6BTX
 
 | | Structure of a bacterial metal transporter | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, NICKEL (II) ION, ... | | 著者 | Jormakka, M, Deshpande, C.N. | | 登録日 | 2017-12-08 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Calcium is an essential cofactor for metal efflux by the ferroportin transporter family.
Nat Commun, 9, 2018
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6WIK
 | | Cryo-EM structure of SLC40/ferroportin with Fab in the presence of hepcidin | | 分子名称: | 11F9 Fab heavy-chain, 11F9 Fab light-chain, Solute carrier family 40 protein | | 著者 | Shen, J, Ren, Z, Pan, Y, Gao, S, Yan, N, Zhou, M. | | 登録日 | 2020-04-10 | | 公開日 | 2020-11-11 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of ion transport and inhibition in ferroportin.
Nat Commun, 11, 2020
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8C03
 | | Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy12 in outward-facing conformation | | 分子名称: | 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, Solute carrier family 40 member 1 | | 著者 | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | 登録日 | 2022-12-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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8C02
 | | Structure of SLC40/ferroportin in complex with synthetic nanobody Sy3 in occluded conformation | | 分子名称: | Solute carrier family 40 member 1, Sybody3 | | 著者 | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | 登録日 | 2022-12-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | | 主引用文献 | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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8DL8
 | | Cryo-EM structure of human ferroportin/slc40 bound to Co2+ in nanodisc | | 分子名称: | 11F9 heavy-chain, 11F9 light-chain, COBALT (II) ION, ... | | 著者 | Shen, J, Wilbon, A.S, Pan, Y, Zhou, M. | | 登録日 | 2022-07-07 | | 公開日 | 2022-12-07 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of ferroportin inhibition by minihepcidin PR73.
Plos Biol., 21, 2023
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8DL7
 | | Cryo-EM structure of human ferroportin/slc40 bound to minihepcidin PR73 in nanodisc | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 11F9 heavy-chain, 11F9 light-chain, ... | | 著者 | Shen, J, Wilbon, A.S, Pan, Y, Zhou, M. | | 登録日 | 2022-07-07 | | 公開日 | 2022-12-07 | | 最終更新日 | 2025-05-21 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis of ferroportin inhibition by minihepcidin PR73.
Plos Biol., 21, 2023
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8DL6
 | | Cryo-EM structure of human ferroportin/slc40 bound to Ca2+ in nanodisc | | 分子名称: | 11F9 heavy-chain, 11F9 light-chain, CALCIUM ION, ... | | 著者 | Shen, J, Wilbon, A.S, Pan, Y, Zhou, M. | | 登録日 | 2022-07-07 | | 公開日 | 2023-01-25 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism of Ca 2+ transport by ferroportin.
Elife, 12, 2023
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5AYN
 | | Crystal structure of a bacterial homologue of iron transporter ferroportin in outward-facing state | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, POTASSIUM ION, Solute carrier family 39 (Iron-regulated transporter) | | 著者 | Taniguchi, R, Kato, H.E, Font, J, Deshpande, C.N, Ishitani, R, Jormakka, M, Nureki, O. | | 登録日 | 2015-08-25 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin
Nat Commun, 6, 2015
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6VYH
 | | Cryo-EM structure of SLC40/ferroportin in complex with Fab | | 分子名称: | 11F9 heavy-chain, 11F9 light-chain, COBALT (II) ION, ... | | 著者 | Shen, J, Ren, Z, Pan, Y, Gao, S, Yan, N, Zhou, M. | | 登録日 | 2020-02-26 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of ion transport and inhibition in ferroportin.
Nat Commun, 11, 2020
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5AYO
 | | Crystal structure of a bacterial homologue of iron transporter ferroportin in inward-facing state | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, POTASSIUM ION, Solute carrier family 39 (Iron-regulated transporter), ... | | 著者 | Taniguchi, R, Kato, H.E, Font, J, Deshpande, C.N, Ishitani, R, Jormakka, M, Nureki, O. | | 登録日 | 2015-08-25 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin
Nat Commun, 6, 2015
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6W4S
 | | Structure of apo human ferroportin in lipid nanodisc | | 分子名称: | Fab45D8 Heavy Chain, Fab45D8 Light Chain, Solute carrier family 40 member 1 | | 著者 | Billesboelle, C.B, Azumaya, C.M, Gonen, S, Powers, A, Kretsch, R.C, Schneider, S, Arvedson, T, Dror, R.O, Cheng, Y, Manglik, A. | | 登録日 | 2020-03-11 | | 公開日 | 2020-09-09 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms.
Nature, 586, 2020
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5AYM
 | | Crystal structure of a bacterial homologue of iron transporter ferroportin in outward-facing state with soaked iron | | 分子名称: | FE (II) ION, Solute carrier family 39 (Iron-regulated transporter) | | 著者 | Taniguchi, R, Kato, H.E, Font, J, Deshpande, C.N, Ishitani, R, Jormakka, M, Nureki, O. | | 登録日 | 2015-08-25 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin
Nat Commun, 6, 2015
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6WBV
 | | Structure of human ferroportin bound to hepcidin and cobalt in lipid nanodisc | | 分子名称: | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, COBALT (II) ION, Fab45D8 Heavy Chain, ... | | 著者 | Billesboelle, C.B, Azumaya, C.M, Gonen, S, Powers, A, Kretsch, R.C, Schneider, S, Arvedson, T, Dror, R.O, Cheng, Y, Manglik, A. | | 登録日 | 2020-03-27 | | 公開日 | 2020-09-09 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms.
Nature, 586, 2020
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