Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 92 件
4JK8
DownloadVisualize
BU of 4jk8 by Molmil
Open and closed forms of R1865A human PRP8 RNase H-like domain with bound Mg ion
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKB
DownloadVisualize
BU of 4jkb by Molmil
Open and closed forms of V1788D human PRP8 RNase H-like domain with bound Mg ion
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKA
DownloadVisualize
BU of 4jka by Molmil
Open and closed forms of R1865A human PRP8 RNase H-like domain with bound Co ion
分子名称: CHLORIDE ION, COBALT (II) ION, Pre-mRNA-processing-splicing factor 8
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JK7
DownloadVisualize
BU of 4jk7 by Molmil
Open and closed forms of wild-type human PRP8 RNase H-like domain with bound Mg ion
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JK9
DownloadVisualize
BU of 4jk9 by Molmil
Open and closed forms of wild-type human PRP8 RNase H-like domain with bound Co ion
分子名称: CHLORIDE ION, COBALT (II) ION, GLYCEROL, ...
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKC
DownloadVisualize
BU of 4jkc by Molmil
Open and closed forms of T1800E human PRP8 RNase H-like domain with bound Mg ion
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKD
DownloadVisualize
BU of 4jkd by Molmil
Open and closed forms of I1790Y human PRP8 RNase H-like domain with bound Mg ion
分子名称: CHLORIDE ION, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKE
DownloadVisualize
BU of 4jke by Molmil
Open and closed forms of T1789P human PRP8 RNase H-like domain with bound Mg ion
分子名称: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKG
DownloadVisualize
BU of 4jkg by Molmil
Open and closed forms of mixed T1789P+R1865A and R1865A human PRP8 RNase H-like domain with bound Mg ion
分子名称: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKH
DownloadVisualize
BU of 4jkh by Molmil
Open and closed forms of D1781E human PRP8 RNase H-like domain with bound Mg ion
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
3LRU
DownloadVisualize
BU of 3lru by Molmil
hPRP8 Non-Native Subdomain
分子名称: Pre-mRNA-processing-splicing factor 8
著者Schellenberg, M.J, Ritchie, D.B, MacMillan, A.M.
登録日2010-02-11
公開日2010-08-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Context-dependent remodeling of structure in two large protein fragments.
J.Mol.Biol., 402, 2010
3ENB
DownloadVisualize
BU of 3enb by Molmil
Crystal Structure of PRP8 core domain IV
分子名称: Pre-mRNA-processing-splicing factor 8
著者Schellenberg, M.J, Ritchie, D.B, MacMillan, A.M.
登録日2008-09-25
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural elucidation of a PRP8 core domain from the heart of the spliceosome.
Nat.Struct.Mol.Biol., 15, 2008
4JKF
DownloadVisualize
BU of 4jkf by Molmil
Open and closed forms of T1791P+R1865A human PRP8 RNase H-like domain with bound Mg ion
分子名称: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
3E9L
DownloadVisualize
BU of 3e9l by Molmil
Crystal Structure of Human Prp8, Residues 1755-2016
分子名称: CHLORIDE ION, Pre-mRNA-processing-splicing factor 8, SODIUM ION
著者Pena, V, Rozov, A, Wahl, M.C.
登録日2008-08-22
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and function of an RNase H domain at the heart of the spliceosome.
Embo J., 27, 2008
8BCE
DownloadVisualize
BU of 8bce by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 76
分子名称: 1,2-ETHANEDIOL, N-methoxybenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
8BC9
DownloadVisualize
BU of 8bc9 by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 24
分子名称: 1,2-ETHANEDIOL, N-hydroxybenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
8BCC
DownloadVisualize
BU of 8bcc by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 39
分子名称: 1,2-ETHANEDIOL, 3-oxidanylbenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
7PJH
DownloadVisualize
BU of 7pjh by Molmil
Crystal structure of the human spliceosomal maturation factor AAR2 bound to the RNAse H domain of PRPF8
分子名称: Pre-mRNA-processing-splicing factor 8, Protein AAR2 homolog
著者Preussner, M, Santos, K, Heroven, A.C, Alles, J, Heyd, F, Wahl, M.C, Weber, G.
登録日2021-08-24
公開日2022-11-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural and functional investigation of the human snRNP assembly factor AAR2 in complex with the RNase H-like domain of PRPF8.
Acta Crystallogr D Struct Biol, 78, 2022
8BCB
DownloadVisualize
BU of 8bcb by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 34
分子名称: 1,2-ETHANEDIOL, Pre-mRNA-processing-splicing factor 8, SULFANILAMIDE, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
8BCG
DownloadVisualize
BU of 8bcg by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 86
分子名称: 1,2-ETHANEDIOL, 4-chloranyl-~{N}-methoxy-~{N}-methyl-benzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
8BC8
DownloadVisualize
BU of 8bc8 by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 18
分子名称: 1,2-ETHANEDIOL, 3-azanyl-4-oxidanyl-benzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
6S8Q
DownloadVisualize
BU of 6s8q by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1
分子名称: Pre-mRNA-processing-splicing factor 8, SULFATE ION, U5 small nuclear ribonucleoprotein 200 kDa helicase
著者Santos, K.F, Vester, K, Wahl, M.C.
登録日2019-07-10
公開日2020-01-22
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.391 Å)
主引用文献The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit.
J.Biol.Chem., 295, 2020
8BCF
DownloadVisualize
BU of 8bcf by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 78
分子名称: 1,2-ETHANEDIOL, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
7BDK
DownloadVisualize
BU of 7bdk by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C.
登録日2020-12-21
公開日2021-06-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021
7BDJ
DownloadVisualize
BU of 7bdj by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and mant-ATPgammaS
分子名称: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ...
著者Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C.
登録日2020-12-21
公開日2021-06-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021

 

1234>

222926

件を2024-07-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon