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PDB: 9 件
1YOV
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BU of 1yov by Molmil
Insights into the Ubiquitin Transfer Cascade from the refined structure of the activating enzyme for NEDD8
分子名称: Amyloid protein-binding protein 1, Ubiquitin-activating enzyme E1C, ZINC ION
著者Walden, H, Podgorski, M.S, Schulman, B.A.
登録日2005-01-28
公開日2005-03-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights into the Ubiquitin Transfer Cascade from the refined structure of the activating enzyme for NEDD8
Nature, 422, 2003
1TT5
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BU of 1tt5 by Molmil
Structure of APPBP1-UBA3-Ubc12N26: a unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8
分子名称: Ubiquitin-conjugating enzyme E2 M, ZINC ION, amyloid protein-binding protein 1, ...
著者Huang, D.T, Miller, D.W, Mathew, R, Cassell, R, Holton, J.M, Roussel, M.F, Schulman, B.A.
登録日2004-06-21
公開日2004-09-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.
Nat.Struct.Mol.Biol., 11, 2004
2NVU
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BU of 2nvu by Molmil
Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltose binding protein/NEDD8-activating enzyme E1 catalytic subunit chimera, ...
著者Huang, D.T, Hunt, H.W, Zhuang, M, Ohi, M.D, Holton, J.M, Schulman, B.A.
登録日2006-11-13
公開日2007-01-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
Nature, 445, 2007
3DBH
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BU of 3dbh by Molmil
Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8's E1 (APPBP1-UBA3Arg190Ala-NEDD8Ala72Arg)
分子名称: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ...
著者Souphron, J, Schulman, B.A.
登録日2008-05-31
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.
Biochemistry, 47, 2008
3DBL
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BU of 3dbl by Molmil
Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8's E1 (APPBP1-UBA3Arg190wt-NEDD8Ala72Gln)
分子名称: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ...
著者Souphron, J, Schulman, B.A.
登録日2008-06-01
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.
Biochemistry, 47, 2008
3GZN
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BU of 3gzn by Molmil
Structure of NEDD8-activating enzyme in complex with NEDD8 and MLN4924
分子名称: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ...
著者Sintchak, M.D.
登録日2009-04-07
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ.
Mol.Cell, 37, 2010
1R4M
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BU of 1r4m by Molmil
APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex
分子名称: Ubiquitin-like protein NEDD8, ZINC ION, amyloid beta precursor protein-binding protein 1, ...
著者Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A.
登録日2003-10-07
公開日2003-12-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12, 2003
3DBR
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BU of 3dbr by Molmil
Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8's E1 (APPBP1-UBA3Arg190Gln-NEDD8Ala72Arg)
分子名称: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ...
著者Souphron, J, Schulman, B.A.
登録日2008-06-02
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.
Biochemistry, 47, 2008
1R4N
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BU of 1r4n by Molmil
APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Ubiquitin-like protein NEDD8, ZINC ION, ...
著者Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A.
登録日2003-10-07
公開日2003-12-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12, 2003

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件を2024-09-04に公開中

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