PDB: 1955 件ウェブページステータス検索Chemie searchBIRD

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4ADP	HCV-J6 NS5B POLYMERASE V405I MUTANT 分子名称: RNA-DIRECTED RNA POLYMERASE 著者 Scrima, N, Bressanelli, S. 登録日 2012-01-02 公開日 2012-05-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405. J.Virol., 86, 2012
2XHU	HCV-J4 NS5B Polymerase Orthorhombic Crystal Form 分子名称: RNA-directed RNA polymerase, SULFATE ION 著者 Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. 登録日 2010-06-21 公開日 2010-08-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.287 Å) 主引用文献 Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
2XHW	HCV-J4 NS5B Polymerase Trigonal Crystal Form 分子名称: RNA-directed RNA polymerase 著者 Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. 登録日 2010-06-21 公開日 2010-08-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
2YIB	Structure of the RNA polymerase VP1 from Infectious Pancreatic Necrosis Virus 分子名称: RNA-DIRECTED RNA POLYMERASE 著者 Graham, S.C, Sarin, L.P, Bahar, M.W, Myers, R.A, Stuart, D.I, Bamford, D.H, Grimes, J.M. 登録日 2011-05-11 公開日 2011-07-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 The N-Terminus of the RNA Polymerase from Infectious Pancreatic Necrosis Virus is the Determinant of Genome Attachment. Plos Pathog., 7, 2011
2HCS	Crystal structure of RNA dependant RNA polymerase domain of West Nile virus 分子名称: RNA-directed RNA polymerase (NS5), ZINC ION 著者 Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP) 登録日 2006-06-18 公開日 2007-02-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5 J.Biol.Chem., 282, 2007
7VH3	Cryo-EM structure of Machupo virus polymerase L 分子名称: RNA-directed RNA polymerase L 著者 Ma, J, Zhang, S, Zhang, X. 登録日 2021-09-20 公開日 2021-09-29 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
7VH2	Cryo-EM structure of Machupo virus dimeric polymerase L 分子名称: RNA-directed RNA polymerase L 著者 Zhang, X, Ma, J, Zhang, S. 登録日 2021-09-20 公開日 2021-09-29 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
8K43	In situ structure of RNA-dependent RNA polymerase in full BAV particles 分子名称: RNA-directed RNA polymerase (Fragment), VP2 著者 Li, Z, Cao, S. 登録日 2023-07-17 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM structures of Banna virus in multiple states reveal stepwise detachment of viral spikes. Nat Commun, 15, 2024
4ZP8	Coxsackievirus B3 Polymerase - F364L mutant 分子名称: RNA-dependent RNA polymerase 著者 Peersen, O.B, McDonald, S.M. 登録日 2015-05-07 公開日 2016-05-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.894 Å) 主引用文献 Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
4ZP9	Coxsackievirus B3 Polymerase - F364I mutant 分子名称: RNA-dependent RNA polymerase 著者 Peersen, O.B, McDonald, S.M. 登録日 2015-05-07 公開日 2016-05-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
4ZPC	Coxsackievirus B3 Polymerase - A341G mutant 分子名称: RNA-dependent RNA polymerase 著者 Peersen, O.B, McDonald, S.M. 登録日 2015-05-07 公開日 2016-05-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
5Y3D	Structural insight into the interaction between RNA polymerase and VPg for norovirus replication 分子名称: RNA-dependent RNA polymerase, viral protein genome-linked (VPg) 著者 Kim, K.H, Lee, J.-H, Seok, J.H. 登録日 2017-07-28 公開日 2018-07-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication. Front Microbiol, 9, 2018
4K4Z	Coxsackievirus B3 polymerase elongation complex (r2_Mg_form) 分子名称: MAGNESIUM ION, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*A)-3'), ... 著者 Gong, P, Peersen, O.B. 登録日 2013-04-12 公開日 2013-05-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One, 8, 2013
4K4X	Coxsackievirus B3 polymerase elongation complex (r2_form), rna 分子名称: GLYCEROL, MAGNESIUM ION, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), ... 著者 Gong, P, Peersen, O.B. 登録日 2013-04-12 公開日 2013-05-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One, 8, 2013
4K4Y	Coxsackievirus B3 polymerase elongation complex (r2+1_form) 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ACETATE ION, DNA/RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*(DOC))-3'), ... 著者 Gong, P, Peersen, O.B. 登録日 2013-04-12 公開日 2013-05-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One, 8, 2013
3JA5	Genome and RdRp structure within the capsid of no-transcribing cypovirus 分子名称: RNA-dependent RNA polymerase 著者 Liu, H, Cheng, L. 登録日 2015-04-21 公開日 2015-10-28 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (12 Å) 主引用文献 Cryo-EM shows the polymerase structures and a nonspooled genome within a dsRNA virus. Science, 349, 2015
7OM9	Thosea asigna virus RdRP domain 分子名称: RNA-dependent RNA polymerase 著者 Ferrero, D.S, Falqui, M, Verdaguer, N. 登録日 2021-05-21 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021
6K32	RdRp complex 分子名称: 2'-O-methyladenosine 5'-(dihydrogen phosphate), 7-METHYLGUANOSINE, DIPHOSPHATE, ... 著者 Li, X.W. 登録日 2019-05-16 公開日 2019-11-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of RdRps Within a Transcribing dsRNA Virus Provides Insights Into the Mechanisms of RNA Synthesis. J.Mol.Biol., 432, 2020
6XEZ	Structure of SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... 著者 Chen, J, Malone, B, Llewellyn, E.C, Campbell, E.A, Darst, S.A. 登録日 2020-06-14 公開日 2020-07-29 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex. Cell, 182, 2020
7OCH	Apo-structure of Lassa virus L protein (well-resolved polymerase core) [APO-CORE] 分子名称: MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION 著者 Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. 登録日 2021-04-26 公開日 2021-12-01 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
7OEA	Lassa virus L protein bound to 3' promoter RNA (well-resolved polymerase core) [3END-CORE] 分子名称: 3' vRNA, MAGNESIUM ION, RNA-directed RNA polymerase L, ... 著者 Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. 登録日 2021-05-02 公開日 2021-12-01 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
4NLV	Poliovirus Polymerase - G289A/C290F Loop Mutant 分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... 著者 Sholders, A.J, Peersen, O.B. 登録日 2013-11-14 公開日 2014-01-22 最終更新日 2014-03-26 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
7OJK	Lassa virus L protein bound to the distal promoter duplex [DISTAL-PROMOTER] 分子名称: 3' RNA, 5' RNA, RNA-directed RNA polymerase L, ... 著者 Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. 登録日 2021-05-16 公開日 2021-12-01 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.89 Å) 主引用文献 Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
7OJN	Lassa virus L protein in an elongation conformation [ELONGATION] 分子名称: 3' RNA, 5' RNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... 著者 Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. 登録日 2021-05-16 公開日 2021-12-01 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
7OJL	Lassa virus L protein in a pre-initiation conformation [PREINITIATION] 分子名称: 3' RNA, 5' RNA, MANGANESE (II) ION, ... 著者 Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. 登録日 2021-05-16 公開日 2021-12-01 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021

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