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PDB: 404 件

3ZZP
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Circular permutant of ribosomal protein S6, lacking edge strand beta- 2 of wild-type S6.
分子名称: RIBOSOMAL PROTEIN S6
著者Saraboji, K, Haglund, E, Lindberg, M.O, Oliveberg, M, Logan, D.T.
登録日2011-09-02
公開日2011-11-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献Trimming Down a Protein Structure to its Bare Foldons: Spatial Organization of the Cooperative Unit.
J.Biol.Chem., 287, 2012
6I6E
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BU of 6i6e by Molmil
Circular permutant of ribosomal protein S6, swap strand 1 , L10A mutant
分子名称: 30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2018-11-15
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
6I69
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BU of 6i69 by Molmil
Circular permutant of ribosomal protein S6, adding 5aa to C terminal of P97-3, L10A mutant
分子名称: 30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2018-11-15
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
6I6S
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BU of 6i6s by Molmil
Circular permutant of ribosomal protein S6, adding 9aa to C terminal of P68-69, L75A mutant
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6, POTASSIUM ION, SODIUM ION
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2018-11-15
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
6I6W
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BU of 6i6w by Molmil
Circular permutant of ribosomal protein S6, adding 6aa to C terminal of P68-69
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2018-11-15
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
6I6I
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BU of 6i6i by Molmil
Circular permutant of ribosomal protein S6, adding 6aa to C terminal of P68-69, L75A mutant
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6, SULFATE ION
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2018-11-15
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
6I6U
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BU of 6i6u by Molmil
Circular permutant of ribosomal protein S6, adding 9aa to N terminal of P81-82, L75A mutant
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2018-11-15
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
7OS7
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BU of 7os7 by Molmil
Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2021-06-08
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant
To Be Published
1CQM
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BU of 1cqm by Molmil
PROTEIN AGGREGATION AND ALZHEIMER'S DISEASE: CRYSTALLOGRAPHIC ANALYSIS OF THE PHENOMENON. ENGINEERED VERSION OF THE RIBOSOMAL PROTEIN S6 USED AS A STABLE SCAFFOLD TO STUDY OLIGOMERIZATION.
分子名称: RIBOSOMAL PROTEIN S6
著者Kristensen, O, Otzen, D.E, Oliveberg, M.
登録日1999-08-08
公開日2000-09-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Designed protein tetramer zipped together with a hydrophobic Alzheimer homology: a structural clue to amyloid assembly.
Proc.Natl.Acad.Sci.USA, 97, 2000
7BFF
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BU of 7bff by Molmil
Circular permutant of ribosomal protein S6, P54-55 truncated, I25A mutant.
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2021-01-02
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Circular permutant of ribosomal protein S6
To Be Published
7B8V
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BU of 7b8v by Molmil
Circular permutant of ribosomal protein S6, P54-55
分子名称: 30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2020-12-13
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.863 Å)
主引用文献Circular permutant of ribosomal protein S6, P54-55
To Be Published
6I6O
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BU of 6i6o by Molmil
Circular permutant of ribosomal protein S6, swap helix 2, L75A mutant
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2018-11-15
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BFE
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BU of 7bfe by Molmil
Circular permutant of ribosomal protein S6, P54-55 truncated, L21A mutant.
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6, IODIDE ION
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2021-01-02
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Circular permutant of ribosomal protein S6
To Be Published
7BFG
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BU of 7bfg by Molmil
Circular permutant of ribosomal protein S6, P54-55 truncated, V37A mutant.
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2021-01-02
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Circular permutant of ribosomal protein S6
To Be Published
7B90
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BU of 7b90 by Molmil
Circular permutant of ribosomal protein S6, P54-55 truncated, I8A mutant
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2020-12-13
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Circular permutant of ribosomal protein S6, P54-55 truncate, I8A
To Be Published
7BFC
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BU of 7bfc by Molmil
Circular permutant of ribosomal protein S6, P54-55 truncated,
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2021-01-02
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Circular permutant of ribosomal protein S6
To Be Published
6I6Y
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BU of 6i6y by Molmil
Circular permutant of ribosomal protein S6, swap helix 2
分子名称: 30S ribosomal protein S6,30S ribosomal protein S6
著者Wang, H, Logan, D.T, Oliveberg, M.
登録日2018-11-15
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
8CVL
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BU of 8cvl by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMTHSMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.30A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S.
登録日2022-05-18
公開日2022-10-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes.
Nat.Chem., 15, 2023
4Y4O
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BU of 4y4o by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to protein Y (YfiA) at 2.3A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Polikanov, Y.S, Melnikov, S.V, Soll, D, Steitz, T.A.
登録日2015-02-10
公開日2015-03-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
8FC6
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BU of 8fc6 by Molmil
Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and telithromycin at 2.35A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S.
登録日2022-12-01
公開日2023-07-26
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A.
Nat Commun, 14, 2023
4W2F
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BU of 4w2f by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with amicoumacin, mRNA and three deacylated tRNAs in the A, P and E sites
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
8CVJ
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BU of 8cvj by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMSEAC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.40A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S.
登録日2022-05-18
公開日2022-10-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes.
Nat.Chem., 15, 2023
6XHV
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BU of 6xhv by Molmil
Crystal structure of the A2058-dimethylated Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A- and P-site tRNAs, and deacylated E-site tRNA at 2.40A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S.
登録日2020-06-19
公開日2020-12-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance.
Nat.Chem.Biol., 17, 2021
7RQE
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BU of 7rqe by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site deacylated tRNA analog CACCA, P-site MAI-tripeptidyl-tRNA analog ACCA-IAM, and chloramphenicol at 2.40A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S.
登録日2021-08-06
公開日2022-01-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol.
Nat.Struct.Mol.Biol., 29, 2022
7RQA
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BU of 7rqa by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site MTI-tripeptidyl-tRNA analog ACCA-ITM at 2.40A resolution
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, ...
著者Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S.
登録日2021-08-06
公開日2022-01-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol.
Nat.Struct.Mol.Biol., 29, 2022

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