6D6I
| Ube2V1 in complex with ubiquitin variant Ubv.V1.1 and Ube2N/Ubc13 | 分子名称: | Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 1, Ubv.V1.1 | 著者 | Ceccarelli, D.F, Garg, P, Keszei, A, Sidhu, S, Sicheri, F. | 登録日 | 2018-04-21 | 公開日 | 2019-07-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.551 Å) | 主引用文献 | Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes. J.Mol.Biol., 432, 2020
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6JB7
| Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.1 A resolution | 分子名称: | Ubiquitin, Ubiquitin-conjugating enzyme E2 K | 著者 | Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Mun, S.A, Park, J, Park, T, Jin, M.W, Yang, J, Eom, S.H. | 登録日 | 2019-01-25 | 公開日 | 2019-03-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.1 A resolution To Be Published
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2Y9M
| Pex4p-Pex22p structure | 分子名称: | 1,2-ETHANEDIOL, PEROXISOME ASSEMBLY PROTEIN 22, UBIQUITIN-CONJUGATING ENZYME E2-21 KDA | 著者 | Williams, C, van den Berg, M, Panjikar, S, Distel, B, Wilmanns, M. | 登録日 | 2011-02-15 | 公開日 | 2011-10-26 | 最終更新日 | 2017-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Insights Into Ubiquitin-Conjugating Enzyme/ Co-Activator Interactions from the Structure of the Pex4P:Pex22P Complex. Embo J., 31, 2011
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1TTE
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1UR6
| NMR based structural model of the UbcH5B-CNOT4 complex | 分子名称: | POTENTIAL TRANSCRIPTIONAL REPRESSOR NOT4HP, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA 2, ZINC ION | 著者 | Dominguez, C, Bonvin, A.M.J.J, Winkler, G.S, Van Schaik, F.M.A, Timmers, H.Th.M, Boelens, R. | 登録日 | 2003-10-27 | 公開日 | 2004-05-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR, THEORETICAL MODEL | 主引用文献 | Structural Model of the Ubch5B/Cnot4 Complex Revealed by Combining NMR, Mutagenesis, and Docking Approaches. Structure, 12, 2004
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3FN1
| E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. | 分子名称: | NEDD8-activating enzyme E1 catalytic subunit, NEDD8-conjugating enzyme UBE2F | 著者 | Huang, D.T, Ayrault, O, Hunt, H.W, Taherbhoy, A.M, Duda, D.M, Scott, D.C, Borg, L.A, Neale, G, Murray, P.J, Roussel, M.F, Schulman, B.A. | 登録日 | 2008-12-22 | 公開日 | 2009-03-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification Mol.Cell, 33, 2009
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3SY2
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3RCZ
| Rad60 SLD2 Ubc9 Complex | 分子名称: | DNA repair protein rad60, SUMO-conjugating enzyme ubc9 | 著者 | Perry, J.J.P, Arvai, A.S, Tainer, J.A. | 登録日 | 2011-03-31 | 公開日 | 2011-04-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes. Mol.Cell.Biol., 31, 2011
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8EAZ
| HOIL-1/E2-Ub/Ub transthiolation complex | 分子名称: | RanBP-type and C3HC4-type zinc finger-containing protein 1, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... | 著者 | Wang, X.S, Cotton, T.R, Lechtenberg, B.C. | 登録日 | 2022-08-30 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family. Nat Commun, 14, 2023
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8EB0
| RNF216/E2-Ub/Ub transthiolation complex | 分子名称: | E3 ubiquitin-protein ligase RNF216, SULFATE ION, Ubiquitin, ... | 著者 | Cotton, T.R, Wang, X.S, Lechtenberg, B.C. | 登録日 | 2022-08-30 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family. Nat Commun, 14, 2023
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6SQO
| Crystal structure of human MDM2 RING domain homodimer bound to UbcH5B-Ub | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | 著者 | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | 登録日 | 2019-09-04 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
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8E2D
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8E2G
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8E2E
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8E2I
| Cryo-EM structure of BIRC6/Smac | 分子名称: | Baculoviral IAP repeat-containing protein 6, Diablo IAP-binding mitochondrial protein | 著者 | Hunkeler, M, Fischer, E.S. | 登録日 | 2022-08-15 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases. Science, 379, 2023
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8E2F
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8E2K
| Cryo-EM structure of BIRC6/HtrA2-S306A | 分子名称: | Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial | 著者 | Hunkeler, M, Fischer, E.S. | 登録日 | 2022-08-15 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases. Science, 379, 2023
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8E2H
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3FSH
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4MDK
| Cdc34-ubiquitin-CC0651 complex | 分子名称: | 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid, Ubiquitin, Ubiquitin-conjugating enzyme E2 R1 | 著者 | Ceccarelli, D.F, Orlicky, S, Tyers, M, Sicheri, F. | 登録日 | 2013-08-22 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6095 Å) | 主引用文献 | E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin. Nat.Chem.Biol., 10, 2014
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4LDT
| The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin, ... | 著者 | Wiener, R, DiBello, A.T, Lombardi, P.M, Guzzo, C.M, Zhang, X, Matunis, M.J, Wolberger, C. | 登録日 | 2013-06-25 | 公開日 | 2013-08-14 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1. Nat.Struct.Mol.Biol., 20, 2013
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3UIP
| Complex between human RanGAP1-SUMO1, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II | 分子名称: | E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... | 著者 | Gareau, J.R, Reverter, D, Lima, C.D. | 登録日 | 2011-11-05 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.293 Å) | 主引用文献 | Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
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3SQV
| Crystal Structure of E. coli O157:H7 E3 ubiquitin ligase, NleL, with a human E2, UbcH7 | 分子名称: | GLYCEROL, SULFATE ION, Ubiquitin-conjugating enzyme E2 L3, ... | 著者 | Lin, D.Y, Chen, J. | 登録日 | 2011-07-06 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions. Proc.Natl.Acad.Sci.USA, 109, 2012
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4LAD
| Crystal Structure of the Ube2g2:RING-G2BR complex | 分子名称: | E3 ubiquitin-protein ligase AMFR, OXALATE ION, Ubiquitin-conjugating enzyme E2 G2, ... | 著者 | Liang, Y.-H, Li, J, Das, R, Byrd, R.A, Ji, X. | 登録日 | 2013-06-19 | 公開日 | 2013-08-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine. Embo J., 32, 2013
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3E46
| Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington interacting protein 2) M172A mutant | 分子名称: | CALCIUM ION, Ubiquitin-conjugating enzyme E2-25 kDa | 著者 | Hughes, R.C, Wilson, R.C, Flatt, J.W, Meehan, E.J, Ng, J.D, Twigg, P.D. | 登録日 | 2008-08-09 | 公開日 | 2008-08-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2). Acta Crystallogr.,Sect.F, 65, 2009
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