4BGD

Crystal structure of Brr2 in complex with the Jab1/MPN domain of Prp8

Summary for 4BGD

Entry DOI	10.2210/pdb4bgd/pdb
Descriptor	PRE-MRNA-SPLICING HELICASE BRR2, PRE-MRNA-SPLICING FACTOR 8, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywords	transcription, spliceosome, rna helicase, u5 snrnp, retinitis pigmentosa
Biological source	SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) More
Cellular location	Nucleus (Probable): P32639 Nucleus: P33334
Total number of polymer chains	2
Total formula weight	224760.37
Authors	Nguyen, T.H.D.,Li, J.,Nagai, K. (deposition date: 2013-03-25, release date: 2013-05-29, Last modification date: 2023-12-20)
Primary citation	Nguyen, T.H.D.,Li, J.,Galej, W.P.,Oshikane, H.,Newman, A.J.,Nagai, K. Structural Basis of Brr2-Prp8 Interactions and Implications for U5 Snrnp Biogenesis and the Spliceosome Active Site Structure, 21:910-, 2013 Cited by PubMed: 23727230 DOI: 10.1016/J.STR.2013.04.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation