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PDB: 243 件
6XQE
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BU of 6xqe by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UAA-mRNA, and deacylated P-site tRNA at 3.00A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S.
登録日2020-07-09
公開日2020-08-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 117, 2020
5HAU
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BU of 5hau by Molmil
Crystal structure of antimicrobial peptide Bac7(1-19) bound to the Thermus thermophilus 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A.
登録日2015-12-30
公開日2016-04-06
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
Nucleic Acids Res., 44, 2016
5J3C
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BU of 5j3c by Molmil
Thermus thermophilus 70S termination complex containing E. coli RF1
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Dunham, C.M.
登録日2016-03-30
公開日2016-10-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
4WRA
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BU of 4wra by Molmil
Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site and with antibiotic paromomycin.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-23
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WRO
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BU of 4wro by Molmil
Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-24
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WR6
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BU of 4wr6 by Molmil
Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-23
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WT1
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BU of 4wt1 by Molmil
Complex of 70S ribosome with tRNA-Phe and mRNA with A-A mismatch in the second position in the A-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-29
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
7JQM
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BU of 7jqm by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-002, mRNA, and deacylated P-site tRNA at 3.05A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M.
登録日2020-08-11
公開日2020-08-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens.
J.Med.Chem., 63, 2020
5DFE
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BU of 5dfe by Molmil
70S termination complex containing E. coli RF2
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Hoffer, E.D, Dunham, C.M.
登録日2015-08-26
公開日2016-10-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.09997559 Å)
主引用文献Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
4V7Z
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BU of 4v7z by Molmil
Structure of the Thermus thermophilus 70S ribosome complexed with telithromycin.
分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A.
登録日2010-08-18
公開日2014-07-09
最終更新日2021-01-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V5S
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BU of 4v5s by Molmil
The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a cognate codon on the 70S ribosome.
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
登録日2010-12-07
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V8H
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BU of 4v8h by Molmil
Crystal structure of HPF bound to the 70S ribosome.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Blaha, G.M, Steitz, T.A.
登録日2011-12-11
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis.
Science, 336, 2012
4V5R
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BU of 4v5r by Molmil
The crystal structure of EF-Tu and Trp-tRNA-Trp bound to a cognate codon on the 70S ribosome.
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
登録日2010-12-07
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V9B
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BU of 4v9b by Molmil
Crystal Structure of the 70S ribosome with tigecycline.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Jenner, L, Yusupov, M, Yusupova, G.
登録日2012-07-18
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V5J
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BU of 4v5j by Molmil
Structure of the 70S ribosome bound to Release factor 2 and a substrate analog provides insights into catalysis of peptide release
分子名称: 16S Ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Jin, H, Kelley, A.C, Loakes, D, Ramakrishnan, V.
登録日2010-03-24
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release.
Proc. Natl. Acad. Sci. U.S.A., 107, 2010
4V9S
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BU of 4v9s by Molmil
Crystal structure of antibiotic GE82832 bound to 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A.
登録日2013-12-05
公開日2014-07-09
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
4V5L
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BU of 4v5l by Molmil
The structure of EF-Tu and aminoacyl-tRNA bound to the 70S ribosome with a GTP analog
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Voorhees, R.M, Schmeing, T.M, Ramakrishnan, V.
登録日2010-09-02
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The Mechanism for Activation of GTP Hydrolysis on the Ribosome.
Science, 330, 2010
4V6F
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BU of 4v6f by Molmil
Elongation complex of the 70S ribosome with three tRNAs and mRNA.
分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 23S RRNA, ...
著者Jenner, L.B, Yusupova, G, Yusupov, M.
登録日2009-07-09
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural aspects of messenger RNA reading frame maintenance by the ribosome.
Nat.Struct.Mol.Biol., 17, 2010
4V8Q
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BU of 4v8q by Molmil
Complex of SmpB, a tmRNA fragment and EF-Tu-GDP-Kirromycin with the 70S ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Neubauer, C, Gillet, R, Kelley, A.C, Ramakrishnan, V.
登録日2011-12-10
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Decoding in the absence of a codon by tmRNA and SmpB in the ribosome.
Science, 335, 2012
4V5P
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BU of 4v5p by Molmil
The crystal structure of EF-Tu and A9C-tRNA-Trp bound to a near- cognate codon on the 70S ribosome
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
登録日2010-12-07
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V6A
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BU of 4v6a by Molmil
Structure of EF-P bound to the 70S ribosome.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Stanley, R.E, Blaha, G.
登録日2009-06-15
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome.
Science, 325, 2009
4V8N
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BU of 4v8n by Molmil
The crystal structure of agmatidine tRNA-Ile2 bound to the 70S ribosome in the A and P site.
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Voorhees, R.M, Mandal, D, Neubauer, C, Koehrer, C, RajBhandary, U.L, Ramakrishnan, V.
登録日2013-02-13
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The Structural Basis for Specific Decoding of Aua by Isoleucine tRNA on the Ribosome
Nat.Struct.Mol.Biol., 20, 2013
4WQ1
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BU of 4wq1 by Molmil
Complex of 70S ribosome with tRNA-Tyr and mRNA with C-A mismatch in the first position in the A-site.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-21
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
6OPE
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BU of 6ope by Molmil
Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to near-cognate 70S A site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-04-24
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
6QNR
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BU of 6qnr by Molmil
70S ribosome elongation complex (EC) with experimentally assigned potassium ions
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Khusainov, I, Yusupov, M, Yusupova, G.
登録日2019-02-11
公開日2019-06-19
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction.
Nat Commun, 10, 2019

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