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6A1O
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BU of 6a1o by Molmil
Crystal structures of disordered Z-type helices
分子名称: DNA (5'-D(P*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*A)-3'), DNA (5'-D(P*TP*G)-3'), ...
著者Karthik, S, Mandal, P.K, Thirugnanasambandam, A, Gautham, N.
登録日2018-06-07
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Crystal structures of disordered Z-type helices.
Nucleosides Nucleotides Nucleic Acids, 38, 2019
6ZYJ
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BU of 6zyj by Molmil
Crystal structure of Hsc70 ATPase domain in complex with ADP and calcium
分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
著者Yan, Y, Preissler, S, Ron, D.
登録日2020-08-01
公開日2020-12-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes.
Elife, 9, 2020
6A1Q
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BU of 6a1q by Molmil
Crystal structures of disordered Z-type helices
分子名称: DNA (5'-D(P*CP*AP*CP*A)-3'), DNA (5'-D(P*TP*GP*TP*G)-3')
著者Karthik, S, Mandal, P.K, Thirugnanasambandam, A, Gautham, N.
登録日2018-06-07
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Crystal structures of disordered Z-type helices.
Nucleosides Nucleotides Nucleic Acids, 38, 2019
7A4U
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BU of 7a4u by Molmil
Crystal structure of lid-truncated apo BiP in an oligomeric state
分子名称: Endoplasmic reticulum chaperone BiP, GLYCEROL
著者Perera, L.A, Ron, D.
登録日2020-08-20
公開日2020-12-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes.
Elife, 9, 2020
7A4V
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BU of 7a4v by Molmil
Crystal structure of lid-truncated ADP-bound BiP in an oligomeric state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Endoplasmic reticulum chaperone BiP, GLYCEROL, ...
著者Perera, L.A, Ron, D.
登録日2020-08-20
公開日2020-12-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes.
Elife, 9, 2020
6ZYH
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BU of 6zyh by Molmil
Crystal structure of GRP78 (70kDa heat shock protein 5 / BiP) ATPase domain in complex with ADP and calcium
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Endoplasmic reticulum chaperone BiP
著者Yan, Y, Preissler, S, Ron, D.
登録日2020-08-01
公開日2020-12-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes.
Elife, 9, 2020
7M2E
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BU of 7m2e by Molmil
Crystal structure of BPTF bromodomain in complex with CB02-092
分子名称: 4-chloro-5-{4-[2-(dimethylamino)ethyl]anilino}-2-methylpyridazin-3(2H)-one, Nucleosome-remodeling factor subunit BPTF
著者Nithianantham, S, Fischer, M.
登録日2021-03-16
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition
J.Med.Chem., 64, 2021
3I1C
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BU of 3i1c by Molmil
Crystal Structure of a Novel Engineered Diels-Alderase: DA_20_00_A74I
分子名称: Diisopropyl-fluorophosphatase, GLYCEROL
著者Lambert, A.R, Stoddard, B.L.
登録日2009-06-26
公開日2009-08-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction.
Science, 329, 2010
7Y01
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BU of 7y01 by Molmil
Crystal structure of ZmMCM10 in complex with 16nt ssDNA at 2.8. Angstrom resolution
分子名称: DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), MCM10 minichromosome maintenance deficient 10, ZINC ION
著者Du, X, Du, J.
登録日2022-06-03
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献AtMCM10 promotes DNA replication-coupled nucleosome assembly in Arabidopsis.
J Integr Plant Biol, 65, 2023
3VOK
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BU of 3vok by Molmil
X-ray Crystal Structure of Wild Type HrtR in the Apo Form with the Target DNA.
分子名称: 5'-D(*AP*TP*GP*AP*CP*AP*CP*TP*GP*TP*GP*TP*CP*AP*T)-3', Transcriptional regulator
著者Sawai, H, Sugimoto, H, Shiro, Y, Aono, S.
登録日2012-01-27
公開日2012-07-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Transcriptional Regulation of Heme Homeostasis in Lactococcus lactis.
J.Biol.Chem., 287, 2012
3VOX
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BU of 3vox by Molmil
X-ray Crystal Structure of Wild Type HrtR in the Apo Form
分子名称: Transcriptional regulator
著者Sawai, H, Sugimoto, H, Shiro, Y, Aono, S.
登録日2012-02-23
公開日2012-07-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis for the Transcriptional Regulation of Heme Homeostasis in Lactococcus lactis.
J.Biol.Chem., 287, 2012
8B9O
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BU of 8b9o by Molmil
Structure of the C-terminal domain of ClpC2 from Mycobacterium smegmatis
分子名称: Clp amino terminal domain protein, phospho-arginine
著者Meinhart, A, Hoi, D.M, Clausen, T.
登録日2022-10-06
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023
8B9U
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BU of 8b9u by Molmil
Structure of ClpC1 NTD from Mycobacterium tuberculosis
分子名称: (MLE)V(MAA)(E9M)G, ATP-dependent Clp protease ATP-binding subunit ClpC1, FORMIC ACID
著者Meinhart, A, Hoi, D.M, Clausen, T.
登録日2022-10-10
公開日2023-07-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023
3HKY
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BU of 3hky by Molmil
HCV NS5B polymerase genotype 1b in complex with 1,5 benzodiazepine 6
分子名称: (11S)-10-[(2,5-dimethyl-1,3-oxazol-4-yl)carbonyl]-11-{2-fluoro-4-[(2-methylprop-2-en-1-yl)oxy]phenyl}-3,3-dimethyl-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide, CHLORIDE ION, RNA-directed RNA polymerase, ...
著者Nyanguile, O, De Bondt, H.L.
登録日2009-05-26
公開日2010-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus
J.Virol., 84, 2010
3HKW
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BU of 3hkw by Molmil
HCV NS5B genotype 1a in complex with 1,5 benzodiazepine inhibitor 6
分子名称: (11S)-10-[(2,5-dimethyl-1,3-oxazol-4-yl)carbonyl]-11-{2-fluoro-4-[(2-methylprop-2-en-1-yl)oxy]phenyl}-3,3-dimethyl-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide, GLYCEROL, NS5B RNA-dependent RNA polymerase, ...
著者Nyanguile, O, De Bondt, H.L.
登録日2009-05-26
公開日2010-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus
J.Virol., 84, 2010
3VP5
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BU of 3vp5 by Molmil
X-ray Crystal Structure of Wild Type HrtR in the Holo Form
分子名称: CACODYLATE ION, PROTOPORPHYRIN IX CONTAINING FE, Transcriptional regulator
著者Sawai, H, Sugimoto, H, Shiro, Y, Aono, S.
登録日2012-02-23
公開日2012-07-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis for the Transcriptional Regulation of Heme Homeostasis in Lactococcus lactis.
J.Biol.Chem., 287, 2012
7Y61
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BU of 7y61 by Molmil
Cryo-EM structure of the two CAF1LCs bound right-handed Di-tetrasome
分子名称: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
著者Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M.
登録日2022-06-18
公開日2023-08-16
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7Y60
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BU of 7y60 by Molmil
Cryo-EM structure of human CAF1LC bound right-handed Di-tetrasome
分子名称: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
著者Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M.
登録日2022-06-18
公開日2023-08-16
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7Y5W
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BU of 7y5w by Molmil
Cryo-EM structure of the left-handed Di-tetrasome
分子名称: Histone H3.1, Histone H4, Widom 601 DNA (147-MER)
著者Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M.
登録日2022-06-17
公開日2023-08-16
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
3HIB
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BU of 3hib by Molmil
Crystal structure of the second Sec63 domain of yeast Brr2
分子名称: Pre-mRNA-splicing helicase BRR2
著者Zhang, L, Xu, T, Zhao, R.
登録日2009-05-19
公開日2009-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2.
Nat.Struct.Mol.Biol., 16, 2009
3TOG
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BU of 3tog by Molmil
HIV-1 Protease - Epoxydic Inhibitor Complex (pH 9 - Monoclinic Crystal form P21)
分子名称: (S)-N-((2S,3S,4R,5R)-4-amino-3,5-dihydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-phenoxyacetamido)butanamide, DIMETHYL SULFOXIDE, Gag-Pol polyprotein
著者Geremia, S, Olajuyigbe, F.M, Demitri, N.
登録日2011-09-05
公開日2012-08-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Developing HIV-1 Protease Inhibitors through Stereospecific Reactions in Protein Crystals.
Molecules, 21, 2016
3OAK
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BU of 3oak by Molmil
Crystal structure of a Spn1 (Iws1)-Spt6 complex
分子名称: Transcription elongation factor SPT6, Transcription factor IWS1
著者McDonald, S.M, Close, D, Hill, C.P.
登録日2010-08-05
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure and biological importance of the spn1-spt6 interaction, and its regulatory role in nucleosome binding.
Mol.Cell, 40, 2010
3TOF
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BU of 3tof by Molmil
HIV-1 Protease - Epoxydic Inhibitor Complex (pH 6 - Orthorombic Crystal form P212121)
分子名称: (S)-N-((1R,2S)-1-((2R,3R)-3-benzyloxiran-2-yl)-1-hydroxy-3-phenylpropan-2-yl)-3-methyl-2-(2-phenoxyacetamido)butanamide, ACETATE ION, DIMETHYL SULFOXIDE, ...
著者Geremia, S, Olajuyigbe, F.M, Ajele, J.O, Demitri, N, Randaccio, L, Wuerges, J, Benedetti, L, Campaner, P, Berti, F.
登録日2011-09-05
公開日2012-08-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Developing HIV-1 Protease Inhibitors through Stereospecific Reactions in Protein Crystals.
Molecules, 21, 2016
1ZZE
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BU of 1zze by Molmil
X-ray Structure of NADPH-dependent Carbonyl Reductase from Sporobolomyces salmonicolor
分子名称: Aldehyde reductase II, SULFATE ION
著者Kamitori, S, Iguchi, A, Ohtaki, A, Yamada, M, Kita, K.
登録日2005-06-14
公開日2005-09-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray Structures of NADPH-dependent Carbonyl Reductase from Sporobolomyces salmonicolor Provide Insights into Stereoselective Reductions of Carbonyl Compounds
J.Mol.Biol., 352, 2005
3C7C
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BU of 3c7c by Molmil
A structural basis for substrate and stereo selectivity in octopine dehydrogenase (ODH-NADH-L-Arginine)
分子名称: ARGININE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Octopine dehydrogenase
著者Smits, S.H.J, Mueller, A, Schmitt, L, Grieshaber, M.K.
登録日2008-02-07
公開日2008-07-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A structural basis for substrate selectivity and stereoselectivity in octopine dehydrogenase from Pecten maximus.
J.Mol.Biol., 381, 2008

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