PDB: 608 件ウェブページステータス検索Chemie searchBIRD

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8C28	14-3-3 in complex with PyrinpS208pS242 分子名称: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pyrin 著者 Lau, R, Ottmann, C, Hann, M. 登録日 2022-12-21 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 14-3-3/Pyrin complex To Be Published
8C30	Crystal structure of 14-3-3 in complex with PyrinpS242 and a protein/peptide interface fragment 分子名称: 14-3-3 protein sigma, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, ... 著者 Lau, R, Ottmann, C. 登録日 2022-12-23 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 14-3-3/Pyrin complex To Be Published
5MHC	Crystal structure of 14-3-3sigma and a p53 C-terminal 12-mer synthetic phosphopeptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, LYS-LEU-MET-PHE-LYS-TPO-GLU-GLY-PRO-ASP-SER-ASP, ... 著者 Andrei, S, Ottmann, C, Leysen, S. 登録日 2016-11-24 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction. FEBS Lett., 591, 2017
5MYC	Crystal structure of human 14-3-3 sigma in complex with LRRK2 peptide pS910 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Stevers, L.M, de Vries, R.M.J.M, Ottmann, C. 登録日 2017-01-26 公開日 2017-03-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.459 Å) 主引用文献 Structural interface between LRRK2 and 14-3-3 protein. Biochem. J., 474, 2017
5MXO	Crystal structure of 14-3-3sigma and a p53 C-terminal 12-mer synthetic phosphopeptide stabilized by Fusicoccin-A 分子名称: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... 著者 Andrei, S, Ottmann, C, Leysen, S. 登録日 2017-01-24 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction. FEBS Lett., 591, 2017
5MOC	Crystal structure of 14-3-3sigma and a p53 C-terminal 12-mer synthetic phosphopeptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... 著者 Andrei, S, Ottmann, C, Leysen, S. 登録日 2016-12-14 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction. FEBS Lett., 591, 2017
5MY9	Crystal structure of human 14-3-3 sigma in complex with LRRK2 peptide pS935 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Stevers, L.M, de Vries, R.M.J.M, Ottmann, C. 登録日 2017-01-26 公開日 2017-03-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.327 Å) 主引用文献 Structural interface between LRRK2 and 14-3-3 protein. Biochem. J., 474, 2017
5N5T	14-3-3 sigma in complex with TAZ pS89 peptide and fragment NV2 分子名称: 14-3-3 protein sigma, 4-[3,5-bis(chloranyl)pyridin-2-yl]oxyphenol, CHLORIDE ION, ... 著者 Sijbesma, E, Leysen, S, Ottmann, C. 登録日 2017-02-14 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Identification of Two Secondary Ligand Binding Sites in 14-3-3 Proteins Using Fragment Screening. Biochemistry, 56, 2017
5N10	Cucurbit[8]uril and 14-3-3 based binary bivalent supramolecular-protein assembly platform 分子名称: 14-3-3 protein beta/alpha, Cucurbit[8]uril, Estrogen receptor, ... 著者 de Vink, P.J, Ottmann, C. 登録日 2017-02-04 公開日 2017-05-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3. Angew. Chem. Int. Ed. Engl., 56, 2017
5N5W	14-3-3 sigma in complex with TAZ pS89 peptide and fragment NV3 分子名称: 14-3-3 protein sigma, 4-[3,5-bis(chloranyl)pyridin-2-yl]oxyaniline, CALCIUM ION, ... 著者 Sijbesma, E, Leysen, S, Ottmann, C. 登録日 2017-02-14 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Identification of Two Secondary Ligand Binding Sites in 14-3-3 Proteins Using Fragment Screening. Biochemistry, 56, 2017
5N75	14-3-3 sigma in complex with TAZ pS89 peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... 著者 Sijbesma, E, Leysen, S, Ottmann, C. 登録日 2017-02-19 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Identification of Two Secondary Ligand Binding Sites in 14-3-3 Proteins Using Fragment Screening. Biochemistry, 56, 2017
5N5R	14-3-3 sigma in complex with TAZ pS89 peptide and fragment NV1 分子名称: 14-3-3 protein sigma, 2-azanyl-~{N}-(2,6-dimethylphenyl)-~{N}-propan-2-yl-ethanamide, CHLORIDE ION, ... 著者 Sijbesma, E, Leysen, S, Ottmann, C. 登録日 2017-02-14 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Identification of Two Secondary Ligand Binding Sites in 14-3-3 Proteins Using Fragment Screening. Biochemistry, 56, 2017
5M37	The molecular tweezer CLR01 stabilizes a disordered protein-protein interface 分子名称: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein zeta/delta, BENZOIC ACID, ... 著者 Bier, D, Ottmann, C. 登録日 2016-10-14 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface. J. Am. Chem. Soc., 139, 2017
5LVZ	Crystal structure of yeast 14-3-3 protein from Lachancea thermotolerans 分子名称: KLTH0G14146p 著者 Klima, M, Boura, E. 登録日 2016-09-14 公開日 2016-10-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structures of a yeast 14-3-3 protein from Lachancea thermotolerans in the unliganded form and bound to a human lipid kinase PI4KB-derived peptide reveal high evolutionary conservation. Acta Crystallogr.,Sect.F, 72, 2016
5OEG	Molecular tweezers modulate 14-3-3 protein-protein interactions 分子名称: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein sigma, CHLORIDE ION 著者 Bier, D, Ottmann, C. 登録日 2017-07-07 公開日 2017-07-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Molecular tweezers modulate 14-3-3 protein-protein interactions. Nat Chem, 5, 2013
5NWK	14-3-3c in complex with CPP and fusicoccin 分子名称: 14-3-3 c-1 protein, FUSICOCCIN, PHOSPHOSERINE, ... 著者 Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. 登録日 2017-05-06 公開日 2017-11-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell, 29, 2017
5NAS	Crystal structure of human 14-3-3 zeta in complex with PI4KIIIB peptide 分子名称: 14-3-3 protein zeta/delta, Phosphatidylinositol 4-kinase beta 著者 Boura, E, Eisenreichova, A. 登録日 2017-02-28 公開日 2017-03-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Crystal structure of human 14-3-3 zeta in complex with PI4KIIIB peptide To Be Published
5NWI	14-3-3c in complex with CPP 分子名称: 14-3-3 c-1 protein, ACETATE ION, Potassium channel KAT1 著者 Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. 登録日 2017-05-06 公開日 2017-11-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell, 29, 2017
5NWJ	14-3-3c in complex with CPP7 分子名称: 14-3-3-like protein C, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. 登録日 2017-05-06 公開日 2017-11-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell, 29, 2017
5OK9	CH1 chimera of human 14-3-3 sigma with the HSPB6 phosphopeptide in a conformation with swapped phosphopeptides 分子名称: 14-3-3 protein sigma,Heat shock protein beta-6, DI(HYDROXYETHYL)ETHER 著者 Sluchanko, N.N, Tugaeva, K.V, Greive, S.J, Antson, A.A. 登録日 2017-07-25 公開日 2017-10-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners. Sci Rep, 7, 2017
5OEH	Molecular tweezers modulate 14-3-3 protein-protein interactions. 分子名称: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Bier, D, Ottmann, C. 登録日 2017-07-07 公開日 2017-07-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Molecular tweezers modulate 14-3-3 protein-protein interactions. Nat Chem, 5, 2013
5OKF	CH1 chimera of human 14-3-3 sigma with the HSPB6 phosphopeptide in a conformation with self-bound phosphopeptides 分子名称: 14-3-3 protein sigma,Heat shock protein beta-6, CADMIUM ION 著者 Sluchanko, N.N, Tugaeva, K.V, Greive, S.J, Antson, A.A. 登録日 2017-07-25 公開日 2017-10-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners. Sci Rep, 7, 2017
7OBC	Crystal structure of 14-3-3 sigma in complex with Phosphorylated and Farnesylated Rnd3 peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, FARNESYL, ... 著者 Centorrino, F, Andlovic, B, Ottmann, C. 登録日 2021-04-21 公開日 2022-05-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OB8	Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide and stabilizer Fusicoccin-A 分子名称: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... 著者 Centorrino, F, Andlovic, B, Ottmann, C. 登録日 2021-04-21 公開日 2022-05-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OB5	Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Centorrino, F, Andlovic, B, Ottmann, C. 登録日 2021-04-21 公開日 2022-05-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

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