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PDB: 19 件
7TYS
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BU of 7tys by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the up conformation
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-02-14
公開日2022-08-31
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7U24
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BU of 7u24 by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and glibenclamide with Kir6.2-CTD in the up conformation
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ...
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-02-23
公開日2022-08-31
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7TYT
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BU of 7tyt by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the down conformation
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-02-14
公開日2022-08-31
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
6BAA
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BU of 6baa by Molmil
Cryo-EM structure of the pancreatic beta-cell KATP channel bound to ATP and glibenclamide
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Martin, G.M, Yoshioka, C, Shyng, S.L.
登録日2017-10-12
公開日2017-11-01
最終更新日2019-12-25
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Anti-diabetic drug binding site in a mammalian KATPchannel revealed by Cryo-EM.
Elife, 6, 2017
6PZ9
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BU of 6pz9 by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, ...
著者Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日2019-07-31
公開日2019-08-14
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6PZA
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BU of 6pza by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and glibenclamide
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日2019-07-31
公開日2019-08-14
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
7U1S
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BU of 7u1s by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-out conformation
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-02-22
公開日2022-08-31
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7U1Q
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BU of 7u1q by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-in conformation
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-02-21
公開日2022-08-31
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7U2X
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BU of 7u2x by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the down conformation
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-02-25
公開日2022-08-31
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
6PZC
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BU of 6pzc by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to carbamazepine
分子名称: ATP-binding cassette sub-family C member 8
著者Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日2019-07-31
公開日2019-08-14
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.34 Å)
主引用文献Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6PZI
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BU of 6pzi by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8
著者Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日2019-07-31
公開日2019-08-14
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
7U1E
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BU of 7u1e by Molmil
CryoEM structure of the pancreatic ATP-sensitive potassium channel bound to ATP with Kir6.2-CTD in the down conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-02-21
公開日2022-08-31
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (4.52 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7UQR
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BU of 7uqr by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the apo form with Kir6.2-CTD in the down conformation
分子名称: ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-04-20
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
6PZB
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BU of 6pzb by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 Apo state
分子名称: ATP-binding cassette sub-family C member 8
著者Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日2019-07-31
公開日2019-08-14
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
5YWB
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BU of 5ywb by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class2 at 5.2A)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-30
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
7U7M
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BU of 7u7m by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the up conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-03-07
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7UAA
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BU of 7uaa by Molmil
CryoEM structure of the pancreatic ATP-sensitive potassium channel in the ATP-bound state with Kir6.2-CTD in the up conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-03-11
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
5TWV
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BU of 5twv by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive K+ channel SUR1/Kir6.2 in the presence of ATP and glibenclamide
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
著者Martin, G.M, Yoshioka, C, Chen, J.Z, Shyng, S.L.
登録日2016-11-14
公開日2017-01-25
最終更新日2019-12-25
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating.
Elife, 6, 2017
7U6Y
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BU of 7u6y by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of glibenclamide and ATP with Kir6.2-CTD in the down conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-03-06
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022

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