6A1O
| Crystal structures of disordered Z-type helices | 分子名称: | DNA (5'-D(P*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*A)-3'), DNA (5'-D(P*TP*G)-3'), ... | 著者 | Karthik, S, Mandal, P.K, Thirugnanasambandam, A, Gautham, N. | 登録日 | 2018-06-07 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Crystal structures of disordered Z-type helices. Nucleosides Nucleotides Nucleic Acids, 38, 2019
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6ZYJ
| Crystal structure of Hsc70 ATPase domain in complex with ADP and calcium | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | 著者 | Yan, Y, Preissler, S, Ron, D. | 登録日 | 2020-08-01 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes. Elife, 9, 2020
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6A1Q
| Crystal structures of disordered Z-type helices | 分子名称: | DNA (5'-D(P*CP*AP*CP*A)-3'), DNA (5'-D(P*TP*GP*TP*G)-3') | 著者 | Karthik, S, Mandal, P.K, Thirugnanasambandam, A, Gautham, N. | 登録日 | 2018-06-07 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Crystal structures of disordered Z-type helices. Nucleosides Nucleotides Nucleic Acids, 38, 2019
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7A4U
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7A4V
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6ZYH
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7M2E
| Crystal structure of BPTF bromodomain in complex with CB02-092 | 分子名称: | 4-chloro-5-{4-[2-(dimethylamino)ethyl]anilino}-2-methylpyridazin-3(2H)-one, Nucleosome-remodeling factor subunit BPTF | 著者 | Nithianantham, S, Fischer, M. | 登録日 | 2021-03-16 | 公開日 | 2022-02-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition J.Med.Chem., 64, 2021
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3I1C
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7Y01
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3VOK
| X-ray Crystal Structure of Wild Type HrtR in the Apo Form with the Target DNA. | 分子名称: | 5'-D(*AP*TP*GP*AP*CP*AP*CP*TP*GP*TP*GP*TP*CP*AP*T)-3', Transcriptional regulator | 著者 | Sawai, H, Sugimoto, H, Shiro, Y, Aono, S. | 登録日 | 2012-01-27 | 公開日 | 2012-07-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Basis for the Transcriptional Regulation of Heme Homeostasis in Lactococcus lactis. J.Biol.Chem., 287, 2012
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3VOX
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8B9O
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8B9U
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3HKY
| HCV NS5B polymerase genotype 1b in complex with 1,5 benzodiazepine 6 | 分子名称: | (11S)-10-[(2,5-dimethyl-1,3-oxazol-4-yl)carbonyl]-11-{2-fluoro-4-[(2-methylprop-2-en-1-yl)oxy]phenyl}-3,3-dimethyl-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide, CHLORIDE ION, RNA-directed RNA polymerase, ... | 著者 | Nyanguile, O, De Bondt, H.L. | 登録日 | 2009-05-26 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | 1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus J.Virol., 84, 2010
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3HKW
| HCV NS5B genotype 1a in complex with 1,5 benzodiazepine inhibitor 6 | 分子名称: | (11S)-10-[(2,5-dimethyl-1,3-oxazol-4-yl)carbonyl]-11-{2-fluoro-4-[(2-methylprop-2-en-1-yl)oxy]phenyl}-3,3-dimethyl-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide, GLYCEROL, NS5B RNA-dependent RNA polymerase, ... | 著者 | Nyanguile, O, De Bondt, H.L. | 登録日 | 2009-05-26 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | 1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus J.Virol., 84, 2010
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3VP5
| X-ray Crystal Structure of Wild Type HrtR in the Holo Form | 分子名称: | CACODYLATE ION, PROTOPORPHYRIN IX CONTAINING FE, Transcriptional regulator | 著者 | Sawai, H, Sugimoto, H, Shiro, Y, Aono, S. | 登録日 | 2012-02-23 | 公開日 | 2012-07-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis for the Transcriptional Regulation of Heme Homeostasis in Lactococcus lactis. J.Biol.Chem., 287, 2012
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7Y61
| Cryo-EM structure of the two CAF1LCs bound right-handed Di-tetrasome | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | 著者 | Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. | 登録日 | 2022-06-18 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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7Y60
| Cryo-EM structure of human CAF1LC bound right-handed Di-tetrasome | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | 著者 | Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M. | 登録日 | 2022-06-18 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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7Y5W
| Cryo-EM structure of the left-handed Di-tetrasome | 分子名称: | Histone H3.1, Histone H4, Widom 601 DNA (147-MER) | 著者 | Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. | 登録日 | 2022-06-17 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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3HIB
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3TOG
| HIV-1 Protease - Epoxydic Inhibitor Complex (pH 9 - Monoclinic Crystal form P21) | 分子名称: | (S)-N-((2S,3S,4R,5R)-4-amino-3,5-dihydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-phenoxyacetamido)butanamide, DIMETHYL SULFOXIDE, Gag-Pol polyprotein | 著者 | Geremia, S, Olajuyigbe, F.M, Demitri, N. | 登録日 | 2011-09-05 | 公開日 | 2012-08-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Developing HIV-1 Protease Inhibitors through Stereospecific Reactions in Protein Crystals. Molecules, 21, 2016
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3OAK
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3TOF
| HIV-1 Protease - Epoxydic Inhibitor Complex (pH 6 - Orthorombic Crystal form P212121) | 分子名称: | (S)-N-((1R,2S)-1-((2R,3R)-3-benzyloxiran-2-yl)-1-hydroxy-3-phenylpropan-2-yl)-3-methyl-2-(2-phenoxyacetamido)butanamide, ACETATE ION, DIMETHYL SULFOXIDE, ... | 著者 | Geremia, S, Olajuyigbe, F.M, Ajele, J.O, Demitri, N, Randaccio, L, Wuerges, J, Benedetti, L, Campaner, P, Berti, F. | 登録日 | 2011-09-05 | 公開日 | 2012-08-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Developing HIV-1 Protease Inhibitors through Stereospecific Reactions in Protein Crystals. Molecules, 21, 2016
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1ZZE
| X-ray Structure of NADPH-dependent Carbonyl Reductase from Sporobolomyces salmonicolor | 分子名称: | Aldehyde reductase II, SULFATE ION | 著者 | Kamitori, S, Iguchi, A, Ohtaki, A, Yamada, M, Kita, K. | 登録日 | 2005-06-14 | 公開日 | 2005-09-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-ray Structures of NADPH-dependent Carbonyl Reductase from Sporobolomyces salmonicolor Provide Insights into Stereoselective Reductions of Carbonyl Compounds J.Mol.Biol., 352, 2005
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3C7C
| A structural basis for substrate and stereo selectivity in octopine dehydrogenase (ODH-NADH-L-Arginine) | 分子名称: | ARGININE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Octopine dehydrogenase | 著者 | Smits, S.H.J, Mueller, A, Schmitt, L, Grieshaber, M.K. | 登録日 | 2008-02-07 | 公開日 | 2008-07-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A structural basis for substrate selectivity and stereoselectivity in octopine dehydrogenase from Pecten maximus. J.Mol.Biol., 381, 2008
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