PDB: 8861 件ウェブページステータス検索Chemie searchBIRD

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5D2O	2009 H1N1 PA endonuclease mutant F105S 分子名称: MANGANESE (II) ION, Polymerase acidic protein 著者 Kumar, G, White, S.W. 登録日 2015-08-05 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc.Natl.Acad.Sci.USA, 113, 2016
5B31	The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.1. 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... 著者 Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. 登録日 2016-02-08 公開日 2016-08-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
9ANT	ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX 分子名称: ANTENNAPEDIA HOMEODOMAIN, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ... 著者 Fraenkel, E, Pabo, C.O. 登録日 1998-07-02 公開日 1998-10-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Comparison of X-ray and NMR structures for the Antennapedia homeodomain-DNA complex. Nat.Struct.Biol., 5, 1998
6G4W	Cryo-EM structure of a late human pre-40S ribosomal subunit - State A 分子名称: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-28 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
2DTU	Crystal structure of the beta hairpin loop deletion variant of RB69 gp43 in complex with DNA containing an abasic site analog 分子名称: 5'-D(*CP*GP*(3DR)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*GP*A)-3', DNA polymerase 著者 Aller, P, Hogg, M, Konigsberg, W, Wallace, S.S, Doublie, S. 登録日 2006-07-15 公開日 2006-12-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. J.Biol.Chem., 282, 2007
2W9B	Binary complex of Dpo4 bound to N2,N2-dimethyl-deoxyguanosine modified DNA 分子名称: 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*DOCP)-3', 5'-D(*TP*CP*AP*TP*M2GP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', DNA POLYMERASE IV, ... 著者 Eoff, R.L, Zhang, H, Kosekov, I.D, Rizzo, C.J, Egli, M, Guengerich, F.P. 登録日 2009-01-22 公開日 2009-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structure-Function Relationships in Miscoding by Sulfolobus Solfataricus DNA Polymerase Dpo4: Guanine N2,N2-Dimethyl Substitution Produces Inactive and Miscoding Polymerase Complexes. J.Biol.Chem., 284, 2009
5OF3	Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus. 分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA primase large subunit PriL, DNA primase small subunit PriS, ... 著者 Pellegrini, L, Holzer, S. 登録日 2017-07-10 公開日 2017-11-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.906 Å) 主引用文献 Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster. Nat Commun, 8, 2017
8RC0	Structure of the human 20S U5 snRNP 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Schneider, S, Galej, W.P. 登録日 2023-12-05 公開日 2024-03-27 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of the human 20S U5 snRNP. Nat.Struct.Mol.Biol., 31, 2024
8Q91	Structure of the human 20S U5 snRNP core 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Schneider, S, Galej, W.P. 登録日 2023-08-19 公開日 2024-03-27 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of the human 20S U5 snRNP. Nat.Struct.Mol.Biol., 31, 2024
7Y38	Molecular architecture of the chikungunya virus replication complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Protease nsP2, ... 著者 Tan, Y.B, Luo, D. 登録日 2022-06-10 公開日 2022-12-14 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Molecular architecture of the Chikungunya virus replication complex. Sci Adv, 8, 2022
6G53	Cryo-EM structure of a late human pre-40S ribosomal subunit - State E 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-28 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6G5I	Cryo-EM structure of a late human pre-40S ribosomal subunit - State R 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-29 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6G51	Cryo-EM structure of a late human pre-40S ribosomal subunit - State D 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-28 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
5N65	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9h 分子名称: 2-phenyl-~{N}4-(2-thiophen-2-ylethyl)quinazoline-4,7-diamine, Mitogen-activated protein kinase 14 著者 Buehrmann, M, Mueller, M.P, Wiedemann, B, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
5N64	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9g 分子名称: 2-phenyl-~{N}4-(thiophen-2-ylmethyl)quinazoline-4,7-diamine, Mitogen-activated protein kinase 14 著者 Buehrmann, M, Mueller, M.P, Wiedemann, B, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
5N66	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9j 分子名称: 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, Mitogen-activated protein kinase 14, ~{N}4-[[4-(cyclopropylmethyl)furan-2-yl]methyl]-2-phenyl-quinazoline-4,7-diamine 著者 Buehrmann, M, Mueller, M.P, Wiedemann, B, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
5N67	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9l 分子名称: 1-[4-[4-[7-azanyl-4-(2-phenylethylamino)quinazolin-2-yl]phenyl]piperazin-1-yl]ethanone, Mitogen-activated protein kinase 14 著者 Buehrmann, M, Mueller, M.P, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
5N68	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9m 分子名称: 2-(4-morpholin-4-ylphenyl)-~{N}4-(2-phenylethyl)quinazoline-4,7-diamine, Mitogen-activated protein kinase 14 著者 Buehrmann, M, Mueller, M.P, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
5N63	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9c 分子名称: Mitogen-activated protein kinase 14, ~{N}4-[(4-fluorophenyl)methyl]-2-phenyl-quinazoline-4,7-diamine 著者 Buehrmann, M, Mueller, M.P, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
2DY4	Crystal structure of RB69 GP43 in complex with DNA containing Thymine Glycol 分子名称: 5'-D(*CP*GP*(CTG)P*GP*GP*AP*AP*TP*GP*A*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*T*CP*AP*TP*TP*CP*CP*A)-3', DNA polymerase 著者 Aller, P, Rould, M.A, Hogg, M, Wallace, S.S, Doublie, S. 登録日 2006-09-06 公開日 2007-01-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Proc.Natl.Acad.Sci.USA, 104, 2007
5X7X	The crystal structure of the nucleosome containing H3.3 at 2.18 angstrom resolution 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... 著者 Arimura, Y, Taguchi, H, Kurumizaka, H. 登録日 2017-02-27 公開日 2017-04-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.184 Å) 主引用文献 Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8 Biochemistry, 56, 2017
6G5H	Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-29 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
4CV4	PIH N-terminal domain 分子名称: COBALT (II) ION, PIH1 DOMAIN-CONTAINING PROTEIN 1, SULFATE ION 著者 Morgan, R.M, Roe, S.M. 登録日 2014-03-23 公開日 2014-05-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1. Structure, 22, 2014
6YBS	Structure of a human 48S translational initiation complex - head 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... 著者 Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. 登録日 2020-03-17 公開日 2020-09-16 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of a human 48Stranslational initiation complex. Science, 369, 2020
4TLR	NS5b in complex with lactam-thiophene carboxylic acids 分子名称: 3-{(2R,5R)-5-cyclohexyl-2-[(2R)-2-hydroxypropyl]-3-oxomorpholin-4-yl}-5-(3,3-dimethylbut-1-yn-1-yl)thiophene-2-carboxylic acid, 5-cyclopropyl-2-(4-fluorophenyl)-6-[(2-hydroxyethyl)(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide, NS5b 著者 Chopra, R. 登録日 2014-05-30 公開日 2014-12-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors. Bioorg.Med.Chem.Lett., 24, 2014

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