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4I70

Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase

Summary for 4I70
Entry DOI10.2210/pdb4i70/pdb
Related4I71 4I72 4I73 4I74 4I75
DescriptorInosine-adenosine-guanosine-nucleoside hydrolase, CALCIUM ION (3 entities in total)
Functional Keywordsnucleoside hydrolase, open (alpha, beta) structure, nh fold, nucleotide metabolism, hydrolase
Biological sourceTrypanosoma brucei brucei
Total number of polymer chains1
Total formula weight35925.38
Authors
Giannese, F.,Degano, M. (deposition date: 2012-11-30, release date: 2013-08-07, Last modification date: 2024-04-03)
Primary citationGiannese, F.,Berg, M.,Van der Veken, P.,Castagna, V.,Tornaghi, P.,Augustyns, K.,Degano, M.
Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor
Acta Crystallogr.,Sect.D, 69:1553-1566, 2013
Cited by
PubMed: 23897478
DOI: 10.1107/S0907444913010792
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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