2GKM
 
 | |
3RGD
 | | Iron loaded frog M ferritin. Short soaking time | | 分子名称: | FE (III) ION, Ferritin, middle subunit | | 著者 | Bertini, I, Lalli, D, Mangani, S, Pozzi, C, Rosa, C, Theil, E.C, Turano, P. | | 登録日 | 2011-04-08 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structural insights into the ferroxidase site of ferritins from higher eukaryotes.
J.Am.Chem.Soc., 134, 2012
|
|
5AN7
 | | Structure of the engineered retro-aldolase RA95.5-8F with a bound 1,3-diketone inhibitor | | 分子名称: | (2E)-1-(6-methoxynaphthalen-2-yl)but-2-en-1-one, PHOSPHATE ION, RA95.5-8F | | 著者 | Obexer, R, Mittl, P.R.E, Hilvert, D. | | 登録日 | 2015-09-04 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase.
Nat Chem, 9, 2017
|
|
3HCI
 | | Structure of MsrB from Xanthomonas campestris (complex-like form) | | 分子名称: | (2S)-2-(acetylamino)-N-methyl-4-[(R)-methylsulfinyl]butanamide, CALCIUM ION, Peptide methionine sulfoxide reductase, ... | | 著者 | Ranaivoson, F.M, Kauffmann, B, Favier, F. | | 登録日 | 2009-05-06 | | 公開日 | 2009-10-13 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Methionine sulfoxide reductase B displays a high level of flexibility.
J.Mol.Biol., 394, 2009
|
|
6VC9
 | | TB19 complex | | 分子名称: | 1,2-ETHANEDIOL, 5'-nucleotidase, ecto (CD73), ... | | 著者 | Zhou, Y.F, Lord, D.M. | | 登録日 | 2019-12-20 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms.
J.Biol.Chem., 295, 2020
|
|
4KNJ
 | | Crystal structure of human carbonic anhydrase isozyme II with 2-Chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide, Carbonic anhydrase 2, ... | | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | | 登録日 | 2013-05-10 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII
Bioorg.Med.Chem., 21, 2013
|
|
3RJK
 | | Ternary complex of DNA Polymerase Beta with a gapped DNA containing 8odG:dC base pair at primer terminus and dG:dCMP(CF2)PP in the active site | | 分子名称: | 2'-deoxy-5'-O-[(S)-{difluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]cytidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*GP*(8OG)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | | 著者 | Batra, V.K, Beard, W.A, Wilson, S.H. | | 登録日 | 2011-04-15 | | 公開日 | 2012-01-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Binary complex crystal structure of DNA polymerase beta reveals multiple conformations of the templating 8-oxoguanine lesion.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3HCJ
 | |
2C0D
 | | Structure of the mitochondrial 2-cys peroxiredoxin from Plasmodium falciparum | | 分子名称: | THIOREDOXIN PEROXIDASE 2 | | 著者 | Boucher, I.W, Brannigan, J.A, Wilkinson, A.J, Brzozowski, A.M, Muller, S. | | 登録日 | 2005-09-01 | | 公開日 | 2006-11-21 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural and Biochemical Characterisation of a Mitochondrial Peroxiredoxin from Plasmodium Falciparum
Mol.Microbiol., 61, 2006
|
|
6V9Y
 | | Structure of TRPA1 bound with A-967079, PMAL-C8 | | 分子名称: | Transient receptor potential cation channel subfamily A member 1 | | 著者 | Zhao, J, Lin King, J.V, Paulsen, C.E, Cheng, Y, Julius, D. | | 登録日 | 2019-12-16 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Irritant-evoked activation and calcium modulation of the TRPA1 receptor.
Nature, 585, 2020
|
|
6K7Y
 | | Intact human mitochondrial calcium uniporter complex with MICU1/MICU2 subunits | | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, CARDIOLIPIN, ... | | 著者 | Zhuo, W, Zhou, H, Yang, M. | | 登録日 | 2019-06-10 | | 公開日 | 2020-09-09 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of intact human MCU supercomplex with the auxiliary MICU subunits.
Protein Cell, 12, 2021
|
|
3RLD
 | |
6VBK
 | | Crystal structure of N-terminal domain of Mycobacterium tuberculosis complex Lon protease | | 分子名称: | GLYCEROL, Lon211 | | 著者 | Bi, F.K, Chen, C, Chen, X.Y, Guo, C.Y, Lin, D.H. | | 登録日 | 2019-12-19 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the N domain of Lon protease from Mycobacterium avium complex.
Protein Sci., 28, 2019
|
|
1BNT
 | | CARBONIC ANHYDRASE II INHIBITOR | | 分子名称: | 3,4-DIHYDRO-4-HYDROXY-2-(4-METHOXYPHENYL)-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, CARBONIC ANHYDRASE, MERCURY (II) ION, ... | | 著者 | Boriack-Sjodin, P.A, Zeitlin, S, Christianson, D.W. | | 登録日 | 1998-07-30 | | 公開日 | 1999-06-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
|
|
4KRD
 | | Crystal Structure of Pho85-Pcl10 Complex | | 分子名称: | Cyclin-dependent protein kinase PHO85, PHO85 cyclin-10 | | 著者 | Quiocho, F.A, Zheng, F. | | 登録日 | 2013-05-16 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | | 主引用文献 | New Structural Insights into Phosphorylation-free Mechanism for Full Cyclin-dependent Kinase (CDK)-Cyclin Activity and Substrate Recognition.
J.Biol.Chem., 288, 2013
|
|
3M1Q
 | |
1BIX
 | | THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES | | 分子名称: | AP ENDONUCLEASE 1, PLATINUM (II) ION, SAMARIUM (III) ION | | 著者 | Gorman, M.A, Morera, S, Rothwell, D.G, De La Fortelle, E, Mol, C.D, Tainer, J.A, Hickson, I.D, Freemont, P.S. | | 登録日 | 1998-06-19 | | 公開日 | 1999-06-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.
EMBO J., 16, 1997
|
|
3B1T
 | | Crystal structure of human peptidylarginine deiminase 4 in complex with o-Cl-amidine | | 分子名称: | 2-{[(2S)-1-amino-5-{[(1Z)-2-chloroethanimidoyl]amino}-1-oxopentan-2-yl]carbamoyl}benzoic acid, CALCIUM ION, Protein-arginine deiminase type-4, ... | | 著者 | Causey, C.P, Jones, J.E, Slack, J.L, Kamei, D, Jones Jr, L.E, Subramanian, V, Knuckley, B, Ebrahimi, P, Chumanevich, A.A, Luo, Y, Hashimoto, H, Shimizu, T, Sato, M, Hofseth, L.J, Thompson, P.R. | | 登録日 | 2011-07-13 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Development of N-alpha-(2-Carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine Amide (o-F-amidine) and N-alpha-(2-Carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine Amide (o-Cl-amidine) As Second Generation Protein Arginine Deiminase (PAD) Inhibitors
J.Med.Chem., 54, 2011
|
|
5C3E
 | | Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G. | | 登録日 | 2015-06-17 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
|
|
3M2N
 | | Crystal structure of human carbonic anhydrase isozyme II with 4-{2-[N-(6-chloro-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide | | 分子名称: | 4-{2-[(6-chloro-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... | | 著者 | Grazulis, S, Manakova, E, Golovenko, D. | | 登録日 | 2010-03-08 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases.
Eur.J.Med.Chem., 51, 2012
|
|
1YZ1
 | |
3M2Z
 | |
2H71
 | |
1C3S
 | |
6JZV
 | |
