5MOC

Crystal structure of 14-3-3sigma and a p53 C-terminal 12-mer synthetic phosphopeptide

Summary for 5MOC

Entry DOI	10.2210/pdb5moc/pdb
Descriptor	14-3-3 protein sigma, p53 C-terminal domain, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	14-3-3 p53 c-terminus, antitumor protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	28052.19
Authors	Andrei, S.,Ottmann, C.,Leysen, S. (deposition date: 2016-12-14, release date: 2017-10-04, Last modification date: 2024-01-17)
Primary citation	Doveston, R.G.,Kuusk, A.,Andrei, S.A.,Leysen, S.,Cao, Q.,Castaldi, M.P.,Hendricks, A.,Brunsveld, L.,Chen, H.,Boyd, H.,Ottmann, C. Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction. FEBS Lett., 591:2449-2457, 2017 Cited by PubMed: 28640363 DOI: 10.1002/1873-3468.12723 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation