in complex with DNA-templated macrocyclic inhibitor MC25b 分子名称: Proto-oncogene tyrosine-protein kinase Src, macrocyclic inhibitor MC25b 著者 Georghiou, G, Guja, K.E, Aleem, S, Kleiner, R.E, Liu, D.R, Miller, W.T, Garcia-Diaz, M, Seeliger, M.A. 登録日 2015-05-22 公開日 2016-09-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles. Cell Chem Biol, 23, 2016
1NSE	BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ... 著者 Raman, C.S, Li, H, Martasek, P, Kral, V, Masters, B.S.S, Poulos, T.L. 登録日 1998-05-14 公開日 1999-05-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center. Cell(Cambridge,Mass.), 95, 1998
7PFY	Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2241 分子名称: Inhibitor MI-2241, Serine protease NS3, Serine protease subunit NS2B 著者 Huber, S, Heine, A, Steinmetzer, T. 登録日 2021-08-12 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors. J.Med.Chem., 65, 2022
2Z9V	Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxamine 分子名称: 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, Aspartate aminotransferase, GLYCEROL, ... 著者 Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. 登録日 2007-09-26 公開日 2007-11-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J.Biol.Chem., 283, 2008
7PEK	Crystal structure of Triosephosphate Isomerase C216A mutant from Schizosaccharomyces pombe (SpTIM C216A) 分子名称: GLYCEROL, PHOSPHATE ION, SODIUM ION, ... 著者 Romero-Romero, S, Garza-Ramos, G. 登録日 2021-08-10 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Crystal structure of Triosephosphate Isomerase from Schizosaccharomyces pombe (SpTIM C216A) To Be Published
2Z9J	Complex structure of SARS-CoV 3C-like protease with EPDTC 分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, zinc(II)hydrogensulfide 著者 Lee, C.C, Wang, A.H. 登録日 2007-09-20 公開日 2007-12-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors. Febs Lett., 581, 2007
2RPS	Solution structure of a novel insect chemokine isolated from integument 分子名称: Chemokine 著者 Kamiya, M, Nakatogawa, S, Oda, Y, Kamijima, T, Aizawa, T, Demura, M, Hayakawa, Y, Kawano, K. 登録日 2008-07-28 公開日 2009-06-16 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 A novel peptide mediates aggregation and migration of hemocytes from an insect Curr.Biol., 19, 2009
2RPV	Solution Structure of GB1 with LBT probe 分子名称: Immunoglobulin G-binding protein G, LANTHANUM (III) ION 著者 Saio, T, Ogura, K, Yokochi, M, Kobashigawa, Y, Inagaki, F. 登録日 2008-10-28 公開日 2009-09-15 最終更新日 2021-11-10 実験手法 SOLUTION NMR 主引用文献 Two-point anchoring of a lanthanide-binding peptide to a target protein enhances the paramagnetic anisotropic effect J.Biomol.Nmr, 44, 2009
7PXV	LsAA9_A chemically reduced with ascorbic acid (high X-ray dose) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity 9, CHLORIDE ION, ... 著者 Tandrup, T, Muderspach, S.J, Banerjee, S, Ipsen, J, Johansen, K.S, Lo Leggio, L. 登録日 2021-10-08 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Changes in active-site geometry on X-ray photoreduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding. Iucrj, 9, 2022
2ZAV	Arginase I (homo sapiens): native and unliganded structure at 1.70 A resolution 分子名称: Arginase-1, MANGANESE (II) ION 著者 Di Costanzo, L, Christianson, D.W. 登録日 2007-10-11 公開日 2007-10-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster J.Am.Chem.Soc., 129, 2007
3E8D	Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors 分子名称: 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1S)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol, Glycogen synthase kinase-3 beta peptide, RAC-beta serine/threonine-protein kinase 著者 Concha, N.O, Elkins, P.A, Smallwood, A, Ward, P. 登録日 2008-08-19 公開日 2008-10-14 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Aminofurazans as potent inhibitors of AKT kinase Bioorg.Med.Chem.Lett., 19, 2009
2RH3	Crystal structure of plasmid pTiC58 VirC2 分子名称: Protein virC2 著者 Lu, J, Glover, J.N.M. 登録日 2007-10-05 公開日 2008-10-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Agrobacterium tumefaciens VirC2 enhances T-DNA transfer and virulence through its C-terminal ribbon-helix-helix DNA-binding fold Proc.Natl.Acad.Sci.USA, 106, 2009
2DCG	MOLECULAR STRUCTURE OF A LEFT-HANDED DOUBLE HELICAL DNA FRAGMENT AT ATOMIC RESOLUTION 分子名称: DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), MAGNESIUM ION, SPERMINE 著者 Wang, A.H.-J, Quigley, G.J, Kolpak, F.J, Crawford, J.L, Van Boom, J.H, Van Der Marel, G.A, Rich, A. 登録日 1988-08-29 公開日 1989-01-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (0.9 Å) 主引用文献 Molecular structure of a left-handed double helical DNA fragment at atomic resolution. Nature, 282, 1979
7PEF	Crystal structure of IpgC in complex with DMSO 分子名称: CHLORIDE ION, Chaperone protein IpgC, DIMETHYL SULFOXIDE, ... 著者 Gardonyi, M, Heine, A, Klebe, G. 登録日 2021-08-10 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Crystal structure of IpgC in complex with DMSO To be published
5BPL	Crystal structure of ADP and Pi bound human Hsp70 NBD mutant R272K. 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Narayanan, D, Engh, R.A. 登録日 2015-05-28 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Nucleotide binding to variants of the HSP70-NBD. To Be Published
2DCM	The Crystal Structure of S603A Mutated Prolyl Tripeptidyl Aminopeptidase Complexed with Substrate 分子名称: GLYCYLALANYL-N-2-NAPHTHYL-L-PROLINEAMIDE, dipeptidyl aminopeptidase IV, putative 著者 Nakajima, Y, Ito, K, Xu, Y, Yamada, N, Onohara, Y, Yoshimoto, T. 登録日 2006-01-09 公開日 2006-09-19 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure and Mechanism of Tripeptidyl Activity of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis J.Mol.Biol., 362, 2006
4G5F	Pantothenate synthetase in complex with racemate (2S)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID and (2R)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID 分子名称: (2R)-2,3-dihydro-1,4-benzodioxine-2-carboxylic acid, (2S)-2,3-dihydro-1,4-benzodioxine-2-carboxylic acid, 1,2-ETHANEDIOL, ... 著者 Silvestre, H.L, Blundell, T.L, Abell, C, Ciulli, A. 登録日 2012-07-17 公開日 2013-07-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery. Proc.Natl.Acad.Sci.USA, 110, 2013
5EM0	Crystal structure of mugwort allergen Art v 4 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Pollen allergen Art v 4.01, SODIUM ION 著者 Offermann, L.R, Perdue, M.L, Chruszcz, M. 登録日 2015-11-05 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2. J.Biol.Chem., 291, 2016
8TXR	E. coli ExoVII(H238A) 分子名称: Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease 7 small subunit 著者 Liu, C, Berger, J.M. 登録日 2023-08-24 公開日 2024-01-31 最終更新日 2024-02-07 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of Escherichia coli exonuclease VII. Proc.Natl.Acad.Sci.USA, 121, 2024

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