8BZE

FC-J stabilizer for ERa and 14-3-3

Summary for 8BZE

• Entry DOI: 10.2210/pdb8bze/pdb
• Descriptor: 14-3-3 protein sigma, ERalpha peptide, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: 14-3-3, stabilization, eralpha, fc-j, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 27810.18

Authors

Visser, E.J.,Ottmann, C. (deposition date: 2022-12-14, release date: 2024-06-26, Last modification date: 2024-11-13)

• Primary citation: Visser, E.J.,Donaldson Collier, M.,Siefert, J.,Konstantinidou, M.,Paul, S.,Cossar, P.,Miley, G.,Meijer, O.,Arkin, M.R.,Ottmann, C.,Zwart, W.,Brunsveld, L.; Stabilization of the Estrogen receptor alpha - 14-3-3 interaction as a new potential intervention strategy for endocrine resistance in breast cancer; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.43 Å)