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PDB: 12 件
8F38
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BU of 8f38 by Molmil
Cryo-EM structure of X6 COBRA (H1N1) hemagglutinin bound to CR6261 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-11-09
公開日2023-12-13
最終更新日2024-08-28
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6.
Structure, 32, 2024
8TP5
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H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1E04
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1E04, ...
著者Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B.
登録日2023-08-04
公開日2023-10-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Immune memory shapes human polyclonal antibody responses to H2N2 vaccination.
Biorxiv, 2023
8TPA
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BU of 8tpa by Molmil
H1 hemagglutinin (NC99) in complex with medial-junction-targeting Fab 2-2-1G06
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 2-2-1G06, ...
著者Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B.
登録日2023-08-04
公開日2023-10-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Immune memory shapes human polyclonal antibody responses to H2N2 vaccination.
Biorxiv, 2023
7SCN
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BU of 7scn by Molmil
Structure of H1 NC99 influenza hemagglutinin bound to Fab 310-63E6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-63E6 Fab, Heavy Chain, ...
著者Ward, A, Torrents de la Pena, A.
登録日2021-09-28
公開日2022-08-24
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus.
Immunity, 55, 2022
5C0R
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BU of 5c0r by Molmil
Crystal Structure of a Generation 3 Influenza Hemagglutinin Stabilized Stem Complexed with the Broadly Neutralizing Antibody C179
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C179 Fab heavy chain, ...
著者Boyington, J.C, kwong, P.D, Nabel, G.J, Mascola, J.R.
登録日2015-06-12
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.188 Å)
主引用文献Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection.
Nat. Med., 21, 2015
7SCO
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BU of 7sco by Molmil
Structure of H1 influenza hemagglutinin bound to Fab 310-39G10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 310-39G10 Fab, ...
著者Torrents de la Pena, A, Ward, A.B.
登録日2021-09-28
公開日2022-08-24
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus.
Immunity, 55, 2022
8TP3
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BU of 8tp3 by Molmil
H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1F05
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1F05, ...
著者Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B.
登録日2023-08-04
公開日2023-10-11
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Immune memory shapes human polyclonal antibody responses to H2N2 vaccination.
Biorxiv, 2023
8UR5
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BU of 8ur5 by Molmil
I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-1heptad-I53_dn5 (local refinement of TH-1heptad)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-10-25
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Cell Rep, 42, 2023
7MFG
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BU of 7mfg by Molmil
Cryo-EM structure of the VRC310 clinical trial, vaccine-elicited, human antibody 310-030-1D06 Fab in complex with an H1 NC99 HA trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-030-1D06 Heavy, 310-030-1D06 Light, ...
著者Gorman, J, Kwong, P.D.
登録日2021-04-09
公開日2021-11-03
最終更新日2022-03-09
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination.
Nat Med, 28, 2022
8UR7
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BU of 8ur7 by Molmil
I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-6heptad-I53_dn5 (local refinement of TH-6heptad)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-10-25
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Cell Rep, 42, 2023
8D21
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BU of 8d21 by Molmil
Cryo-EM structure of the VRC321 clinical trial, vaccine-elicited, human antibody 1B06 in complex with a stabilized NC99 HA trimer
分子名称: 1B06 Heavy Chain, 1B06 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorman, J, Kwong, P.D.
登録日2022-05-27
公開日2023-04-12
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans.
Sci Transl Med, 15, 2023
5C0S
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BU of 5c0s by Molmil
Crystal structure of a generation 4 influenza hemagglutinin stabilized stem in complex with the broadly neutralizing antibody CR6261
分子名称: CR6261 antibody heavy chain, CR6261 antibody light chain, Hemagglutinin, ...
著者Boyington, J.C, Kwong, P.D, Nabel, G.J, Mascola, J.R.
登録日2015-06-12
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection.
Nat. Med., 21, 2015

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件を2024-09-11に公開中

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