4WZO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wzo by Molmil](/molmil-images/mine/4wzo) | Complex of 70S ribosome with tRNA-fMet and mRNA | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2014-11-20 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
|
|
4V8C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v8c by Molmil](/molmil-images/mine/4v8c) | Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex with paromomycin). | 分子名称: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2011-12-07 | 公開日 | 2014-07-09 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
|
|
7AZO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7azo by Molmil](/molmil-images/mine/7azo) | 70S thermus thermophilus ribosome with bound antibiotic lead SEQ-977 | 分子名称: | (2R,3S,4R,5R,7S,9S,10S,11R,12S,13R)-12-(((2R,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2-((S)-1-(((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)-10-(((2S,3R,4R,6R)-3-hydroxy-4-(methoxyamino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-7-(((2-((2-nitrophenyl)sulfonamido)ethyl)carbamoyl)oxy)-6,14-dioxooxacyclotetradecan-4-yl 3-methylbutanoate, 16S rRNA, 23S rRNA, ... | 著者 | Jenner, L.B, Yusupov, M, Yusupova, G. | 登録日 | 2020-11-17 | 公開日 | 2022-06-01 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents. Cell, 186, 2023
|
|
5VPO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vpo by Molmil](/molmil-images/mine/5vpo) | The 70S P-site ASL SufA6 complex | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | 登録日 | 2017-05-05 | 公開日 | 2018-09-26 | 最終更新日 | 2018-11-07 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
4V8X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v8x by Molmil](/molmil-images/mine/4v8x) | Structure of Thermus thermophilus ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Feng, S, Chen, Y, Kamada, K, Wang, H, Tang, K, Wang, M, Gao, Y.G. | 登録日 | 2013-07-19 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Yoeb-Ribosome Structure: A Canonical Rnase that Requires the Ribosome for its Specific Activity. Nucleic Acids Res., 41, 2013
|
|
6GSK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gsk by Molmil](/molmil-images/mine/6gsk) | Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNAThr in the A-site | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Yusupov, M, Yusupova, G. | 登録日 | 2018-06-14 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | 主引用文献 | Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria. Nucleic Acids Res., 46, 2018
|
|
6NSH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nsh by Molmil](/molmil-images/mine/6nsh) | Modified ASL proline bound to Thermus thermophilus 70S (near-cognate) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M. | 登録日 | 2019-01-24 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.397 Å) | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife, 9, 2020
|
|
4V84
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v84 by Molmil](/molmil-images/mine/4v84) | Crystal structure of a complex containing domain 3 of CrPV IGR IRES RNA bound to the 70S ribosome. | 分子名称: | 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S. | 登録日 | 2010-12-13 | 公開日 | 2014-07-09 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
4V9N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v9n by Molmil](/molmil-images/mine/4v9n) | Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2. | 分子名称: | 16S rRNA (1504-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Santos, N, Zhu, J, Donohue, J.P, Korostelev, A.A, Noller, H.F. | 登録日 | 2013-04-26 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2. Structure, 21, 2013
|
|
4WT8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wt8 by Molmil](/molmil-images/mine/4wt8) | Crystal Structure of bactobolin A bound to 70S ribosome-tRNA complex | 分子名称: | 23S rRNA (2899-MER), 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Amunts, A, Fiedorczuk, K, Ramakrishnan, V. | 登録日 | 2014-10-29 | 公開日 | 2015-01-21 | 最終更新日 | 2018-07-18 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics. J.Mol.Biol., 427, 2015
|
|
4V9Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v9q by Molmil](/molmil-images/mine/4v9q) | Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Svidritskiy, E, Ling, C, Ermolenko, D.N, Korostelev, A.A. | 登録日 | 2013-06-12 | 公開日 | 2014-07-09 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
6B4V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b4v by Molmil](/molmil-images/mine/6b4v) | |
6BOH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6boh by Molmil](/molmil-images/mine/6boh) | |
4YPB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ypb by Molmil](/molmil-images/mine/4ypb) | Precleavage 70S structure of the P. vulgaris HigB DeltaH92 toxin bound to the AAA codon | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | 登録日 | 2015-03-12 | 公開日 | 2015-10-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Defining the mRNA recognition signature of a bacterial toxin protein. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
1VVJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vvj by Molmil](/molmil-images/mine/1vvj) | Crystal Structure of Frameshift Suppressor tRNA SufA6 bound to Codon CCC-G on the Ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Maehigashi, T, Dunkle, J.A, Dunham, C.M. | 登録日 | 2013-05-24 | 公開日 | 2014-08-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.440001 Å) | 主引用文献 | Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4V5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v5e by Molmil](/molmil-images/mine/4v5e) | Insights into translational termination from the structure of RF2 bound to the ribosome | 分子名称: | 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Weixlbaumer, A, Jin, H, Neubauer, C, Voorhees, R.M, Petry, S, Kelley, A.C, Ramakrishnan, V. | 登録日 | 2009-04-30 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Insights Into Translational Termination from the Structure of Rf2 Bound to the Ribosome. Science, 322, 2008
|
|
4V7M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v7m by Molmil](/molmil-images/mine/4v7m) | |
4LSK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lsk by Molmil](/molmil-images/mine/4lsk) | Crystal Structure of tRNA Proline (CGG) Bound to Codon CCG-G on the Ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Maehigashi, T, Dunkle, J.A, Dunham, C.M. | 登録日 | 2013-07-22 | 公開日 | 2014-08-06 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3.48000622 Å) | 主引用文献 | Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
6OXI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oxi by Molmil](/molmil-images/mine/6oxi) | Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (UAA) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | 登録日 | 2019-05-13 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.495 Å) | 主引用文献 | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res., 47, 2019
|
|
4V5A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v5a by Molmil](/molmil-images/mine/4v5a) | Structure of the Ribosome Recycling Factor bound to the Thermus thermophilus 70S ribosome with mRNA, ASL-Phe and tRNA-fMet | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Weixlbaumer, A, Petry, S, Dunham, C.M, Selmer, M, Kelley, A.C, Ramakrishnan, V. | 登録日 | 2007-06-28 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structure of the ribosome recycling factor bound to the ribosome. Nat. Struct. Mol. Biol., 14, 2007
|
|
4V9L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v9l by Molmil](/molmil-images/mine/4v9l) | 70S Ribosome translocation intermediate FA-3.6A containing elongation factor EFG/FUSIDIC ACID/GDP, mRNA, and tRNA bound in the pe*/E state. | 分子名称: | 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F. | 登録日 | 2013-04-24 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation. Science, 340, 2013
|
|
4V6G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v6g by Molmil](/molmil-images/mine/4v6g) | Initiation complex of 70S ribosome with two tRNAs and mRNA. | 分子名称: | 16S RRNA (E.COLI NUMBERING), 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Jenner, L.B, Yusupova, G, Yusupov, M. | 登録日 | 2009-07-10 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural aspects of messenger RNA reading frame maintenance by the ribosome. Nat.Struct.Mol.Biol., 17, 2010
|
|
4V9K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v9k by Molmil](/molmil-images/mine/4v9k) | 70S ribosome translocation intermediate GDPNP-I containing elongation factor EFG/GDPNP, mRNA, and tRNA bound in the pe*/E state. | 分子名称: | 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F. | 登録日 | 2013-04-24 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation. Science, 340, 2013
|
|
4TUE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4tue by Molmil](/molmil-images/mine/4tue) | |
4V83
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v83 by Molmil](/molmil-images/mine/4v83) | Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S ribosome. | 分子名称: | 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S. | 登録日 | 2010-12-13 | 公開日 | 2014-07-09 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|