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PDB: 319 件

5B0Y
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Crystal structure of the nucleosome containing histone H3 with the crotonylated lysine 122
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Suzuki, Y, Horikoshi, N, Kurumizaka, H.
登録日2015-11-13
公開日2016-01-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.557 Å)
主引用文献Crystal structure of the nucleosome containing histone H3 with crotonylated lysine 122
Biochem.Biophys.Res.Commun., 469, 2016
7XCR
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Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 1:1 complex
分子名称: DNA (146-MER), Histone H2A, Histone H2B type 1-K, ...
著者Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L.
登録日2022-03-25
公開日2022-04-20
最終更新日2022-09-07
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
6T7F
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RCR E3 ligase E2-Ubiquitin transthiolation intermediate
分子名称: 3,3-bis(sulfanyl)-~{N}-(1~{H}-1,2,3-triazol-4-ylmethyl)propanamide, E3 ubiquitin-protein ligase MYCBP2, Polyubiquitin-C, ...
著者Mabbitt, P.D, Virdee, S.
登録日2019-10-21
公開日2020-08-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity.
Nat.Chem.Biol., 16, 2020
5ZBX
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The crystal structure of the nucleosome containing histone H3.1 CATD(V76Q, K77D)
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Arimura, Y, Takagi, H, Kurumizaka, H.
登録日2018-02-13
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism.
Nat Commun, 10, 2019
5XF3
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Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,R-configuration)
分子名称: (1R,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
6LE9
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BU of 6le9 by Molmil
The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties
分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Histone H3.1, ...
著者Soman, A, Liew, C.W, Teo, H.L, Berezhnoy, N, Korolev, N, Rhodes, D, Nordenskiold, L.
登録日2019-11-24
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The human telomeric nucleosome displays distinct structural and dynamic properties.
Nucleic Acids Res., 48, 2020
6L9H
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The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties
分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Histone H3.1, ...
著者Soman, A, Liew, C.W, Teo, H.L, Berezhnoy, N, Korolev, N, Rhodes, D, Nordenskiold, L.
登録日2019-11-10
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The human telomeric nucleosome displays distinct structural and dynamic properties.
Nucleic Acids Res., 48, 2020
6E0P
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Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Yadav, K.N.S, Zhou, B.-R.
登録日2018-07-06
公開日2019-05-22
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment.
Nat Commun, 10, 2019
8SYP
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BU of 8syp by Molmil
Genomic CX3CR1 nucleosome
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2023-05-25
公開日2023-11-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
4GB0
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BU of 4gb0 by Molmil
Crystal Structure of the RING domain of RNF168
分子名称: E3 ubiquitin-protein ligase RNF168, MALONATE ION, ZINC ION
著者Zhang, X.Q, Wang, C.L, Zang, J.Y.
登録日2012-07-26
公開日2013-07-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for role of ring finger protein RNF168 RING domain
Cell Cycle, 12, 2013
6V2K
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BU of 6v2k by Molmil
The nucleosome structure after H2A-H2B exchange
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A, ...
著者Arimura, Y, Hirano, R, Kurumizaka, H.
登録日2019-11-24
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome.
Commun Biol, 4, 2021
7U0G
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BU of 7u0g by Molmil
structure of LIN28b nucleosome bound 3 OCT4
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2022-02-18
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
7U0I
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Structure of LIN28b nucleosome bound 2 OCT4
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Tengfei, L, Guan, R, Bai, Y.
登録日2022-02-18
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
5B2J
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BU of 5b2j by Molmil
Human nucleosome containing CpG methylated DNA
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Fujii, Y, Wakamori, M, Umehara, T, Yokoyama, S.
登録日2016-01-18
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation.
Febs Open Bio, 6, 2016
6A7U
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BU of 6a7u by Molmil
Crystal structure of histone H2A.Bbd-H2B dimer
分子名称: Histone H2B type 2-E,Histone H2A-Bbd type 2/3
著者Dai, L, Zhou, Z.
登録日2018-07-04
公開日2019-02-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the histone heterodimer containing histone variant H2A.Bbd.
Biochem. Biophys. Res. Commun., 503, 2018
8Q36
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BU of 8q36 by Molmil
Structure of Nucleosome Core with a Bound Metallopeptide Conjugate (Foamy Virus GAG Peptide-Au[I] Compound)
分子名称: DNA (145-MER), GAG structural protein, Histone H2A type 1-B/E, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-03
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
4NFT
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BU of 4nft by Molmil
Crystal structure of human lnkH2B-h2A.Z-Anp32e
分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member E, Histone H2B type 2-E, Histone H2A.Z
著者Shan, S, Pan, L, Mao, Z, Wang, W, Sun, J, Dong, Q, Liang, X, Ding, X, Chen, S, Dai, L, Zhang, Z, Zhu, B, Zhou, Z.
登録日2013-11-01
公開日2014-04-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z
Cell Res., 24, 2014
8UQC
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BU of 8uqc by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 2)
分子名称: E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, ZINC ION
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
6E0C
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BU of 6e0c by Molmil
Cryo-EM structure of the CENP-A nucleosome (W601) in complex with a single chain antibody fragment
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Yadav, K.N.S, Zhou, B.-R.
登録日2018-07-06
公開日2019-05-22
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (2.63 Å)
主引用文献Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment.
Nat Commun, 10, 2019
5CPK
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BU of 5cpk by Molmil
Nucleosome containing methylated Sat2L DNA
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Osakabe, A, Arimura, Y, Adachi, F, Maehara, K, Ohkawa, Y, Kurumizaka, H.
登録日2015-07-21
公開日2015-10-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.632 Å)
主引用文献Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA.
Open Biology, 5, 2015
8EVI
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BU of 8evi by Molmil
CX3CR1 nucleosome and PU.1 complex containing disulfide bond mutations
分子名称: DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2022-10-20
公開日2023-11-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
3RPG
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BU of 3rpg by Molmil
Bmi1/Ring1b-UbcH5c complex structure
分子名称: E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1, Ubiquitin-conjugating enzyme E2 D3, ...
著者Bentley, M.L, Dong, K.C, Cochran, A.G.
登録日2011-04-26
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6485 Å)
主引用文献Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex.
Embo J., 30, 2011
8JL9
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BU of 8jl9 by Molmil
Cryo-EM structure of the human nucleosome with scFv
分子名称: DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-02
公開日2023-10-04
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
3WTP
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Crystal Structure of the heterotypic nucleosome containing human CENP-A and H3.3
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Arimura, Y, Shirayama, K, Horikoshi, N, Fujita, R, Kagawa, W, Fukagawa, T, Almouzni, G, Kurumizaka, H.
登録日2014-04-14
公開日2014-12-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Crystal structure and stable property of the cancer-associated heterotypic nucleosome containing CENP-A and H3.3
Sci Rep, 4, 2014
8YBK
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Cryo-EM structure of the human nucleosome containing the H3.1 E97K mutant
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2024-02-14
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K.
Genes Cells, 2024

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件を2024-07-31に公開中

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