5H65
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![BU of 5h65 by Molmil](/molmil-images/mine/5h65) | Crystal structure of human POT1 and TPP1 | 分子名称: | Adrenocortical dysplasia protein homolog, Protection of telomeres protein 1, ZINC ION | 著者 | Chen, C, Wu, J, Lei, M. | 登録日 | 2016-11-10 | 公開日 | 2017-05-31 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer. Nat Commun, 8, 2017
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5UN7
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![BU of 5un7 by Molmil](/molmil-images/mine/5un7) | Structure of the human POT1-TPP1 telomeric complex | 分子名称: | Adrenocortical dysplasia protein homolog, POTASSIUM ION, Protection of telomeres protein 1, ... | 著者 | Rice, C, Doukov, T, Skordalakes, E. | 登録日 | 2017-01-30 | 公開日 | 2017-04-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and functional analysis of the human POT1-TPP1 telomeric complex. Nat Commun, 8, 2017
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5XYF
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![BU of 5xyf by Molmil](/molmil-images/mine/5xyf) | |
2I46
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![BU of 2i46 by Molmil](/molmil-images/mine/2i46) | Crystal structure of human TPP1 | 分子名称: | Adrenocortical dysplasia protein homolog | 著者 | Wang, F, Podell, E.R, Zaug, A.J, Yang, Y.T, Baciu, P, Else, T, Hammer, G.D, Cech, T.R, Lei, M. | 登録日 | 2006-08-21 | 公開日 | 2006-11-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature, 445, 2007
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7S1T
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![BU of 7s1t by Molmil](/molmil-images/mine/7s1t) | Structure of the human POT1-TPP1 complex | 分子名称: | Adrenocortical dysplasia protein homolog, Protection of telomeres protein 1, ZINC ION | 著者 | Aramburu, T, Skordalakes, E. | 登録日 | 2021-09-02 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance. Comput Struct Biotechnol J, 20, 2022
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5I2Y
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![BU of 5i2y by Molmil](/molmil-images/mine/5i2y) | Crystal Structure of TPP1 K170A | 分子名称: | Adrenocortical dysplasia protein homolog | 著者 | Nandakumar, J, Smith, E.M. | 登録日 | 2016-02-09 | 公開日 | 2016-11-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and functional consequences of a disease mutation in the telomere protein TPP1. Proc.Natl.Acad.Sci.USA, 113, 2016
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5I2X
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![BU of 5i2x by Molmil](/molmil-images/mine/5i2x) | Crystal Structure of TPP1 K170del | 分子名称: | Adrenocortical dysplasia protein homolog | 著者 | Nandakumar, J, Smith, E. | 登録日 | 2016-02-09 | 公開日 | 2016-11-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and functional consequences of a disease mutation in the telomere protein TPP1. Proc.Natl.Acad.Sci.USA, 113, 2016
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7QXA
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![BU of 7qxa by Molmil](/molmil-images/mine/7qxa) | Cryo-EM map of human telomerase-DNA-TPP1 complex (sharpened) | 分子名称: | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... | 著者 | Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. | 登録日 | 2022-01-26 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
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7TRE
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![BU of 7tre by Molmil](/molmil-images/mine/7tre) | Human telomerase catalytic core with shelterin protein TPP1 | 分子名称: | Adrenocortical dysplasia protein homolog, Telomerase RNA, partial sequence, ... | 著者 | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | 登録日 | 2022-01-28 | 公開日 | 2022-04-20 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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8SOJ
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![BU of 8soj by Molmil](/molmil-images/mine/8soj) | |
7QXS
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![BU of 7qxs by Molmil](/molmil-images/mine/7qxs) | Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains) | 分子名称: | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... | 著者 | Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. | 登録日 | 2022-01-27 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
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7QXB
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![BU of 7qxb by Molmil](/molmil-images/mine/7qxb) | Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map) | 分子名称: | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... | 著者 | Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. | 登録日 | 2022-01-26 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
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8SOK
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![BU of 8sok by Molmil](/molmil-images/mine/8sok) | |