8TPA

H1 hemagglutinin (NC99) in complex with medial-junction-targeting Fab 2-2-1G06

Summary for 8TPA

• Entry DOI: 10.2210/pdb8tpa/pdb
• EMDB information: 41471
• Descriptor: Hemagglutinin HA1 chain, Heavy chain of Fab 2-2-1G06, Light chain of Fab 2-2-1G06, ... (6 entities in total)
• Functional Keywords: influenza, hemagglutinin, monoclonal antibody, immune complex, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus (A/New Caledonia/20/1999(H1N1)); More
• Total number of polymer chains: 12
• Total formula weight: 271396.50

Authors

Yang, Y.R.,Han, J.,Perrett, H.R.,Ward, A.B. (deposition date: 2023-08-04, release date: 2023-10-11)

• Primary citation: Yang, Y.R.,Han, J.,Perrett, H.R.,Richey, S.T.,Jackson, A.M.,Rodriguez, A.J.,Gillespie, R.A.,O'Connell, S.,Raab, J.E.,Cominsky, L.Y.,Chopde, A.,Kanekiyo, M.,Houser, K.V.,Chen, G.L.,McDermott, A.B.,Andrews, S.F.,Ward, A.B.; Immune memory shapes human polyclonal antibody responses to H2N2 vaccination.; Biorxiv, 2023; PubMed: 37781590; DOI: 10.1101/2023.08.23.554525

Experimental method

ELECTRON MICROSCOPY (3 Å)