8SI0
 
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8OGY
 | | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry D04 | | 分子名称: | Cyclic di-AMP synthase CdaA, MAGNESIUM ION, methyl 4-fluoro-L-phenylalaninate | | 著者 | Garbers, T.B, Neumann, P, Wollenhaupt, J, Weiss, M.S, Ficner, R. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry D04
To Be Published
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8OGK
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8OGR
 | | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry B07 | | 分子名称: | Cyclic di-AMP synthase CdaA, MAGNESIUM ION, N-[3-(diethylamino)phenyl]ethanamide | | 著者 | Garbers, T.B, Neumann, P, Wollenhaupt, J, Weiss, M.S, Ficner, R. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry B07
To Be Published
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8OHJ
 | | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry G08 | | 分子名称: | Cyclic di-AMP synthase CdaA, MAGNESIUM ION, N-ethyl-2-{[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide | | 著者 | Garbers, T.B, Neumann, P, Wollenhaupt, J, Weiss, M.S, Ficner, R. | | 登録日 | 2023-03-21 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | | 主引用文献 | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry G08
To Be Published
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8OGM
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8OHH
 | | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry G05 | | 分子名称: | Cyclic di-AMP synthase CdaA, MAGNESIUM ION, N-phenyl-N'-propan-2-ylurea | | 著者 | Garbers, T.B, Neumann, P, Wollenhaupt, J, Weiss, M.S, Ficner, R. | | 登録日 | 2023-03-21 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry G05
To Be Published
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8OHE
 | | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry F03 | | 分子名称: | Cyclic di-AMP synthase CdaA, MAGNESIUM ION, N-(3-fluorophenyl)-2-(2-methoxyethoxy)acetamide | | 著者 | Garbers, T.B, Neumann, P, Wollenhaupt, J, Weiss, M.S, Ficner, R. | | 登録日 | 2023-03-21 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry F03
To Be Published
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8OGN
 | | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry A09 | | 分子名称: | Cyclic di-AMP synthase CdaA, MAGNESIUM ION, [1,2]thiazolo[5,4-b]pyridin-3-amine | | 著者 | Garbers, T.B, Neumann, P, Wollenhaupt, J, Weiss, M.S, Ficner, R. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | CdaA in complex with fragment F2X-Entry A09
To Be Published
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8OGS
 | | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry B08 | | 分子名称: | Cyclic di-AMP synthase CdaA, MAGNESIUM ION, ethyl 1,3-dihydro-2H-pyrrolo[3,4-c]pyridine-2-carboxylate | | 著者 | Garbers, T.B, Neumann, P, Wollenhaupt, J, Weiss, M.S, Ficner, R. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry B08
To Be Published
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8OHK
 | | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry H01 | | 分子名称: | Cyclic di-AMP synthase CdaA, MAGNESIUM ION, ~{N},~{N}-diethyl-2-(4-nitrophenoxy)ethanamine | | 著者 | Garbers, T.B, Neumann, P, Wollenhaupt, J, Weiss, M.S, Ficner, R. | | 登録日 | 2023-03-21 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry H01
To Be Published
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8OHF
 | | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry F04 | | 分子名称: | Cyclic di-AMP synthase CdaA, MAGNESIUM ION, N-[(4-bromo-3-methylphenyl)methyl]-2-(methylsulfonyl)ethan-1-amine | | 著者 | Garbers, T.B, Neumann, P, Wollenhaupt, J, Weiss, M.S, Ficner, R. | | 登録日 | 2023-03-21 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | | 主引用文献 | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry F04
To Be Published
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8OGW
 | | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry D02 | | 分子名称: | Cyclic di-AMP synthase CdaA, MAGNESIUM ION, ~{N}-[5-azanyl-2,4-bis(fluoranyl)phenyl]propane-1-sulfonamide | | 著者 | Garbers, T.B, Neumann, P, Wollenhaupt, J, Weiss, M.S, Ficner, R. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry D02
To Be Published
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8EAE
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7LT2
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8G2Q
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8SJ8
 | | Structure of binary complex of human cGAS and bound ppp(2'-5')GpG | | 分子名称: | Cyclic GMP-AMP synthase, ZINC ION, [[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | | 著者 | Wu, S, Sohn, J. | | 登録日 | 2023-04-17 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
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8SHU
 | | Structure of mouse cGAS | | 分子名称: | Cyclic GMP-AMP synthase, ZINC ION | | 著者 | Wu, S, Sohn, J. | | 登録日 | 2023-04-14 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
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8SHZ
 | | Structure of human cGAS | | 分子名称: | Cyclic GMP-AMP synthase, ZINC ION | | 著者 | Wu, S, Sohn, J. | | 登録日 | 2023-04-14 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
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7UYZ
 | | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | | 分子名称: | Cyclic GMP-AMP synthase, GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Wu, S, Gabelli, S.B, Sohn, J. | | 登録日 | 2022-05-07 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS
Nat Commun, 15, 2024
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7UZR
 | | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | | 分子名称: | Cyclic GMP-AMP synthase, MANGANESE (II) ION, Palindromic DNA18, ... | | 著者 | Wu, S, Gabelli, S.B, Sohn, J. | | 登録日 | 2022-05-09 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS
Nat Commun, 15, 2024
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7V0C
 | | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | | 分子名称: | Cyclic GMP-AMP synthase, MANGANESE (II) ION, Palindromic DNA18, ... | | 著者 | Wu, S, Gabelli, S.B, Sohn, J. | | 登録日 | 2022-05-10 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG
To Be Published
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7V0R
 | | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -ppcpG(2 ,5 )pA | | 分子名称: | Cyclic GMP-AMP synthase, MAGNESIUM ION, Palindromic DNA18, ... | | 著者 | Wu, S, Gabelli, S.B, Sohn, J. | | 登録日 | 2022-05-10 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -ppcpG(2 ,5 )pA
To Be Published
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8WR8
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2OUR
 | | crystal structure of PDE10A2 mutant D674A in complex with cAMP | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MAGNESIUM ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | | 著者 | Wang, H.C, Liu, Y.D, Hou, J, Zheng, M.Y, Robinson, H. | | 登録日 | 2007-02-12 | | 公開日 | 2007-03-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | From the Cover: Structural insight into substrate specificity of phosphodiesterase 10.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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