PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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1PYS	PHENYLALANYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS 分子名称: MAGNESIUM ION, PHENYLALANYL-TRNA SYNTHETASE 著者 Safro, M, Mosyak, L, Goldgur, Y, Reshetnikova, L, Delarue, M. 登録日 1996-11-14 公開日 1997-11-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of phenylalanyl-tRNA synthetase from Thermus thermophilus. Nat.Struct.Biol., 2, 1995
3U3A	structure of Human Carbonic Anhydrase II V143I 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION 著者 West, D, Mckenna, R. 登録日 2011-10-05 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.549 Å) 主引用文献 Structural Analysis of Human Carbonic Anhydrase II Binding Pocket To be Published
6I2C	Crystal Structure of the Protein-Kinase A catalytic subunit from Cricetulus Griseus in complex with compounds RKp182 and Fasudil 分子名称: 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, UPF0418 protein FAM164A, beta-D-ribopyranose, ... 著者 Mueller, J.M, Heine, A, Klebe, G. 登録日 2018-11-01 公開日 2019-05-15 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019
4IY0	Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, Metal transporter CNNM2 著者 Corral-Rodriguez, M.A, Stuiver, M, Encinar, J.A, Spiwok, V, Gomez-Garcia, I, Oyenarte, I, Ereno-Orbea, J, Terashima, H, Accardi, A, Diercks, T, Muller, D, Martinez-Cruz, L.A. 登録日 2013-01-28 公開日 2014-03-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4 To be Published
3U5P	Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-28)K9me3K14acK18acK23ac histone peptide 分子名称: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION 著者 Wang, Z, Patel, D.J. 登録日 2011-10-11 公開日 2012-01-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A poised chromatin platform for TGF-beta access to master regulators Cell(Cambridge,Mass.), 147, 2011
6I3F	Crystal structure of the complex of human angiotensinogen and renin at 2.55 Angstrom 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen, ... 著者 Yan, Y, Read, R.J. 登録日 2018-11-06 公開日 2018-12-26 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for the specificity of renin-mediated angiotensinogen cleavage. J. Biol. Chem., 294, 2019
6IIU	Crystal structure of the human thromboxane A2 receptor bound to ramatroban 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid, CHOLESTEROL, ... 著者 Fan, H, Zhao, Q, Wu, B. 登録日 2018-10-07 公開日 2018-12-19 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for ligand recognition of the human thromboxane A2receptor. Nat. Chem. Biol., 15, 2019
1TK8	T7 DNA polymerase ternary complex with 8 oxo guanosine and dAMP at the elongation site 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*AP*(8OG)P*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', ... 著者 Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. 登録日 2004-06-08 公開日 2004-08-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
1SRX	THREE-DIMENSIONAL STRUCTURE OF ESCHERICHIA COLI THIOREDOXIN-S2 TO 2.8 ANGSTROMS RESOLUTION 分子名称: THIOREDOXIN 著者 Soderberg, B.-O. 登録日 1976-05-06 公開日 1976-05-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Three-dimensional structure of Escherichia coli thioredoxin-S2 to 2.8 A resolution. Proc.Natl.Acad.Sci.USA, 72, 1975
2ACU	TYROSINE-48 IS THE PROTON DONOR AND HISTIDINE-110 DIRECTS SUBSTRATE STEREOCHEMICAL SELECTIVITY IN THE REDUCTION REACTION OF HUMAN ALDOSE REDUCTASE: ENZYME KINETICS AND THE CRYSTAL STRUCTURE OF THE Y48H MUTANT ENZYME 分子名称: ALDOSE REDUCTASE, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Bohren, K.M, Grimshaw, C.E, Lai, C.-J, Gabbay, K.H, Petsko, G.A, Harrison, D.H, Ringe, D. 登録日 1994-04-15 公開日 1994-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme. Biochemistry, 33, 1994
4IWK	Crystal structure of iron soaked (overnight) ferritin from Pseudo-nitzschia multiseries 分子名称: FE (III) ION, Ferritin 著者 Pfaffen, S, Murphy, M.E.P. 登録日 2013-01-23 公開日 2013-03-20 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Mechanism of ferrous iron binding and oxidation by ferritin from a pennate diatom. J.Biol.Chem., 288, 2013
3NJ9	Crystal structure of carbonic anhydrase II in complex with a Nir inhibitor 分子名称: 3-(4-sulfamoylphenyl)-N-[6-({(6Z)-2-[(2Z)-2-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)ethyl]-6-[(2E)-2-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)ethylidene]cyclohex-1-en-1-yl}amino)hexyl]propanamide, Carbonic anhydrase 2, MERCURY (II) ION, ... 著者 Temperini, C, Cecchi, A. 登録日 2010-06-17 公開日 2011-06-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of carbonic anhydrase II in complex with a Nir inhibitor To be Published
1JBM	Heptameric crystal structure of Mth649, an Sm-like archaeal protein from Methanobacterium thermautotrophicum 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, PUTATIVE SNRNP SM-LIKE PROTEIN 著者 Mura, C, Eisenberg, D. 登録日 2001-06-06 公開日 2003-03-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs) Protein Sci., 12, 2003
4G7H	Crystal structure of Thermus thermophilus transcription initiation complex 分子名称: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2012-07-20 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of transcription initiation. Science, 338, 2012
3NKC	Crystal structure of AqpZ F43W,H174G,T183F 分子名称: Aquaporin Z, octyl beta-D-glucopyranoside 著者 Savage, D.F, O'Connell III, J.D, Finer-Moore, J, Stroud, R.M. 登録日 2010-06-18 公開日 2010-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural context shapes the aquaporin selectivity filter. Proc.Natl.Acad.Sci.USA, 107, 2010
1JCT	Glucarate Dehydratase, N341L mutant Orthorhombic Form 分子名称: D-GLUCARATE, Glucarate Dehydratase, ISOPROPYL ALCOHOL, ... 著者 Gulick, A.M, Hubbard, B.K, Gerlt, J.A, Rayment, I. 登録日 2001-06-11 公開日 2001-09-05 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli. Biochemistry, 40, 2001
6IBL	ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST FORMOTEROL AND NANOBODY Nb80 分子名称: Camelid antibody fragment Nb80, HEGA-10, SODIUM ION, ... 著者 Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G. 登録日 2018-11-30 公開日 2019-01-09 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular basis of beta-arrestin coupling to formoterol-bound beta1-adrenoceptor. Nature, 583, 2020
3U4D	Crystal structure of YwfH, NADPH dependent reductase involved in Bacilysin biosynthesis 分子名称: Bacilysin biosynthesis oxidoreductase ywfH 著者 Rajavel, M, Gopal, B. 登録日 2011-10-07 公開日 2013-03-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural insights into the role of Bacillus subtilis YwfH (BacG) in tetrahydrotyrosine synthesis Acta Crystallogr.,Sect.D, 69, 2013
6I2A	Crystal Structure of the Protein-Kinase A catalytic subunit from Cricetulus Griseus in complex with compounds RKp153 and Fasudil 分子名称: 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, UPF0418 protein FAM164A, beta-D-ribopyranose, ... 著者 Mueller, J.M, Heine, A, Klebe, G. 登録日 2018-11-01 公開日 2019-05-15 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019
3U4I	CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template 分子名称: ADP-ribosyl cyclase 1, Cyclic adenosine 5'-diphosphocarbocyclic ribose 著者 Liu, Q, Hao, Q, Lee, H.C, Graeff, R. 登録日 2011-10-08 公開日 2012-10-10 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.118 Å) 主引用文献 CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template Plos One, 8, 2013
4C4A	Crystal structure of mouse protein arginine methyltransferase 7 in complex with SAH 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, PROTEIN ARGININE N-METHYLTRANSFERASE 7, ... 著者 Cura, V, Troffer-Charlier, N, Bonnefond, L, Wurtz, J.M, Cavarelli, J. 登録日 2013-09-02 公開日 2014-07-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Insight Into Arginine Methylation by the Mouse Protein Arginine Methyltransferase 7: A Zinc Finger Freezes the Mimic of the Dimeric State Into a Single Active Site. Acta Crystallogr.,Sect.D, 70, 2014
3JRN	Crystal structure of TIR domain from Arabidopsis Thaliana 分子名称: ARSENIC, AT1G72930 protein 著者 Chan, S.L, Mukasa, T, Santelli, E, Low, L.Y, Pascual, J. 登録日 2009-09-08 公開日 2009-10-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure of a TIR domain from Arabidopsis thaliana reveals a conserved helical region unique to plants. Protein Sci., 19, 2009
2EU3	Human Carbonic anhydrase II in complex with novel inhibitors 分子名称: 1-(5-AMINO-1,3,4-THIADIAZOL-2-YL)-1,1-DIFLUOROMETHANESULFONAMIDE, Carbonic anhydrase 2, ZINC ION 著者 Fisher, S.Z, Govindasamy, L, Boyle, N, Agbandje-McKenna, M, Silverman, D.N, Blackburn, G.M, McKenna, R. 登録日 2005-10-28 公開日 2006-07-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes. Acta Crystallogr.,Sect.F, 62, 2006
3U5N	Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-20)K9me3K14ac histone peptide 分子名称: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION 著者 Wang, Z, Patel, D.J. 登録日 2011-10-11 公開日 2012-01-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A Poised Chromatin Platform for TGF-beta access to master regulators Cell(Cambridge,Mass.), 147, 2011
4FWJ	Native structure of LSD2/AOF1/KDM1b in spacegroup of I222 at 2.9A 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, PHOSPHATE ION, ... 著者 Zhang, Q, Chen, Z. 登録日 2012-07-01 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013

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