1IWC
| TFE-induded structure of the N-terminal domain of pig gastric H/K-ATPase | 分子名称: | gastric H/K-ATPase | 著者 | Fujitani, N, Kanagawa, M, Aizawa, T, Ohkubo, T, Kaya, S, Demura, M, Kawano, K, Taniguchi, K, Nitta, K. | 登録日 | 2002-05-02 | 公開日 | 2002-11-27 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure determination and conformational change induced by tyrosine phosphorylation of the N-terminal domain of the alpha-chain of pig gastric H+/K+-ATPase Biochem.Biophys.Res.Commun., 300, 2003
|
|
1IWF
| Solution structure of the N-terminal domain of pig gastric H/K-ATPase | 分子名称: | gastric H/K-ATPase | 著者 | Fujitani, N, Kanagawa, M, Aizawa, T, Ohkubo, T, Kaya, S, Demura, M, Kawano, K, Taniguchi, K, Nitta, K. | 登録日 | 2002-05-06 | 公開日 | 2002-11-27 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure determination and conformational change induced by tyrosine phosphorylation of the N-terminal domain of the alpha-chain of pig gastric H+/K+-ATPase Biochem.Biophys.Res.Commun., 300, 2003
|
|
8WA5
| |
8JMN
| Cryo-EM structure of the gastric proton pump with bound DQ-21 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[4-[[2-[(4-chlorophenyl)methoxy]phenyl]methoxy]phenyl]-N-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-06-05 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
|
|
3IXZ
| Pig gastric H+/K+-ATPase complexed with aluminium fluoride | 分子名称: | Potassium-transporting ATPase alpha, Potassium-transporting ATPase subunit beta | 著者 | Abe, K, Tani, K, Nishizawa, T, Fujiyoshi, Y. | 登録日 | 2009-03-09 | 公開日 | 2009-06-23 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6.5 Å) | 主引用文献 | Inter-subunit interaction of gastric H+,K+-ATPase prevents reverse reaction of the transport cycle Embo J., 28, 2009
|
|
4UX2
| Cryo-EM structure of antagonist-bound E2P gastric H,K-ATPase (SCH.E2. MgF) | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | 著者 | Abe, K, Tani, K, Fujiyoshi, Y. | 登録日 | 2014-08-18 | 公開日 | 2014-09-17 | 最終更新日 | 2014-11-12 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (7 Å) | 主引用文献 | Systematic Comparison of Molecular Conformations of H+,K+-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating. J.Biol.Chem., 289, 2014
|
|
4UX1
| Cryo-EM structure of antagonist-bound E2P gastric H,K-ATPase (SCH.E2. AlF) | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | 著者 | Abe, K, Tani, K, Fujiyoshi, Y. | 登録日 | 2014-08-18 | 公開日 | 2014-09-17 | 最終更新日 | 2014-11-12 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (8 Å) | 主引用文献 | Systematic Comparison of Molecular Conformations of H+,K+-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating. J.Biol.Chem., 289, 2014
|
|
2XZB
| Pig Gastric H,K-ATPase with bound BeF and SCH28080 | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | 著者 | Abe, K, Tani, K, Fujiyoshi, Y. | 登録日 | 2010-11-24 | 公開日 | 2011-01-26 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (7 Å) | 主引用文献 | Conformational Rearrangement of Gastric H(+),K(+)- ATPase Induced by an Acid Suppressant. Nat.Commun., 2, 2011
|
|
2YN9
| Cryo-EM structure of gastric H+,K+-ATPase with bound rubidium | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | 著者 | Abe, K, Tani, K, Friedrich, T, Fujiyoshi, Y. | 登録日 | 2012-10-13 | 公開日 | 2012-11-07 | 最終更新日 | 2014-07-16 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (8 Å) | 主引用文献 | Cryo-Em Structure of Gastric H+,K+-ATPase with a Single Occupied Cation-Binding Site. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
8IJW
| Cryo-EM structure of the gastric proton pump with bound DQ-06 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-02-28 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.19 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
|
|
8IJX
| Cryo-EM structure of the gastric proton pump with bound DQ-18 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[4-[(5-chloranyl-2-phenylmethoxy-phenyl)methoxy]phenyl]-N-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-02-28 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.08 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
|
|
8IJV
| Cryo-EM structure of the gastric proton pump with bound DQ-02 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[[5-chloranyl-2-(4-chlorophenyl)phenyl]methoxy]-N-methyl-but-2-yn-1-amine, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-02-28 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
|
|
5YLV
| Crystal structure of the gastric proton pump complexed with SCH28080 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(2-methyl-8-phenylmethoxy-imidazo[1,2-a]pyridin-3-yl)ethanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | 登録日 | 2017-10-19 | 公開日 | 2018-04-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.79977775 Å) | 主引用文献 | Crystal structures of the gastric proton pump Nature, 556, 2018
|
|
5Y0B
| PIG GASTRIC H+,K+ - ATPASE IN COMPLEX with BYK99 | 分子名称: | Potassium-transporting ATPase alpha chain 1, Potassium-transporting ATPase subunit beta | 著者 | Abe, K, Shimokawa, J, Natio, M, Munson, K, Vagin, O, Sachs, G, Suzuki, H, Tani, K, Fujiyoshi, Y. | 登録日 | 2017-07-16 | 公開日 | 2017-08-09 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6.7 Å) | 主引用文献 | The cryo-EM structure of gastric H(+),K(+)-ATPase with bound BYK99, a high-affinity member of K(+)-competitive, imidazo[1,2-a]pyridine inhibitors Sci Rep, 7, 2017
|
|
5YLU
| Crystal structure of the gastric proton pump complexed with vonoprazan | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonyl-pyrrol-3-yl]-~{N}-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | 登録日 | 2017-10-19 | 公開日 | 2018-04-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.79988956 Å) | 主引用文献 | Crystal structures of the gastric proton pump Nature, 556, 2018
|
|
7W47
| Crystal structure of the gastric proton pump complexed with tegoprazan | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Potassium-transporting ATPase alpha chain 1, ... | 著者 | Abe, K, Tanaka, S, Morita, M, Yamagishi, T. | 登録日 | 2021-11-26 | 公開日 | 2022-01-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump. J.Med.Chem., 65, 2022
|
|
7W48
| |
7W49
| |
7W4A
| Cryo-EM structure of the gastric proton pump complexed with revaprazan | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... | 著者 | Abe, K, Tanaka, S, Morita, M, Yamagishi, T. | 登録日 | 2021-11-26 | 公開日 | 2022-03-02 | 最終更新日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump. J.Med.Chem., 65, 2022
|
|