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PDB: 7 件

5IDK
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BU of 5idk by Molmil
Crystal structure of West Nile Virus NS2B-NS3 protease in complex with a capped dipeptide boronate inhibitor
分子名称: ((R)-1-((S)-3-(4-(aminomethyl)phenyl)-2-benzamidopropaneamido)-4-guanidinobutyl)boronic acid, cyclic double ester with glycerol, DIMETHYL SULFOXIDE, ...
著者Hilgenfeld, R, Zhang, L.
登録日2016-02-24
公開日2016-12-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Peptide-Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology.
J. Med. Chem., 60, 2017
2FP7
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BU of 2fp7 by Molmil
West Nile Virus NS2B/NS3protease in complex with Bz-Nle-Lys-Arg-Arg-H
分子名称: Genome polyprotein, N-benzoyl-L-norleucyl-L-lysyl-N-[(2S)-5-carbamimidamido-1-hydroxypentan-2-yl]-L-argininamide
著者Schiering, N, D'Arcy, A, Erbel, P.
登録日2006-01-16
公開日2006-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus.
Nat.Struct.Mol.Biol., 13, 2006
2GGV
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BU of 2ggv by Molmil
Crystal structure of the West Nile virus NS2B-NS3 protease, His51Ala mutant
分子名称: non-structural protein 2B, non-structural protein 3
著者Aleshin, A.E, Shiryaev, S.A, Strongin, A.Y, Liddington, R.C.
登録日2006-03-24
公開日2007-03-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold.
Protein Sci., 16, 2007
2IJO
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BU of 2ijo by Molmil
Crystal Structure of the West Nile virus NS2B-NS3 protease complexed with bovine pancreatic trypsin inhibitor
分子名称: Pancreatic trypsin inhibitor, Polyprotein
著者Aleshin, A.E, Shiryaev, S.A, Strongin, A.Y, Liddington, R.C.
登録日2006-09-29
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold.
Protein Sci., 16, 2007
3E90
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BU of 3e90 by Molmil
West Nile vi rus NS2B-NS3protease in complexed with inhibitor Naph-KKR-H
分子名称: NS2B cofactor, NS3 protease, N~2~-(naphthalen-2-ylcarbonyl)-L-lysyl-N-[(1S)-4-carbamimidamido-1-formylbutyl]-L-lysinamide
著者Martin, J.L, Robin, G.
登録日2008-08-21
公開日2009-01-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation
J.Mol.Biol., 385, 2009
2P5P
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BU of 2p5p by Molmil
Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III
分子名称: Genome polyprotein
著者Gao, F, Yuan, F, Gao, G.F.
登録日2007-03-16
公開日2008-03-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III
To be Published
2YOL
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BU of 2yol by Molmil
West Nile Virus NS2B-NS3 protease in complex with 3,4- dichlorophenylacetyl-Lys-Lys-GCMA
分子名称: (S)-6-amino-N-((S)-6-amino-1-(((1r,4S)-4-guanidinocyclohexyl)methylamino)-1-oxohexan-2-yl)-2-(2-(3,4-dichlorophenyl)acetamido)hexanamide, CHLORIDE ION, NICKEL (II) ION, ...
著者Hammamy, M.Z, Haase, C, Hammami, M, Hilgenfeld, R, Steinmetzer, T.
登録日2012-10-25
公開日2013-03-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus Ns2B-Ns3 Protease.
Chemmedchem, 8, 2013

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件を2024-07-10に公開中

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