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6D4P
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BU of 6d4p by Molmil
Ube2D1 in complex with ubiquitin variant Ubv.D1.1
分子名称: Ubiquitin Variant Ubv.D1.1, Ubiquitin-conjugating enzyme E2 D1
著者Ceccarelli, D.F, Garg, P, Sidhu, S, Sicheri, F.
登録日2018-04-18
公開日2019-07-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes.
J.Mol.Biol., 432, 2020
6D68
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BU of 6d68 by Molmil
Ube2G1 in complex with ubiquitin variant Ubv.G1.1
分子名称: Ubiquitin-conjugating enzyme E2 G1, Ubv.G1.1
著者Ceccarelli, D.F, Garg, P, Sidhu, S, Sicheri, F.
登録日2018-04-20
公開日2019-07-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes.
J.Mol.Biol., 432, 2020
6D6I
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BU of 6d6i by Molmil
Ube2V1 in complex with ubiquitin variant Ubv.V1.1 and Ube2N/Ubc13
分子名称: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 1, Ubv.V1.1
著者Ceccarelli, D.F, Garg, P, Keszei, A, Sidhu, S, Sicheri, F.
登録日2018-04-21
公開日2019-07-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.551 Å)
主引用文献Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes.
J.Mol.Biol., 432, 2020
6DJW
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BU of 6djw by Molmil
Crystal Structure of pParkin (REP and RING2 deleted)-pUb-UbcH7 complex
分子名称: RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ...
著者Sauve, V, Sung, G, Trempe, J.F, Gehring, K.
登録日2018-05-26
公開日2018-07-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.801 Å)
主引用文献Mechanism of parkin activation by phosphorylation.
Nat. Struct. Mol. Biol., 25, 2018
8EAZ
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BU of 8eaz by Molmil
HOIL-1/E2-Ub/Ub transthiolation complex
分子名称: RanBP-type and C3HC4-type zinc finger-containing protein 1, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ...
著者Wang, X.S, Cotton, T.R, Lechtenberg, B.C.
登録日2022-08-30
公開日2023-01-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family.
Nat Commun, 14, 2023
8EB0
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BU of 8eb0 by Molmil
RNF216/E2-Ub/Ub transthiolation complex
分子名称: E3 ubiquitin-protein ligase RNF216, SULFATE ION, Ubiquitin, ...
著者Cotton, T.R, Wang, X.S, Lechtenberg, B.C.
登録日2022-08-30
公開日2023-01-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family.
Nat Commun, 14, 2023
8E2F
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BU of 8e2f by Molmil
Cryo-EM structure of N-terminal arm of BIRC6 (from local refinement 2)
分子名称: Baculoviral IAP repeat-containing protein 6
著者Hunkeler, M, Fischer, E.S.
登録日2022-08-15
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.47 Å)
主引用文献Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Science, 379, 2023
8E2E
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BU of 8e2e by Molmil
Cryo-EM structure of helical arch of BIRC6 (from local refinement 1)
分子名称: Baculoviral IAP repeat-containing protein 6
著者Hunkeler, M, Fischer, E.S.
登録日2022-08-15
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (1.98 Å)
主引用文献Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Science, 379, 2023
8E2D
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BU of 8e2d by Molmil
Cryo-EM structure of BIRC6 (consensus)
分子名称: Baculoviral IAP repeat-containing protein 6
著者Hunkeler, M, Fischer, E.S.
登録日2022-08-15
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.07 Å)
主引用文献Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Science, 379, 2023
8E2K
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BU of 8e2k by Molmil
Cryo-EM structure of BIRC6/HtrA2-S306A
分子名称: Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial
著者Hunkeler, M, Fischer, E.S.
登録日2022-08-15
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Science, 379, 2023
8E2H
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BU of 8e2h by Molmil
Cryo-EM structure of C-terminal arm of BIRC6 (from local refinement 4)
分子名称: Baculoviral IAP repeat-containing protein 6
著者Hunkeler, M, Fischer, E.S.
登録日2022-08-15
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Science, 379, 2023
8E2G
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BU of 8e2g by Molmil
Cryo-EM structure of N-terminal arm (aa68-966) of BIRC6 (from local refinement 3)
分子名称: Baculoviral IAP repeat-containing protein 6
著者Hunkeler, M, Fischer, E.S.
登録日2022-08-15
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Science, 379, 2023
8E2I
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BU of 8e2i by Molmil
Cryo-EM structure of BIRC6/Smac
分子名称: Baculoviral IAP repeat-containing protein 6, Diablo IAP-binding mitochondrial protein
著者Hunkeler, M, Fischer, E.S.
登録日2022-08-15
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Science, 379, 2023
6DJX
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BU of 6djx by Molmil
Crystal Structure of pParkin-pUb-UbcH7 complex
分子名称: RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ...
著者Sauve, V, Sung, G, Trempe, J.F, Gehring, K.
登録日2018-05-27
公開日2018-07-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.801 Å)
主引用文献Mechanism of parkin activation by phosphorylation.
Nat. Struct. Mol. Biol., 25, 2018
2Y9M
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BU of 2y9m by Molmil
Pex4p-Pex22p structure
分子名称: 1,2-ETHANEDIOL, PEROXISOME ASSEMBLY PROTEIN 22, UBIQUITIN-CONJUGATING ENZYME E2-21 KDA
著者Williams, C, van den Berg, M, Panjikar, S, Distel, B, Wilmanns, M.
登録日2011-02-15
公開日2011-10-26
最終更新日2017-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights Into Ubiquitin-Conjugating Enzyme/ Co-Activator Interactions from the Structure of the Pex4P:Pex22P Complex.
Embo J., 31, 2011
7BXG
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BU of 7bxg by Molmil
MavC-UBE2N-Ub complex
分子名称: MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N
著者Gao, P, Wang, Y.
登録日2020-04-19
公開日2020-05-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Nat Commun, 11, 2020
7BBF
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BU of 7bbf by Molmil
Crystal structure of ubiquitin charged Ube2N (Ube2N~Ub) in complex with Ube2V2
分子名称: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Kiss, L, Neuhaus, D, James, L.C.
登録日2020-12-17
公開日2021-01-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination.
Nat Commun, 12, 2021
5ULH
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BU of 5ulh by Molmil
Structure of RNF165 in complex with a UbcH5b~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RNF165, GLYCEROL, THIOCYANATE ION, ...
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
5ULK
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BU of 5ulk by Molmil
Crystal Structure of RNF165 in complex with a UbcH5b~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RNF165, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ...
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
2LXP
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BU of 2lxp by Molmil
NMR structure of two domains in ubiquitin ligase gp78, RING and G2BR, bound to its conjugating enzyme Ube2g
分子名称: E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2, ZINC ION
著者Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R.
登録日2012-08-30
公開日2013-08-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
5VZW
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BU of 5vzw by Molmil
TRIM23 RING domain in complex with UbcH5-Ub
分子名称: E3 ubiquitin-protein ligase TRIM23, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ...
著者Pornillos, O, Dawidziak, D.
登録日2017-05-29
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.278 Å)
主引用文献Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase.
Proteins, 85, 2017
2XWU
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BU of 2xwu by Molmil
CRYSTAL STRUCTURE OF IMPORTIN 13 - UBC9 COMPLEX
分子名称: IMPORTIN13, SUMO-CONJUGATING ENZYME UBC9
著者Gruenwald, M, Bono, F.
登録日2010-11-05
公開日2010-12-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Importin13-Ubc9 Complex: Nuclear Import and Release of a Key Regulator of Sumoylation.
Embo J., 30, 2011
2YHO
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BU of 2yho by Molmil
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
分子名称: ACETATE ION, E3 UBIQUITIN-PROTEIN LIGASE MYLIP, UBIQUITIN-CONJUGATING ENZYME E2 D1, ...
著者Fairall, L, Goult, B.T, Millard, C.J, Tontonoz, P, Schwabe, J.W.R.
登録日2011-05-04
公開日2011-06-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
5TUT
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BU of 5tut by Molmil
UbcH5a-Ub isopeptide conjugate
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 D1
著者Sanchez, J.G, Wagner, J.M, Pornillos, O.
登録日2016-11-07
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献UbcH5a-Ub isopeptide conjugate
To be Published
3A4S
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BU of 3a4s by Molmil
The crystal structure of the SLD2:Ubc9 complex
分子名称: NFATC2-interacting protein, SUMO-conjugating enzyme UBC9
著者Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M.
登録日2009-07-14
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45
Proteins, 78, 2009

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件を2024-06-19に公開中

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