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PDB: 94 件
1IUY
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BU of 1iuy by Molmil
Solution structure of the cullin-3 homologue
分子名称: cullin-3 homologue
著者Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-03-08
公開日2003-10-07
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the cullin-3 homologue
To be published
2DO7
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BU of 2do7 by Molmil
Solution structure of the winged helix-turn-helix motif of human CUL-4B
分子名称: Cullin-4B
著者Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-27
公開日2007-04-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the winged helix-turn-helix motif of human CUL-4B
To be Published
6TTU
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BU of 6ttu by Molmil
Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2
分子名称: CYS-LYS-LYS-ALA-ARG-HIS-ASP-SEP-GLY, Cullin-1, E3 ubiquitin-protein ligase RBX1, ...
著者Baek, K, Prabu, J.R, Schulman, B.A.
登録日2019-12-30
公開日2020-02-12
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly.
Nature, 578, 2020
7PLO
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BU of 7plo by Molmil
H. sapiens replisome-CUL2/LRR1 complex
分子名称: Cell division control protein 45 homolog, Claspin, Cullin-2, ...
著者Jones, M.J, Yeeles, J.T.P, Deegan, T.D, Jenkyn-Bedford, M.
登録日2021-09-01
公開日2021-11-10
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
9KBD
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BU of 9kbd by Molmil
Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO3 SCF ubiquition ligase complex
分子名称: Cullin-1, E3 ubiquitin-protein ligase RBX1, F-box only protein 3, ...
著者Wei, J, Xu, C.
登録日2024-10-30
公開日2025-02-19
最終更新日2025-02-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural Insight Into the SKP1-CUL1-FBXO3-RBX1 Complex.
Proteins, 2025
6V9I
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BU of 6v9i by Molmil
cryo-EM structure of Cullin5 bound to RING-box protein 2 (Cul5-Rbx2)
分子名称: Immunoglobulin G-binding protein G,Cullin-5, RING-box protein 2, ZINC ION
著者Komives, E.A, Lumpkin, R.J, Baker, R.W, Leschziner, A.E.
登録日2019-12-13
公開日2020-04-29
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Structure and dynamics of the ASB9 CUL-RING E3 Ligase.
Nat Commun, 11, 2020
5N4W
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BU of 5n4w by Molmil
Crystal structure of the Cul2-Rbx1-EloBC-VHL ubiquitin ligase complex
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ...
著者Cardote, T.A.F, Gadd, M.S, Ciulli, A.
登録日2017-02-11
公開日2017-06-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex.
Structure, 25, 2017
9JKB
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BU of 9jkb by Molmil
Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO4 SCF ubiquition ligase complex
分子名称: Cullin-1, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Zhu, W, Xu, C.
登録日2024-09-15
公開日2024-10-23
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Structure of the CUL1-RBX1-SKP1-FBXO4 SCF ubiquitin ligase complex.
Biochem.Biophys.Res.Commun., 735, 2024
5V89
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Structure of DCN4 PONY domain bound to CUL1 WHB
分子名称: Cullin-1, DCN1-like protein 4
著者Guy, R.K, Schulman, B.A, Scott, D.C, Hammill, J.T.
登録日2017-03-21
公開日2017-05-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.
Nat. Chem. Biol., 13, 2017
4P5O
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BU of 4p5o by Molmil
Structure of an RBX1-UBC12~NEDD8-CUL1-DCN1 complex: a RING-E3-E2~ubiquitin-like protein-substrate intermediate trapped in action
分子名称: Cullin-1, DCN1-like protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Scott, D.C, Schulman, B.A.
登録日2014-03-18
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.1071 Å)
主引用文献Structure of a RING E3 Trapped in Action Reveals Ligation Mechanism for the Ubiquitin-like Protein NEDD8.
Cell, 157, 2014
2HYE
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BU of 2hye by Molmil
Crystal Structure of the DDB1-Cul4A-Rbx1-SV5V Complex
分子名称: Cullin-4A, DNA damage-binding protein 1, Nonstructural protein V, ...
著者Angers, S, Li, T, Yi, X, MacCoss, M.J, Moon, R.T, Zheng, N.
登録日2006-08-05
公開日2006-10-03
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.
Nature, 443, 2006
1U6G
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BU of 1u6g by Molmil
Crystal Structure of The Cand1-Cul1-Roc1 Complex
分子名称: Cullin homolog 1, RING-box protein 1, TIP120 protein, ...
著者Goldenberg, S.J, Shumway, S.D, Cascio, T.C, Garbutt, K.C, Liu, J, Xiong, Y, Zheng, N.
登録日2004-07-29
公開日2004-12-14
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases
Cell(Cambridge,Mass.), 119, 2004
3RTR
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BU of 3rtr by Molmil
A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases
分子名称: Cullin-1, E3 ubiquitin-protein ligase RBX1, ZINC ION
著者Calabrese, M.F, Scott, D.C, Duda, D.M, Grace, C.R, Kurinov, I, Kriwacki, R.W, Schulman, B.A.
登録日2011-05-03
公開日2011-07-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases.
Nat.Struct.Mol.Biol., 18, 2011
1LDK
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BU of 1ldk by Molmil
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex
分子名称: CULLIN HOMOLOG, CYCLIN A/CDK2-ASSOCIATED PROTEIN P19, SKP2-like protein type gamma, ...
著者Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P.
登録日2002-04-08
公開日2002-05-08
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416, 2002
1LDJ
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BU of 1ldj by Molmil
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex
分子名称: Cullin homolog 1, ZINC ION, ring-box protein 1
著者Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P.
登録日2002-04-08
公開日2002-05-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416, 2002
3TDZ
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BU of 3tdz by Molmil
N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex: Structure of a human Cul1WHB-Dcn1P-stapled acetylated Ubc12N complex
分子名称: Cullin-1, DCN1-like protein 1, STAPLED PEPTIDE
著者Scott, D.C, Monda, J.K, Bennett, E.J, Harper, J.W, Schulman, B.A.
登録日2011-08-11
公開日2011-10-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.
Science, 334, 2011
3TDU
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BU of 3tdu by Molmil
N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex: Structure of a human Cul1WHB-Dcn1P-acetylated Ubc12N complex
分子名称: Cullin-1, DCN1-like protein 1, NEDD8-conjugating enzyme Ubc12
著者Scott, D.C, Monda, J.K, Bennett, E.J, Harper, J.W, Schulman, B.A.
登録日2011-08-11
公開日2011-10-12
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.
Science, 334, 2011
7SHK
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BU of 7shk by Molmil
Structure of Xenopus laevis CRL2Lrr1 (State 1)
分子名称: CULLIN_2 domain-containing protein, Elongin-C, Lrr1, ...
著者Zhou, H, Brown, A.
登録日2021-10-09
公開日2021-12-08
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of CRL2Lrr1, the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates.
Nucleic Acids Res., 49, 2021
7SHL
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BU of 7shl by Molmil
Structure of Xenopus laevis CRL2Lrr1 (State 2)
分子名称: CULLIN_2 domain-containing protein, Elongin-C, Lrr1, ...
著者Zhou, H, Brown, A.
登録日2021-10-09
公開日2021-12-08
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of CRL2Lrr1, the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates.
Nucleic Acids Res., 49, 2021
3DQV
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BU of 3dqv by Molmil
Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation
分子名称: Cullin-5, NEDD8, Rbx1, ...
著者Duda, D.M, Borg, L.A, Scott, D.C, Hunt, H.W, Hammel, M, Schulman, B.A.
登録日2008-07-09
公開日2008-09-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
Cell(Cambridge,Mass.), 134, 2008
3DPL
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BU of 3dpl by Molmil
Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation.
分子名称: Cullin-5, RING-box protein 1, ZINC ION
著者Duda, D.M, Schulman, B.A.
登録日2008-07-08
公開日2008-09-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
Cell(Cambridge,Mass.), 134, 2008
3O6B
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BU of 3o6b by Molmil
A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB) low resolution
分子名称: Cell division control protein 53, Defective in cullin neddylation protein 1
著者Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A.
登録日2010-07-28
公開日2010-09-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
3O2P
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A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB)
分子名称: Cell division control protein 53, Defective in cullin neddylation protein 1, GLYCEROL
著者Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A.
登録日2010-07-22
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.233 Å)
主引用文献A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
4A0K
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STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX
分子名称: 12 BP DNA, 12 BP THF CONTAINING DNA, CULLIN-4A, ...
著者Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H.
登録日2011-09-09
公開日2011-12-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (5.93 Å)
主引用文献The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
4A0C
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Structure of the CAND1-CUL4B-RBX1 complex
分子名称: CULLIN-4B, CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1, E3 UBIQUITIN-PROTEIN LIGASE RBX1, ...
著者Scrima, A, Fischer, E.S, Faty, M, Gut, H, Thoma, N.H.
登録日2011-09-08
公開日2011-11-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
Cell(Cambridge,Mass.), 147, 2011

 

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