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PDB: 377 件

3V5D
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HLA-A2.1 KVAELVHFL
分子名称: Beta-2-microglobulin, HIV peptide KVAELVHFL, HLA class I histocompatibility antigen, ...
著者Collins, E.J, Lee, H.Y.
登録日2011-12-16
公開日2012-12-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Prediction of conformation and immunogenicity of peptides bound to MHC molecules
To be Published
3RL1
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HIV RT derived peptide complexed to HLA-A*0301
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-3 alpha chain, ...
著者Zhang, S, Liu, J, Cheng, H, Tan, S, Qi, J, Yan, J, Gao, G.F.
登録日2011-04-19
公開日2012-02-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
5SWQ
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Crystal Structure of HLA-A*0201 in complex with NA231, an influenza epitope
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Josephs, T.M, Rossjohn, J, Gras, S.
登録日2016-08-08
公開日2016-10-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Lack of Heterologous Cross-reactivity toward HLA-A*02:01 Restricted Viral Epitopes Is Underpinned by Distinct alpha beta T Cell Receptor Signatures.
J.Biol.Chem., 291, 2016
5WSH
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Structure of HLA-A2 P130
分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLY-VAL-TRP-ILE-ARG-THR-PRO-THR-ALA, ...
著者Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S.
登録日2016-12-07
公開日2017-12-20
最終更新日2019-01-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
3GIV
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Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
分子名称: Beta-2-microglobulin, HIV-1 peptide, HLA class I histocompatibility antigen, ...
著者Stewart-Jones, G, Iversen, A.K.N, Jones, E.Y.
登録日2009-03-06
公開日2009-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Nat.Immunol., 10, 2009
3WLB
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HLA-A24 in complex with HIV-1 Nef126-10(8T10F)
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
著者Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A, Han, C.
登録日2013-11-08
公開日2014-06-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Switching and emergence of CTL epitopes in HIV-1 infection
Retrovirology, 11, 2014
4K7F
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Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201
分子名称: Beta-2-microglobulin, Core protein, HLA class I histocompatibility antigen, ...
著者Meng, S.D, Zhang, Y, Wu, Y, Qi, J.X.
登録日2013-04-17
公開日2013-06-05
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The L60V variation in hepatitis B virus core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication.
J.Virol., 87, 2013
2CLR
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THREE DIMENSIONAL STRUCTURE OF A PEPTIDE EXTENDING OUT ONE END OF A CLASS I MHC BINDING SITE
分子名称: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) (ALPHA CHAIN), DECAMERIC PEPTIDE FROM CALRETICULIN
著者Collins, E.J, Garboczi, D.N, Wiley, D.C.
登録日1994-08-01
公開日1995-03-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structure of a peptide extending from one end of a class I MHC binding site.
Nature, 371, 1994
3H9H
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Human Class I MHC HLA-A2(A150P) in complex with the Tel1p peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-04-30
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
1T1Y
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Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-5V
分子名称: Beta-2-microglobulin, GAG PEPTIDE, HLA class I histocompatibility antigen, ...
著者Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y.
登録日2004-04-19
公開日2005-09-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes.
J.Biol.Chem., 281, 2006
5EU6
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HLA Class I antigen
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
登録日2015-11-18
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5C0B
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1E6 TCR in complex with HLA-A02 carrying RQFGPDFPTI
分子名称: 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ...
著者Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
登録日2015-06-12
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5YXN
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A T cell receptor in complex with HLA-A0201 restricted Hepatitis C virus NS3 peptide (KLVALGINAV)
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Hui, F.
登録日2017-12-06
公開日2018-12-12
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Capturing HCV immune escape by targeting structural based mechanism
To Be Published
5HHN
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Crystal Structure of HLA-A*0201 in complex with M1-F5L
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Gras, S, Josephs, T.M, Rossjohn, J.
登録日2016-01-11
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.
Proc.Natl.Acad.Sci.USA, 113, 2016
7L1B
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Crystal structure of HLA-A*03:01 in complex with a wild-type PIK3CA peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Ma, J, Baker, B.M.
登録日2020-12-14
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
2AV7
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BU of 2av7 by Molmil
Crystal structure of HTLV-1 TAX peptide Bound to Human Class I MHC HLA-A2 with the K66A mutation in the heavy chain.
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2005-08-29
公開日2005-10-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants.
J.Mol.Biol., 353, 2005
5ISZ
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BU of 5isz by Molmil
Crystal structure of LS01-TCR/M1-HLA-A*02 complex
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Stern, L.J, Selin, L.K, Song, I.
登録日2016-03-15
公開日2017-03-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8(+) T cell epitope.
Nat. Struct. Mol. Biol., 24, 2017
5HGD
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BU of 5hgd by Molmil
HLA*A2402 complexed with HIV nef138 Y2F mutant 10mer epitope
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
著者Shi, Y, Qi, J, Gao, G.F.
登録日2016-01-08
公開日2016-06-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Effects of a Single Escape Mutation on T Cell and HIV-1 Co-adaptation.
Cell Rep, 15, 2016
5D2N
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Crystal structure of C25-NLV-HLA-A2 complex
分子名称: ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, C25 alpha, ...
著者Mariuzza, R.A, Yang, X.
登録日2015-08-05
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.
J.Biol.Chem., 290, 2015
5HHQ
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Crystal Structure of HLA-A*0201 in complex with M1-L3W
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Gras, S, Josephs, T.M, Rossjohn, J.
登録日2016-01-11
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.
Proc.Natl.Acad.Sci.USA, 113, 2016
3GSX
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BU of 3gsx by Molmil
Crystal structure of the binary complex between HLA-A2 and HCMV NLV-T8V peptide variant
分子名称: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant T8V (NLVPMVAVV), ...
著者Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D.
登録日2009-03-27
公開日2009-08-04
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009
4UQ3
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Crystal structure of HLA-A0201 in complex with an azobenzene- containing peptide
分子名称: AZOBENZENE-CONTAINING PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Thong, S.Y, Yap, J.W, Lim, P.Y, Verhelst, S.H, Lescar, J, Meijers, R, Grotenbreg, G.M.
登録日2014-06-19
公開日2014-09-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides.
Angew. Chem. Int. Ed. Engl., 53, 2014
2X4U
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Crystal structure of MHC CLass I HLA-A2.1 bound to HIV-1 Peptide RT468-476
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ...
著者Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M.
登録日2010-02-02
公開日2010-03-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals.
J.Am.Chem.Soc., 131, 2009
5EOT
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Structure of HLA-A2:01 with peptide G13E
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Zajonc, D.M, Remesh, S.G.
登録日2015-11-10
公開日2016-12-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
2F53
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Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent cross-reactivity
分子名称: Beta-2-microglobulin, Cancer/testis antigen 1B, GLYCEROL, ...
著者Rizkallah, P.J, Jakobsen, B.K, Dunn, S.M, Sami, M.
登録日2005-11-25
公開日2006-04-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein Sci., 15, 2006

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