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PDB: 10 件
6UJO
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BU of 6ujo by Molmil
HHAT L75F Neoantigen Peptide KQWLVWLFL Presented by HLA-A206
分子名称: Beta-2-microglobulin, MHC class I antigen, Protein-cysteine N-palmitoyltransferase HHAT
著者Devlin, J.R, Baker, B.M, Vander Kooi, C.
登録日2019-10-03
公開日2020-08-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Nat.Chem.Biol., 16, 2020
6UJQ
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BU of 6ujq by Molmil
HHAT Wild Type Peptide KQWLVWLLL Presented by HLA-A206
分子名称: Beta-2-microglobulin, MHC class I antigen, Protein-cysteine N-palmitoyltransferase HHAT
著者Devlin, J.R, Baker, B.M, Singh, N.K.
登録日2019-10-03
公開日2020-08-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Nat.Chem.Biol., 16, 2020
7MHY
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BU of 7mhy by Molmil
Human Hedgehog acyltransferase (HHAT) in complex with palmitoyl-CoA and two Fab antibody fragments
分子名称: 1C06 Fab heavy chain, 1C06 Fab light chain, 3H02 Fab heavy chain, ...
著者Long, S.B, Jiang, Y.
登録日2021-04-16
公開日2021-06-16
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Substrate and product complexes reveal mechanisms of Hedgehog acylation by HHAT.
Science, 372, 2021
6UK4
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BU of 6uk4 by Molmil
Complex of T cell Receptor with HHAT Neoantigen Peptide KQWLVWLFL Presented by HLA-A206
分子名称: 302 TIL T cell receptor alpha chain, 302 TIL T cell receptor beta chain, Beta-2-microglobulin, ...
著者Devlin, J.R, Baker, B.M.
登録日2019-10-04
公開日2020-08-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Nat.Chem.Biol., 16, 2020
7Q1U
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BU of 7q1u by Molmil
Structure of Hedgehog acyltransferase (HHAT) in complex with megabody 177 bound to non-hydrolysable palmitoyl-CoA (Composite Map)
分子名称: CHOLESTEROL, MAGNESIUM ION, Megabody 177, ...
著者Coupland, C, Carrique, L, Siebold, C.
登録日2021-10-21
公開日2022-06-08
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structure, mechanism, and inhibition of Hedgehog acyltransferase.
Mol.Cell, 81, 2021
7URF
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BU of 7urf by Molmil
Human HHAT H379C in complex with SHH N-terminal peptide
分子名称: 3H02 heavy chain, 3H02 light chain, Digitonin, ...
著者Liu, Y, Qi, X, Li, X.
登録日2022-04-21
公開日2022-07-20
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanisms and inhibition of Porcupine-mediated Wnt acylation.
Nature, 607, 2022
6P64
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BU of 6p64 by Molmil
Alpha-beta TCR Binding to Neoantigen KQWLVWLFL Presented by HLA-A206
分子名称: 302TIL TCR alpha chain, 302TIL TCR beta chain, Beta-2-microglobulin, ...
著者Devlin, J.R, Baker, B.M.
登録日2019-05-31
公開日2020-06-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献A T cell receptor peptide/MHC complex at 3.05 Angstrom resolution
To be Published
6UK2
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BU of 6uk2 by Molmil
Complex of T cell Receptor with HHAT Wild Type Peptide KQWLVWLLL Presented by HLA-A206
分子名称: 302 TIL T cell receptor alpha chain, 302 TIL T cell receptor beta chain, Beta-2-microglobulin, ...
著者Devlin, J.R, Baker, B.M.
登録日2019-10-04
公開日2020-08-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.138808 Å)
主引用文献Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Nat.Chem.Biol., 16, 2020
7MHZ
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BU of 7mhz by Molmil
Human Hedgehog acyltransferase (HHAT) in complex with a palmitoylated Hedgehog peptide product and a Fab antibody fragment
分子名称: 3H02 Fab heavy chain, 3H02 Fab light chain, Digitonin, ...
著者Long, S.B, Jiang, Y.
登録日2021-04-16
公開日2021-06-16
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Substrate and product complexes reveal mechanisms of Hedgehog acylation by HHAT.
Science, 372, 2021
7Q6Z
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BU of 7q6z by Molmil
Structure of Hedgehog acyltransferase (HHAT) in complex with megabody 177 bound to IMP-1575
分子名称: 2-(2-methylpropylamino)-1-[(4R)-4-(6-methylpyridin-2-yl)-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone, CHOLESTEROL, Megabody 177, ...
著者Coupland, C, Carrique, L, Siebold, C.
登録日2021-11-09
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Structure, mechanism, and inhibition of Hedgehog acyltransferase.
Mol.Cell, 81, 2021

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件を2024-07-10に公開中

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