3TO7
 
 | Crystal structure of yeast Esa1 HAT domain bound to coenzyme A with active site lysine acetylated | 分子名称: | CACODYLIC ACID, COENZYME A, GLYCEROL, ... | 著者 | Yuan, H, Ding, E.C, Marmorstein, R. | 登録日 | 2011-09-04 | 公開日 | 2011-11-09 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
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3M31
 
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1BIC
 
 | CRYSTALLOGRAPHIC ANALYSIS OF THR-200-> HIS HUMAN CARBONIC ANHYDRASE II AND ITS COMPLEX WITH THE SUBSTRATE, HCO3- | 分子名称: | BICARBONATE ION, CARBONIC ANHYDRASE II, METHYL MERCURY ION, ... | 著者 | Xue, Y, Vidgren, J, Svensson, L.A, Liljas, A, Jonsson, B.-H, Lindskog, S. | 登録日 | 1992-09-01 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystallographic analysis of Thr-200-->His human carbonic anhydrase II and its complex with the substrate, HCO3-. Proteins, 15, 1993
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3LZX
 
 | Crystal structure of ferredoxin-NADP+ oxidoreductase from Bacillus subtilis (FORM II) | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Komori, H, Seo, D, Sakurai, T, Higuchi, Y. | 登録日 | 2010-03-02 | 公開日 | 2010-12-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure analysis of Bacillus subtilis ferredoxin-NADP(+) oxidoreductase and the structural basis for its substrate selectivity Protein Sci., 19, 2010
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8EIT
 
 | Structure of FFAR1-Gq complex bound to DHA | 分子名称: | A modified Guanine nucleotide-binding protein G(q) subunit alpha, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 1, ... | 著者 | Kumari, P, Inoue, A, Chapman, K, Lian, P, Rosenbaum, D.M. | 登録日 | 2022-09-15 | 公開日 | 2023-05-24 | 最終更新日 | 2025-05-28 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Molecular mechanism of fatty acid activation of FFAR1. Proc.Natl.Acad.Sci.USA, 120, 2023
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3BZK
 
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3U47
 
 | Human Carbonic Anhydrase II V143L | 分子名称: | Carbonic anhydrase 2, GLYCEROL, ZINC ION | 著者 | West, D, Mckenna, R. | 登録日 | 2011-10-07 | 公開日 | 2012-10-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural modification of the hydrophobic pocket of Human Carbonic Anhydrase II To be Published
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8EJK
 
 | Structure of FFAR1-Gq complex bound to TAK-875 in a lipid nanodisc | 分子名称: | A modified Guanine nucleotide-binding protein G(q) subunit alpha, Free fatty acid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Kumari, P, Inoue, A, Chapman, K, Lian, P, Rosenbaum, D.M. | 登録日 | 2022-09-17 | 公開日 | 2023-05-24 | 最終更新日 | 2024-10-30 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular mechanism of fatty acid activation of FFAR1. Proc.Natl.Acad.Sci.USA, 120, 2023
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3U4C
 
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8EJC
 
 | Structure of FFAR1-Gq complex bound to TAK-875 | 分子名称: | A modified Guanine nucleotide-binding protein G(q) subunit alpha, Free fatty acid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Kumari, P, Inoue, A, Chapman, K, Lian, P, Rosenbaum, D.M. | 登録日 | 2022-09-16 | 公開日 | 2023-05-24 | 最終更新日 | 2024-10-30 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular mechanism of fatty acid activation of FFAR1. Proc.Natl.Acad.Sci.USA, 120, 2023
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3U4H
 
 | CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template | 分子名称: | 8-Amino-N1-Cyclic Inosine 5'-Diphosphoribose, ADP-ribosyl cyclase 1 | 著者 | Liu, Q, Hao, Q, Lee, H.C, Graeff, R. | 登録日 | 2011-10-08 | 公開日 | 2012-10-10 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (1.878 Å) | 主引用文献 | CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template Plos One, 8, 2013
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2GB1
 
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3GSY
 
 | Structure of berberine bridge enzyme in complex with dehydroscoulerine | 分子名称: | 2,9-dihydroxy-3,10-dimethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium, 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Winkler, A, Macheroux, P, Gruber, K. | 登録日 | 2009-03-27 | 公開日 | 2009-06-30 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Berberine bridge enzyme catalyzes the six electron oxidation of (S)-reticuline to dehydroscoulerine. Phytochemistry, 70, 2009
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8FOB
 
 | Cryo-EM structure of human TRPV6 in the open state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, ... | 著者 | Neuberger, A, Yelshanskaya, M.V, Nadezhdin, K.D, Sobolevsky, A.I. | 登録日 | 2022-12-30 | 公開日 | 2023-05-24 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein. Nat Commun, 14, 2023
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3GTO
 
 | Backtracked RNA polymerase II complex with 15mer RNA | 分子名称: | DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D. | 登録日 | 2009-03-27 | 公開日 | 2009-06-09 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution. Science, 324, 2009
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1PU9
 
 | Crystal Structure of Tetrahymena GCN5 with Bound Coenzyme A and a 19-residue Histone H3 Peptide | 分子名称: | COENZYME A, HAT A1, Histone H3 | 著者 | Clements, A, Poux, A.N, Lo, W.S, Pillus, L, Berger, S.L, Marmorstein, R. | 登録日 | 2003-06-24 | 公開日 | 2003-09-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for histone and phospho-histone binding by the GCN5 histone acetyltransferase Mol.Cell, 12, 2003
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1PW6
 
 | Low Micromolar Small Molecule Inhibitor of IL-2 | 分子名称: | 2-CYCLOHEXYL-N-(2-{4-[5-(2,3-DICHLORO-PHENYL)-2H-PYRAZOL-3-YL]-PIPERIDIN-1-YL}-2-OXO-ETHYL)-2-GUANIDINO-ACETAMIDE, Interleukin-2, SULFATE ION | 著者 | Thanos, C.D, Randal, M, Wells, J.A. | 登録日 | 2003-06-30 | 公開日 | 2004-01-13 | 最終更新日 | 2024-11-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Potent small-molecule binding to a dynamic hot spot on IL-2. J.Am.Chem.Soc., 125, 2003
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3TJL
 
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3M98
 
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6JWP
 
 | crystal structure of EGOC | 分子名称: | Ego2, GTP-binding protein GTR1, GTP-binding protein GTR2, ... | 著者 | Zhang, T, Ding, J. | 登録日 | 2019-04-21 | 公開日 | 2019-12-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into the EGO-TC-mediated membrane tethering of the TORC1-regulatory Rag GTPases. Sci Adv, 5, 2019
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3U2C
 
 | Aldose reductase in complex with NSAID-type inhibitor at 1.0 A resolution | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Aldose reductase, CITRIC ACID, ... | 著者 | Steuber, H. | 登録日 | 2011-10-03 | 公開日 | 2011-11-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | An old NSAID revisited: crystal structure of aldose reductase in complex with sulindac at 1.0 A supports a novel mechanism for its anticancer and antiproliferative effects. Chemmedchem, 6, 2011
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5A7Y
 
 | Crystal structure of Sulfolobus acidocaldarius Trm10 in complex with S-adenosylhomocysteine | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Van Laer, B, Roovers, M, Wauters, L, Kasprzak, J, Dyzma, M, Deyaert, E, Feller, A, Bujnicki, J, Droogmans, L, Versees, W. | 登録日 | 2015-07-10 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue. Nucleic Acids Res., 44, 2016
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2BJY
 
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3GYP
 
 | Rtt106p | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Histone chaperone RTT106 | 著者 | Liu, Y, Huang, H, Shi, Y, Teng, M. | 登録日 | 2009-04-04 | 公開日 | 2009-12-08 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.406 Å) | 主引用文献 | Structural analysis of Rtt106p reveals a DNA-binding role required for heterochromatin silencing J.Biol.Chem., 285, 2010
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3RG3
 
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