PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

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4NEJ	Small molecular fragment bound to crystal contact interface of Interleukin-2 分子名称: 5-methylfuran-2-carboxylic acid, Interleukin-2 著者 Brenke, R, Jehle, S, Vajda, S, Allen, K.N, Kozakov, D. 登録日 2013-10-29 公開日 2014-11-19 実験手法 X-RAY DIFFRACTION (1.919 Å) 主引用文献 Small molecular fragments bound to binding energy hot-spot in crystal contact interface of Interleukin-2 To be Published
5BOM	DNA polymerase beta binary complex with a templating 5ClC 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(4U3)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Freudenthal, B.D, Wilson, S.H. 登録日 2015-05-27 公開日 2015-08-19 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.0002 Å) 主引用文献 Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. Proc.Natl.Acad.Sci.USA, 112, 2015
5BOY	X-RAY Co-structure of MMP-13 with ethyl 5-(1-methyl-1H-imidazol-5-yl)-1H-indole-2-Carboxylate 分子名称: CALCIUM ION, Collagenase 3, ZINC ION, ... 著者 Farrow, N.A. 登録日 2015-05-27 公開日 2015-06-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Fragment-based discovery of indole inhibitors of matrix metalloproteinase-13. J. Med. Chem., 54, 2011
4RB3	Crystal structure of Magnetospirillum gryphiswaldense MSR-1 Fur-Mn2+-feoAB1 operator 分子名称: DNA (25-MER), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION, ... 著者 Deng, Z, Chen, Z. 登録日 2014-09-12 公開日 2015-07-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator. Nat Commun, 6
4NFG	K13R mutant of horse cytochrome c and yeast cytochrome c peroxidase complex 分子名称: Cytochrome c, Cytochrome c peroxidase, mitochondrial, ... 著者 Meulenbroek, E.M, Bashir, Q, Ubbink, M, Pannu, N.S. 登録日 2013-10-31 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Engineering specificity in a dynamic protein complex with a single conserved mutation. Febs J., 281, 2014
4NGE	Crystal Structure of Human Presequence Protease in Complex with Amyloid-beta (1-40) 分子名称: ACETATE ION, Beta-amyloid protein 40, GLYCEROL, ... 著者 King, J.V, Liang, W.G, Tang, W.J. 登録日 2013-11-01 公開日 2014-05-14 最終更新日 2014-07-23 実験手法 X-RAY DIFFRACTION (2.704 Å) 主引用文献 Molecular basis of substrate recognition and degradation by human presequence protease. Structure, 22, 2014
4NIX	Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) orthorhombic form, zinc-bound 分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ... 著者 Schoepfel, M, Parthier, C, Stubbs, M.T. 登録日 2013-11-08 公開日 2014-02-19 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 N-terminal protein modification by substrate-activated reverse proteolysis. Angew.Chem.Int.Ed.Engl., 53, 2014
6CUT	Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6 with (2S,3S)-isopropylserine bound as the external aldimine 分子名称: (2S,3S)-3-hydroxy-2-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-methylpentanoic acid (non-preferred name), SODIUM ION, Tryptophan synthase beta chain 1 著者 Boville, C.E, Scheele, R.A, Buller, A.R, Arnold, F.H. 登録日 2018-03-26 公開日 2018-09-26 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Engineered Biosynthesis of beta-Alkyl Tryptophan Analogues. Angew. Chem. Int. Ed. Engl., 57, 2018
5BRV	Catalytic Improvement of an Artificial Metalloenzyme by Computational Design 分子名称: Carbonic anhydrase 2, ZINC ION, pentamethylcyclopentadienyl iridium [N-benzensulfonamide-(2-pyridylmethyl-4-benzensulfonamide)amin] chloride 著者 Heinisch, T, Pellizzoni, M, Duerrenberger, M, Tinberg, C.E, Koehler, V, Klehr, J, Haeussinger, D, Baker, D, Ward, T.R. 登録日 2015-06-01 公開日 2015-06-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design. J.Am.Chem.Soc., 137, 2015
5VJE	Class II fructose-1,6-bisphosphate aldolase of Escherichia coli with D-glucitol 1,6-bisphosphate 分子名称: D-Glucitol-1,6-bisphosphate, Fructose-bisphosphate aldolase class 2, SODIUM ION 著者 Coincon, M, Sygusch, J. 登録日 2017-04-19 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases. J. Biol. Chem., 293, 2018
3U9H	Complex structure of human tankyrase 2 with nicotinamide 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, NICOTINAMIDE, ... 著者 Narwal, M, Lehtio, L. 登録日 2011-10-19 公開日 2011-11-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis of selective inhibition of human tankyrases. J.Med.Chem., 55, 2012
5W4U	Pol II elongation complex with an N6-methyladenine-containing template 分子名称: 14mer non-template DNA, 29mer template DNA, 9mer RNA, ... 著者 Wang, W, Wang, D. 登録日 2017-06-13 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing. J.Am.Chem.Soc., 139, 2017
5W6Q	Structural basis for recognition of artificial DNA by an evolved KlenTaq variant 分子名称: DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(1W5))-3'), DNA (5'-D(P*GP*(1WA)P*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA polymerase I, ... 著者 Singh, I, Georgiadis, M.M. 登録日 2017-06-16 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide. Nucleic Acids Res., 46, 2018
6CG0	Cryo-EM structure of mouse RAG1/2 HFC complex (3.17 A) 分子名称: CALCIUM ION, DNA (30-MER), DNA (41-MER), ... 著者 Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W. 登録日 2018-02-19 公開日 2018-04-25 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.17 Å) 主引用文献 Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
5YV1	DNA polymerase IV - DNA ternary complex 13 分子名称: DIPHOSPHATE, DNA polymerase IV, DTN1, ... 著者 Kottur, J, Nair, D.T. 登録日 2017-11-23 公開日 2018-09-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
5YW5	Crystal structure of Adenine phosphoribosyltransferase from Francisella tularensis in complex with adenine 分子名称: ADENINE, Adenine phosphoribosyltransferase 著者 Pavithra, G.C, Ramagopal, U.A. 登録日 2017-11-28 公開日 2018-01-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of APRT from Francisella tularensis - an N-H···N hydrogen bond imparts adenine specificity in adenine phosporibosyltransferases. FEBS J., 285, 2018
4NZ7	Steroid receptor RNA Activator (SRA) modification by the human Pseudouridine Synthase 1 (hPus1p): RNA binding, activity, and atomic model 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TRIETHYLENE GLYCOL, tRNA pseudouridine synthase A, ... 著者 Huet, T, Thore, S. 登録日 2013-12-11 公開日 2014-05-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Steroid Receptor RNA Activator (SRA) Modification by the Human Pseudouridine Synthase 1 (hPus1p): RNA Binding, Activity, and Atomic Model Plos One, 9, 2014
4QUO	Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-hPheP[CH2]Phe(3-CH2NH2) 分子名称: (2S)-2-[3-(aminomethyl)benzyl]-3-[(R)-[(1R)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]propanoic acid, Aminopeptidase N, GLYCEROL, ... 著者 Nocek, B, Mulligan, R, Joachimiak, A, Vassiliou, S, Berlicki, L, Mucha, A. 登録日 2014-07-11 公開日 2014-09-10 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J.Med.Chem., 57, 2014
4NQ0	Structural insights into yeast histone chaperone Hif1: a scaffold protein recruiting protein complexes to core histones 分子名称: HAT1-interacting factor 1 著者 Liu, H, Zhang, M, He, W, Zhu, Z, Teng, M, Gao, Y, Niu, L. 登録日 2013-11-23 公開日 2014-07-16 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights into yeast histone chaperone Hif1: a scaffold protein recruiting protein complexes to core histones Biochem.J., 462, 2014
5ALS	ligand complex structure of soluble epoxide hydrolase 分子名称: BIFUNCTIONAL EPOXIDE HYDROLASE 2, N-CYCLOPENTYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-3H-IMIDAZO[4,5-B]PYRIDINE-7-SULFONAMIDE, SULFATE ION 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-08 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
6D0A	Crystal structure of Kynurenine Aminotransferase-II in apo-form, at 1.47 A resolution 分子名称: Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 著者 Jayawickrama, G.S, Sun, G, Nematollahi, A, Church, W.B. 登録日 2018-04-10 公開日 2018-05-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.46809423 Å) 主引用文献 Crystal structure of Kynurenine Aminotransferase-II in apo-form To Be Published
5ZOC	Crystal structure of APRT from Y. pseudotuberculosis with bound adenine (C2 space group). 分子名称: ADENINE, Adenine phosphoribosyltransferase, SODIUM ION 著者 Pavithra, G.C, Ramagopal, U.A. 登録日 2018-04-12 公開日 2019-04-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal structure of APRT from Y. pseudotuberculosis with bound adenine (C2 space group). To be published
3TJG	Crystal Structure of human peroxiredoxin IV C51A mutant in oxidized form 分子名称: Peroxiredoxin-4 著者 Cao, Z, Tavender, T.J, Roszak, A.W, Cogdell, R.J, Bulleid, N.J. 登録日 2011-08-24 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle. J.Biol.Chem., 286, 2011
4KVJ	Crystal structure of Oryza sativa fatty acid alpha-dioxygenase with hydrogen peroxide 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G. 登録日 2013-05-22 公開日 2013-08-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Crystal structures of alpha-dioxygenase from Oryza sativa: Insights into substrate binding and activation by hydrogen peroxide. Protein Sci., 22, 2013
6CN7	The structure of aerobactin synthetase IucC from a hypervirulent pathotype of Klebsiella pneumoniae 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Aerobactin synthase IucC 著者 Bailey, D.C, Rice, M.R, Gulick, A.M. 登録日 2018-03-07 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural and functional delineation of aerobactin biosynthesis in hypervirulentKlebsiella pneumoniae. J. Biol. Chem., 293, 2018

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