8IJV
Cryo-EM structure of the gastric proton pump with bound DQ-02
Summary for 8IJV
Entry DOI | 10.2210/pdb8ijv/pdb |
EMDB information | 35500 |
Descriptor | Sodium/potassium-transporting ATPase subunit alpha, Potassium-transporting ATPase subunit beta, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (8 entities in total) |
Functional Keywords | p-type atpase, p2-type atpase, membrane protein |
Biological source | Sus scrofa (pig) More |
Total number of polymer chains | 2 |
Total formula weight | 153170.47 |
Authors | Abe, K.,Yokoshima, S.,Yoshimori, A. (deposition date: 2023-02-28, release date: 2023-08-30, Last modification date: 2023-10-04) |
Primary citation | Abe, K.,Ozako, M.,Inukai, M.,Matsuyuki, Y.,Kitayama, S.,Kanai, C.,Nagai, C.,Gopalasingam, C.C.,Gerle, C.,Shigematsu, H.,Umekubo, N.,Yokoshima, S.,Yoshimori, A. Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6:956-956, 2023 Cited by PubMed: 37726448DOI: 10.1038/s42003-023-05334-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.1 Å) |
Structure validation
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